TERF1 antibody

Principal name

TERF1 antibody

Alternative names for TERF1 antibody

PIN2, TRBF1, TRF, TRF1, Telomeric repeat-binding factor 1, TTAGGG repeat-binding factor 1, NIMA-interacting protein 2, Telomeric protein Pin2/TRF1

SwissProt ID

P54274 (Human), P70371 (Mouse)

Gene ID

7013 (TERF1)

Available reactivities

Hu (Human), Hst (Hamster), Mky (Monkey), Ms (Mouse), Rt (Rat), Bov (Bovine), Por (Porcine), Prim (Primate)

Available hosts

Mouse, Rabbit, Goat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Frozen Sections (C)

Background of TERF1 antibody

Along with tankyrase-1, TIN2, and PINX1, TRF1 binds the double-stranded TTAGGG repeat of telomeres and regulates telomere length. Protection of telomeres-1 (POT1) is a single-stranded telomeric DNA-binding protein which controls the elongation of telomeres by telomerase. TRF1 mediates the loading of POT1 onto single stranded DNA, conveying information about telomere length to the telomere terminus, where telomerase is regulated. If the telomere is long enough, telomerase is inhibited. Additionally in conjunction with POT1 and TTAGGG repeat binding factor 1 (TRF2), TRF1 recruits factors to the telomere, inducing the formation of the protective t-loop. TRF1 along with TRF2, POT1, TIN2, TPP1, and Rap1 form the shelterin complex which distinguishes telomeres from sites of DNA damage.
TRF1 is thought to play a role in leukaemia being expressed at significantly higher levels in patients with acute lymphoblastic leukaemia than those with myeloid leukaemia.

General readings

Chong L, van Steensel B, Broccoli D, Erdjument-Bromage H, Hanish J, Tempst P, de Lange T.
A human telomeric protein.
Science. 1995 Dec 8;270(5242):1663-7.
PMID: 7502076

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TERF1 (C-term) antibody

TA302766 staining (2µg/ml) of HeLa lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 12 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TERF1 antibody

Western Blot: TRF1 Antibody (57-6) - Western blot detection of TRF1. 50 ugs of total lysate each lane. Mouse IgG1 57-6 Purified Hu, Ms, Prim, Rt E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TERF1 antibody

Predicted band size: 50kDa. Positive control: Human fetal kidney tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 50 ug Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 5 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TERF1 antibody

Predicted band size: 50kDa. Positive control: 293T and Hela cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1:293T cell lysate Lane2: Hela cell lysate Lysates: 50 ug per lane Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 5 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TERF1 antibody

TA329083 (0.3µg/ml) staining of Human Testis lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TERF1 antibody

TERF1 Mouse IgG1 BED5 Purified Hu C, E, P, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

TERF1 (C-term) antibody

Western blot analysis of anti-TERF1(C-term) Pab (Cat.#AP12398PU-N) in Jurkat cell line lysates (35ug/lane). TERF1 (C-term)(arrow) was detected using the purified Pab (1:60 dilution). Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TERF1 antibody

Immunohistochemistry analyzes of TRF1 antibody (AP20371PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

TERF1 antibody

TERF1 Mouse Hu ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

TERF1 antibody

Western blot analysis of TRF1 using TERF1 monoclonal antibody, clone 57-6 ( Cat # MAB2400 ). 50 µg of total lysate were used each lane. Mouse IgG1 Jun-57 Hu, Ms, Rt E, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

TERF1 antibody

TERF1 Mouse IgG1 3H11 Hu E, ICC/IF, WB
50 µl / €470.00
  Abnova Taiwan Corp.

TERF1 antibody

Western blot analysis of TERF1 in 20 µgs of ( A ) Jurkat and ( B ) 293 cell lysate. Using TERF1 polyclonal antibody ( Cat # PAB012 ) at 7 µg/ml. Rabbit Hu WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

TERF1 antibody

Western blot analysis of TERF1 polyclonal antibody ( Cat # PAB2607 ) in Jurkat cell line lysates ( 35 µg/lane ) . TERF1 ( C-term ) ( arrow ) was detected using the purified polyclonal antibody ( 1 : 60 dilution ) . Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

TERF1 antibody

TERF1 polyclonal antibody ( Cat # PAB6118 ) staining ( 2 µg/ml ) of HeLa lysate ( RIPA buffer, 30 µg total protein per lane ) . Primary incubated for 12 hour. Detected by western blot using chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

TERF1 pSer219 antibody

Western blot analysis of extracts from 293 cells treated with paclitaxel 1uM 24h, using Telomeric Repeat Binding Factor 1 (Phospho-Ser219) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €205.00
  Assay Biotech

TERF1 pSer219 antibody

Western blot analysis of extracts from 293 cells treated with paclitaxel 1uM 24h, using Telomeric Repeat Binding Factor 1 (Phospho-Ser219) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €310.00
  Assay Biotech

TERF1 antibody

Western blot analysis of extracts from 293 cells, treated with Paclitaxel 1uM 24h, using Telomeric Repeat Binding Factor 1 (Ab-219) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €205.00
  Assay Biotech

TERF1 antibody

Western blot analysis of extracts from 293 cells, treated with Paclitaxel 1uM 24h, using Telomeric Repeat Binding Factor 1 (Ab-219) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €310.00
  Assay Biotech

TERF1 pSer219 antibody

Western blot analysis of TERF1 (pS219) expression in DLD UV-treated (A); Raw264.7 UV-treated (B); PC12 UV-treated (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €210.00
  Cohesion Biosciences Ltd.

TERF1 pSer219 antibody

Western blot analysis of TERF1 (pS219) expression in DLD UV-treated (A); Raw264.7 UV-treated (B); PC12 UV-treated (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €330.00
  Cohesion Biosciences Ltd.

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