TFPI antibody

Principal name

TFPI antibody

Alternative names for TFPI antibody

Tissue factor pathway inhibitor, TFPI1, LACI, EPI, Lipoprotein-associated coagulation inhibitor, Extrinsic pathway inhibitor

SwissProt ID

O54819 (Mouse), P10646 (Human), P19761 (Rabit), Q02445 (Rat)

Gene ID

7035 (TFPI), 987035 (actA)

Available reactivities

Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Mouse, Sheep, Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TFPI antibody

This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq]. Transcript Variant: This variant (2) uses an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in a protein (isoform b precursor) with a shorter and distinct C-terminus compared to isoform a precursor. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

1. Enjyoji, K.-I., Emi, M., Mukai, T., Imada, M., Leppert, M. L., Lalouel, J. M., Kato, H.Human tissue
factor pathway inhibitor (TFPI) gene: complete genomic structure and localization on the genetic map of
chromosome 2q.Genomics 17: 423-428, 1993.
2. Kleesiek, K., Schmidt, M., Gotting, C., Brinkmann, T., Prohaska, W.A first mutation in the human
tissue factor pathway inhibitor gene encoding (P151L) TFPI. (Letter)Blood 92: 3976-3977, 1998.
3. Lupu, C., Zhu, H., Popescu, N. I., Wren, J. D., Lupu, F.Novel protein ADTRP regulates TFPI
expression and function in human endothelial cells in normal conditions and in response to
androgen.Blood 118: 4463-4471, 2011.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TFPI antibody

Western blot analysis of extracts of various cell lines, using TFPI antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

TFPI antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-TFPI mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805999) Mouse IgG1 OTI5H5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

TFPI antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-TFPI mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA806052) Mouse IgG2a OTI4H9 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

TFPI (C-term) antibody

TA302625 staining (0.3µg/ml) of Hela lysate (RIPA buffer, 35µg total protein cells per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TFPI (29-44) antibody

Anti-TFPI antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. Mouse IgG n.a Purified Hu E, P, WB
50 µg / €345.00
  OriGene Technologies, Inc.

TFPI antibody

Western blot analysis of TFPI in rat small intestine tissue lysate with TFPI antibody at 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TFPI antibody

Immunohistochemical staining of human colon shows distinct cytoplasmic positivity in endothelium.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only. Rabbit IgG Purified Hu E, ICC/IF, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

TFPI antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TFPI (RC219033, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TFPI. Mouse IgG1 OTI1E1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

TFPI antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TFPI (RC219033, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TFPI. Mouse IgG1 OTI3c2 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

TFPI antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-TFPI mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA806051) Mouse IgG1 OTI5A2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

TFPI antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TFPI (RC219033, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TFPI. Mouse IgG1 OTI2B10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

TFPI antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-TFPI mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA806306) Mouse IgG1 OTI3B1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

TFPI antibody

TFPI Goat Purified Hu, Mky WB
0.1 mg / €690.00
  Acris Antibodies GmbH

TFPI antibody

TFPI Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

TFPI antibody

Western Blot analysis of TFPI expression in transfected 293T cell line (H00007035-T01) by TFPI MaxPab polyclonal antibody.

Lane 1: TFPI transfected lysate(33.44 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

TFPI antibody

TFPI MaxPab rabbit polyclonal antibody. Western Blot analysis of TFPI expression in mouse liver. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

TFPI antibody

TFPI Mouse IgG2a 2E5 Purified Hu E
50 µg / €370.00
  Abnova Taiwan Corp.

TFPI antibody

TFPI Mouse IgG2a 2E5 Ascites Hu E
0.2 ml / €370.00
  Abnova Taiwan Corp.

TFPI antibody

TFPI Mouse IgG Hu E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

TFPI antibody

TFPI Sheep Hu E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

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