TGF-alpha (TGFA) antibody

Principal name

TGF-alpha (TGFA) antibody

Alternative names for TGF-alpha (TGFA) antibody

Transforming growth factor alpha, ETGF, EGF-like TGF, TGF type 1

SwissProt ID

P01134 (Rat), P01135 (Human), P48030 (Mouse), P98135 (Sheep), P98138 (Rabit), Q06922 (Pig)

Gene ID

7039 (TGFA), 24827 (Tgfa)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Bov (Bovine), Can (Canine), Hst (Hamster), Rb (Rabbit), Ze (Zebrafish), Mky (Monkey), Chk (Chicken), Por (Porcine)

Available hosts

Rabbit, Sheep, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Neutralisation (NEUT), ELISA (detection) (E(detection)), Functional assay (FN), Flow Cytometry (F)

Background of TGF-alpha (TGFA) antibody

Transforming growth factor alpha (TGF-α) is upregulated in some human cancers. It is produced in macrophages, brain cells, and keratinocytes, and induces epithelial development. It is closely related to EGF, and can also bind to the EGF receptor with similar effects . TGFα stimulates neural cell proliferation in the adult injured brain.1 Transforming growth factor alpha gene (TGFA) maps to human chromosome 2 close to the breakpoint of the t(2;8) variant translocation in Burkitt lymphoma.2 Synthetic TGF-alpha was as active as murine epidermal growth factor in binding to the epidermal growth factor receptor and in stimulation of anchorage-dependent and of anchorage-independent growth of normal indicator cells in culture. Synthetic TGF-alpha stimulated plasminogen activator production in A 431 and HeLa cells; the stimulation was similar to that induced by epidermal growth factor. Furthermore, synthetic human TGF-alpha showed similar immunoreactivity when compared with rat TGF-alpha. Thus, the 50-amino acid TGF-alpha is likely to be the bioactive principle produced and secreted by tumor cell lines.3

General readings

1.In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain. Proc Natl Acad Sci USA. 2000 Dec 19; 97(26): 14686-91;
2、Brissenden, J. E., Derynck, R., Francke, U. Transforming growth factor alpha gene (TGFA) maps to human chromosome 2 close to the breakpoint of the t(2;8) variant translocation in Burkitt lymphoma. Cytogenet. Cell Genet. 40: 589-only, 1985.
3、Tam, J. P., Scheikh, M. A., Solomon, D. S., Ossowski, L. Efficient synthesis of human type alpha transforming growth factor: its physical and biological characterization. Proc. Nat. Acad. Sci. 83: 8082-8086, 1986.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TGF-alpha (TGFA) antibody

Formalin-paraffin human Testicular Carcinoma Stained with TGF alpha MAb (SPM542) Mouse IgG1 SPM542 Purified Hu, Rb, Ze F, ICC/IF, P
0.2 mg / €390.00
  Acris Antibodies GmbH

TGF-alpha (TGFA) antibody

Formalin-paraffin human Testicular Carcinoma Stained with TGF alpha MAb (SPM542) Mouse IgG1 SPM542 Purified Hu, Rb, Ze F, ICC/IF, P
0.1 mg / €320.00
  Acris Antibodies GmbH

TGF-alpha (TGFA) antibody

Formalin-paraffin human Testicular Carcinoma Stained with TGF alpha MAb (SPM542) Mouse IgG1 SPM542 Purified Hu, Rb, Ze F, ICC/IF, P
20 µg / €160.00
  Acris Antibodies GmbH

TGF-alpha (TGFA) antibody

Western blot analysis of extracts from COS7 cells, using TGF alpha antibody (#TA314615).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TGF-alpha (TGFA) antibody

Western blot analysis using recombinant human TGF. Rabbit Purified Hu E, NEUT, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TGF-alpha (TGFA) antibody

Predicted cell location: Cytoplasm. Positive control: Human colon and thyroid cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using TGFA antibody at dilution 1/60, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TGF-alpha (TGFA) antibody

This antibody stained formalin-fixed, paraffin-embedded sections of human breast invasive ductal carcinoma.  The recommended concentration is 0.5 ug/ml with a two-hour incubation at room temperature.  An HRP-labeled polymer detection system was used with a DAB chromogen.  Heat induced antigen retrieval with a pH 6.0 Sodium Citrate buffer is recommended.  Optimal concentrations and conditions may vary. Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TGF-alpha (TGFA) antibody

Western blot analysis on COS7 cell lysate using TGF alpha Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TGF-alpha (TGFA) antibody

TGF-alpha (TGFA) Mouse IgG1 MF9 Purified Bov, Hu, Ms, Rt C, F, ICC/IF, IP, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

TGF-alpha (TGFA) antibody

TGF-alpha (TGFA) Mouse IgG1 MF9 Purified Bov, Hu, Ms, Rt C, F, ICC/IF, IP, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

TGF-alpha (TGFA) antibody

TGF-alpha (TGFA) Mouse IgG1 MF9 Purified Bov, Hu, Ms, Rt C, F, ICC/IF, IP, WB
20 µg / €160.00
  Acris Antibodies GmbH

TGF-alpha (TGFA) antibody

TGF-alpha (TGFA) Mouse IgG1 1E8-G6 Purified Hu, Rb, Ze C, F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

TGF-alpha (TGFA) antibody

TGF-alpha (TGFA) Mouse IgG1 1E8-G6 Purified Hu, Rb, Ze C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

TGF-alpha (TGFA) antibody

TGF-alpha (TGFA) Mouse IgG1 1E8-G6 Purified Hu, Rb, Ze C, F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

TGF-alpha (TGFA) antibody

TGF-alpha (TGFA) Mouse IgG1 TG86 Purified Hu, Rb, Ze F, ICC/IF, IP, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

TGF-alpha (TGFA) antibody

TGF-alpha (TGFA) Mouse IgG1 TG86 Purified Hu, Rb, Ze F, ICC/IF, IP, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

TGF-alpha (TGFA) antibody

TGF-alpha (TGFA) Mouse IgG1 TG86 Purified Hu, Rb, Ze F, ICC/IF, IP, WB
20 µg / €160.00
  Acris Antibodies GmbH

TGF-alpha (TGFA) antibody

TGF-alpha (TGFA) Mouse IgG1 P/T1 Purified Hu, Rb, Ze F, ICC/IF, IP, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

TGF-alpha (TGFA) antibody

TGF-alpha (TGFA) Mouse IgG1 P/T1 Purified Hu, Rb, Ze F, ICC/IF, IP, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

TGF-alpha (TGFA) antibody

TGF-alpha (TGFA) Mouse IgG1 P/T1 Purified Hu, Rb, Ze F, ICC/IF, IP, WB
20 µg / €160.00
  Acris Antibodies GmbH

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