TGN38 antibody

Principal name

TGN38 antibody

Alternative names for TGN38 antibody

Ttgn1, Golgi Marker, FocusOn119 (Tgoln2, Tgoln1), Trans-Golgi network integral membrane protein TGN38

SwissProt ID

P19814 (Rat)

Gene ID

192152 (Tgoln1)

Available reactivities

Rt (Rat), Ms (Mouse)

Available hosts

Mouse, Rabbit, Sheep

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), Frozen Sections (C), Immunoelectron Microscopy (EM)

Background of TGN38 antibody

The trans-Golgi network (TGN) is part of the secretory pathway of eukaryotic cells which is distinct from the Golgi stack. The TGN is important in the later stages of protein secretion where it seems to play a key role in the sorting and targeting of secreted proteins to the correct destination. Some surface receptors recycle between the cell surface and the TGN, suggesting that the TGN is also important in endocytic pathways.
TGN38 and TGN46, an isoform of the former, are integral membrane proteins which are predominantly localized to the TGN in NRK cells but which can also be observed at the cell surface. Complexes which include TGN38, low molecular weight G proteins and p62 are required for the formation of TGN-derived vesicles. This requirement has lead people to believe that TGN38 is important in the trafficking of proteins from the TGN to the cell surface. Brefeldin A causes the contents of the Golgi stack to be redistributed into the endoplasmic reticulum while the TGN collapse upon the microtubule organizing center. This makes immunofluorescence detection of TGN38 following brefeldin A treatment a useful tool for the discrimination of the TGN from the Golgi stack.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TGN38 (Extracell. Dom) antibody

TGN38 Rabbit Serum Ms, Rt ICC/IF, WB
0.1 ml / €330.00
  Acris Antibodies GmbH

TGN38 (Extracell. Dom) antibody

Rabbit anti-TGN38 Antibody Cat.-No AP32689PU-N on Raw 204.4 (Left), F(ab’)2 Goat anti rabbit IgG (H+L)-FITC conjugated secondary antibody (R1410F, 1/100). Cells were fixed in 1% PFA, permeabilized in 0.25%Triton X 100 in PBS, blocked in 1% BSA in PBS. Rabbit Serum Ms, Rt EM, ICC/IF, WB
0.1 ml / €300.00
  Acris Antibodies GmbH

TGN38 (Extracell. Dom) antibody

Immunofluorescence staining of TGN38 in 3% paraformaldehyde-fixed NRK cells using Sheep anti-Rat TGN38 Antibody Serum Cat.-No AP32691SU-N at 1/100 dilution. Secondary antibody was Donkey anti-Sheep Alexa Fluor 488. Sheep Serum Ms, Rt C, ICC/IF, WB
0.1 ml / €300.00
  Acris Antibodies GmbH

TGN38 antibody

TGN38 Sheep Ms, Rt ICC/IF, P, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

TGN38 antibody

TGN38 Rabbit Ms, Rt C, ICC/IF, P, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

5 Item(s)

per page
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