TERT antibody

Principal name

TERT antibody

Alternative names for TERT antibody

Telomerase reverse transcriptase, HEST2, EST2, TCS1, TRT, Telomerase catalytic subunit, Telomerase-associated protein 2

SwissProt ID

O14746 (Human), O70372 (Mouse), Q27ID4 (Bovin), Q673L6 (Rat), Q6A548 (Canfa)

Gene ID

7015 (TERT), 7015249 (alr), 21752 (Tert)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Mouse, Rabbit, Goat, Chicken

Available applications

Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Frozen Sections (C), Enzyme Immunoassay (E), Dot blot (Dot)

Background of TERT antibody

Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Telomerase are large DNA-protein complexes with telomerase expression being the subject of recent research due to its link to cell immortalization. Recent evidence has shown that MYC upregulates the catalytic subunit of telomerase, TERT, and that Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. [provided by RefSeq, Jul 2008].

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TERT (627-656) antibody

Fluorescent confocal image of SY5Y cells stained with TERT antibody. SY5Y cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.2%, 30 min). Cells were then incubated TERT primary antibody (1:200, 2 h at room temperature). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:1000, 1h). Nuclei were counterstained with Hoechst 33342 (blue) (10 ug/ml, 5 min). TERT immunoreactivity is localized to the nucleus of SY5Y cells. Rabbit Purified Hu F, ICC/IF, P, WB
0.2 ml / €470.00
  Acris Antibodies GmbH

TERT (Super Novus Pack) antibody

Pancreatic carcinoma showing strong staining of tumor cells Mouse IgM var. Ascites Hu F, ICC/IF, P, WB
2 vials / €490.00
  Novus Biologicals Inc.

TERT (597-611) antibody

Staining of Skeletal Muscle lysate (35µg protein in RIPA buffer) using TERT Antibody Cat.-No AP31849PU-N at 0.5 µg/ml. Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

TERT antibody

Western Blot analysis of human TERT Mouse IgM 2D8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TERT antibody

Western Blot analysis of human TERT 1:500 dilution on MJ90 cells Mouse IgM 2C4 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TERT antibody

Immunofluorescence analysis of HUVEC cells, using Telomerase antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

TERT antibody

Predicted cell location: Cytoplasm. Positive control: Human gastric cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TERT antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TERT antibody

Predicted cell location: Cytoplasm . Positive control: Human tonsil and esophagus cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human tonsil tissue using TERT antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TERT antibody

Predicted cell location: Cytoplasm or Nucleus . Positive control: Human thyroid and ovarian cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using TERT antibody at dilution 1/50, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TERT (Center) antibody

Western blot analysis of anti-TERT Antibody (Center) (RB14069) in Jurkat cell line lysates (35ug/lane). TERT(arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

TERT antibody

Western Blot: Telomerase reverse transcriptase Antibody [TA336564] - Detection of Telomerase reverse transcriptase in HeLa nuclear extracts using TA336564. Rabbit Purified Hu, Ms ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TERT antibody

Western blot analysis of TERT expression in Jurkat cell extracts Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TERT pSer1125 antibody

Dot blot analysis of anti-Phospho-TERT pSer1125 Antibody (Cat.#AP12956PU-N) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. Rabbit Ig Aff - Purified Hu
0.4 ml / €370.00
  Acris Antibodies GmbH

TERT pTyr707 antibody

Dot blot analysis of anti-Phospho-TERT-pY707 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. Rabbit Ig Aff - Purified Hu
0.4 ml / €370.00
  Acris Antibodies GmbH

TERT antibody

Western blot analysis of human TERT using TERT monoclonal antibody, clone 2D8 ( Cat # MAB2379 ). Sample : MJ90 whole cell lysate. Mouse IgM 2D8 Hu ICC/IF, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

TERT antibody

Western blot analysis of TERT polyclonal antibody ( Cat # PAB2490 ) in Jurkat cell line lysates ( 35 µg/lane ) . TERT ( arrow ) was detected using the purified polyclonal antibody ( 1 : 60 dilution ) . Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

TERT pSer1125 antibody

Dot blot analysis of TERT (phospho S1125) polyclonal antibody ( Cat # PAB4934 ) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/ml. Rabbit Hu Dot, E
0.4 ml / €400.00
  Abnova Taiwan Corp.

TERT antibody

Western blot analysis of TERT in HeLa nuclear extracts with TERT polyclonal antibody ( Cat# PAB12002 ). Rabbit Hu WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

TERT pSer227 antibody

Immunofluorescence analysis of HuvEc cells, using Telomerase (Phospho-Ser227) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF
50 µg / €205.00
  Assay Biotech

TERT pSer227 antibody

Immunofluorescence analysis of HuvEc cells, using Telomerase (Phospho-Ser227) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF
0.1 mg / €310.00
  Assay Biotech

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