TFR2 antibody

Principal name

TFR2 antibody

Alternative names for TFR2 antibody

Transferrin receptor protein 2

SwissProt ID

B2GUY2 (Rat), Q9JKX3 (Mouse), Q9UP52 (Human)

Gene ID

7036 (TFR2), 50765 (Tfr2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TFR2 antibody

This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. 
Function: Mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. 
Cellular Location: Cell membrane; Single-pass type II membrane protein. 
Tissue Location: Predominantly expressed in liver. While the alpha form is also expressed in spleen, lung, muscle, prostate and peripheral blood mononuclear cells, the beta form is expressed in all tissues tested, albeit weakly.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TFR2 antibody

Anti-TFR2 mouse monoclonal antibody (TA504563) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TFR2(RC220060). Mouse IgG2a OTI2B4 Purified Hu, Mky, Ms, Rt F, ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

TFR2 antibody

Anti-TFR2 mouse monoclonal antibody (TA504592) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TFR2(RC220060). Mouse IgG2a OTI1B1 Purified Hu, Mky, Ms F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

TFR2 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TFR2 (RC220060, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TFR2. Mouse IgG1 OTI1D8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

TFR2 (C-term) antibody

Western blot analysis using TFR2 Antibody (C-term) Cat.-No AP54229PU-N in NCI-H292, K562 cell line lysates (35ug/lane). This demonstrates the TFR2 antibody detected the TFR2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TFR2 antibody

TFR2 Rabbit IgG Aff - Purified Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TFR2

TFR2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

TFR2 overexpression lysate

TFR2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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