TGFBR3 antibody

Principal name

TGFBR3 antibody

Alternative names for TGFBR3 antibody

TGF-beta receptor type III, TGFR-3, Betaglycan, Transforming growth factor beta receptor III

SwissProt ID

O88393 (Mouse), P26342 (Rat), P35054 (Pig), Q03167 (Human)

Gene ID

7049 (TGFBR3)

Available reactivities

Hu (Human), Chk (Chicken), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Sheep, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Flow Cytometry (F)

Background of TGFBR3 antibody

Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. There are 3 forms encoded by separate genes TGFB1, TGFB2, and TGFB3. The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins. In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), type III (TGF beta III receptor) has been identified. It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form. It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems. TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling. Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration. Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2. These results support a model where TGF beta III receptor localizes transformation in the heart and plays an essential, nonredundant role in TGF beta signaling. TGF beta III receptor, or beta glycan, can function as an inhibin coreceptor with ActRII. TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor. Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII. TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone.

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TGFBR3 antibody

Sample (30 ug of whole cell lysate). A: THP-1. 7.5% SDS PAGE. TA308670 diluted at 1:1000. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TGFBR3 antibody

Immunofluorescence analysis of HuvEc cells, using TGF ß Receptor III antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

TGFBR3 antibody

Immunohistochemical staining of extraembryonic membranes from stage 16 chick embryos using TGFbetaIII receptor antibody. Sheep IgG Purified Chk IP, P, WB
0.25 mg / €360.00
  Acris Antibodies GmbH

TGFBR3 (644-850) antibody

Human Spleen (formalin-fixed, paraffin-embedded) stained with TGFB3 antibody AP22753PU-N followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Aff - Purified Hu P
250 µl / €470.00
  Acris Antibodies GmbH

TGFBR3 antibody

TGFBR3 Goat Hu WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

TGFBR3 antibody

TGFBR3 Goat Hu E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

TGFBR3 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TGF beta Receptor III (Ab-842) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
50 µg / €205.00
  Assay Biotech

TGFBR3 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TGF beta Receptor III (Ab-842) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €310.00
  Assay Biotech

TGFBR3 antibody

Immunofluorescence analysis of HuvEc cells, using TGF beta Receptor III Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
50 µg / €205.00
  Assay Biotech

TGFBR3 antibody

Immunofluorescence analysis of HuvEc cells, using TGF beta Receptor III Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
0.1 mg / €310.00
  Assay Biotech

TGFBR3 antibody

Western Blot: TGF beta Receptor III Antibody [27030002] - Samples: Lane 1, Marker [kDa]: 250, 130, 95, 72, 55, 36, 28, 17, 11  Lane 2, RT-4 Lane 3, U-251MG sp  Lane 4, Human Plasma  Lane 5, Liver  Lane 6, Tonsil ,  Target weight [kDa]:   93    Validation score: 2   Validation description: Supportive - Band of predicted size in kDa (+/-20%) with additional bands present. Rabbit Hu E, P, WB
50 µg / €500.00
  Novus Biologicals Inc.

TGFBR3 antibody

Immunohistochemistry: TGFbeta RII Antibody [NBP1-19434] -  TGFbeta RII Antibody [NBP1-19434] - paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

TGFBR3 antibody

Immunohistochemistry-Paraffin: TGF beta Receptor III Antibody [NBP1-89988] Immunohistochemical staining of human testis shows strong cytoplasmic positivity in Leydig cells and weak staining in cells of seminiferus ducts. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

ELISA Kits

Catalog No.    

OmniKine™ Human TGFβ-R3 ELISA Kit

OmniKine™ Human TGFβ-R3 ELISA Kit  
96 Tests / €410.00
  Assay Biotech

Lysates

Catalog No.    

TGFBR3 overexpression lysate

TGFBR3 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

15 Item(s)

per page
  • LinkedIn