TFEC antibody

Principal name

TFEC antibody

Alternative names for TFEC antibody

Transcription factor EC, TFE-C, TCFEC, TFECL, TFEC-L, Transcription factor EC-like

SwissProt ID

A4IFU7 (Bovin), O14948 (Human), Q63302 (Rat), Q9WTW4 (Mouse)

Gene ID

22797 (TFEC), 21426 (Tfec)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP)

Background of TFEC antibody

The DNA-binding factor TFE3 contains adjacent helix-loop-helix (HLH) and leucine zipper (LZ) domains flanked by an upstream basic region. These protein motifs are frequently observed in other transcription factors and are particularly common to members of the Myc family. TFE3 is ubiquitously expressed and can directly associates with DNA as either homodimers or heterodimers formed with two related proteins, TFEB or TFEC. TFE3 binds to and activates the microE3 motif of the immunoglobulin heavy-chain enhancer to induce B-cell-specific gene transcription and DNA recombination. TFEB binds to the major late promoter of adenovirus and specifically associates with DNA as both a homodimer and a heterodimer with TFE3. TFEB is expressed at low levels in the embryo but at high levels in the trophoblast cells of the placenta, where it plays a critical role in regulating normal vascularization of the placenta.
TFEC shares a bHLH/LZ structure with TFE3 and a closely related protein microphthalmia-associated transcription factor (MITF), which is critically involved in melanocyte differentiation. Unlike TFE3, the expression of TFEC is largely restricted to fibroblasts, myoblasts, chondrosarcoma cells, and myeloma cells.

General readings

Yasumoto K, Shibahara S.
Molecular cloning of cDNA encoding a human TFEC isoform, a newly identified transcriptional regulator.
Biochim Biophys Acta. 1997 Jul 17;1353(1):23-31.
PMID: 9256061

14 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TFEC (N-term) antibody

TA302789 staining (1µg/ml) of Human Testis lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TFEC antibody

Sample (30 ug of whole cell lysate). A: 293T. 10% SDS PAGE. TFEC antibody. TA308363 diluted at 1:1000. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TFEC antibody

WB Suggested Anti-TFEC Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

TFEC antibody

AP08822PU-N staining TFEC at 5 µg/ml in paraffin-embedded Spleen by Immunohistochemistry. Goat IgG Aff - Purified Ms, Rt E, P
50 µg / €470.00
  Acris Antibodies GmbH

TFEC antibody

Western Blot analysis of TFEC expression in transfected 293T cell line by TFEC monoclonal antibody (M08), clone 4F11.

Lane 1: TFEC transfected lysate(22.7 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 4F11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TFEC antibody

TFEC polyclonal antibody ( Cat # PAB6162 ) staining ( 1 µg/ml ) of human testis lysate ( RIPA buffer, 30 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

TFEC antibody

TFEC Goat Ms, Rt E
0.1 mg / €390.00
  Abnova Taiwan Corp.

TFEC antibody

Human Jurkat; WB Suggested Anti-TFEC Antibody Titration: 0.2-1 ug/ml. Positive Control: Jurkat cell lysate; TFEC antibody - N-terminal region (ARP32279_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

TFEC antibody

NB 100-1031 staining (1µg/ml) of Human Testis lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TFEC (full length, N-term HIS tag, transcript variant 2)

TFEC Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

TFEC

TFEC Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

TFEC

TFEC Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

TFEC

TFEC Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TFEC overexpression lysate

TFEC overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

14 Item(s)

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