TGS1 antibody

Principal name

TGS1 antibody

Alternative names for TGS1 antibody

HCA137, NCOA6IP, PIMT, Trimethylguanosine synthase homolog

SwissProt ID

P85107 (Rat), Q923W1 (Mouse), Q96RS0 (Human)

Gene ID

96764 (TGS1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Chk (Chicken), African clawed frog

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TGS1 antibody

Nuclear receptor coactivators participate in the transcriptional activation of specific genes by nuclear receptors. A new nuclear receptor coactivator-interacting protein, designated PIMT, was identified from a human liver cDNA library by using the coactivator peroxisome proliferator-activated receptor-interacting protein (PRIP) as bait in a yeast 2-hybrid screen. The PIMT cDNA encodes an 852-amino acid protein containing a 9-amino acid methyltransferase motif I (VVDAFCGVG) and an invariant segment (GXXGXXI) found in K-homology motifs of many RNA-binding proteins. Northern blot analysis demonstrated ubiquitous expression of a 3.2-kb PIMT transcript, with highest expression in heart, skeletal muscle, kidney, liver, and placenta. Immunofluorescence studies showed that the PIMT and PRIP proteins are colocalized in the nucleus. PIMT binds 5-adenosyl-L-methionine, the methyl donor for the methyltransfer reaction, and it also binds RNA, suggesting that it is an RNA methyltransferase.

General readings

Zhu Y. et al. Proc Natl Acad Sci U S A 2001 98(18):10380-5.

9 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TGS1 antibody

TGS1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

TGS1 antibody

Detection limit for recombinant GST tagged NCOA6IP is approximately 0.3ng/ml as a capture antibody. Mouse IgG1 3F1 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

TGS1 antibody

Human HepG2; WB Suggested Anti-TGS1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: HepG2 cell lysate; TGS1 antibody - middle region (ARP48923_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified African clawed frog, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

TGS1 antibody

Immunohistochemistry-Paraffin: PIMT Antibody [NB100-2595] - Please see notes section Rabbit Aff - Purified Hu IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

TGS1 antibody

TGS1 Rabbit Aff - Purified Hu WB
0.1 mg / €340.00
  Novus Biologicals Inc.

TGS1 antibody

Western Blot: PIMT Antibody [NBP1-54942] - This Anti-TGS1 antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms WB
50 µg / €440.00
  Novus Biologicals Inc.

TGS1 antibody

Immunohistochemistry-Paraffin: PIMT Antibody [NBP1-92271] - Immunohistochemical staining of human kidney shows strong nuclear positivity in tubular and glomerular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TGS1

TGS1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TGS1

TGS1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

9 Item(s)

per page
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