Thioredoxin-2 / TRX2 antibody

Principal name

Thioredoxin-2 / TRX2 antibody

Alternative names for Thioredoxin-2 / TRX2 antibody

TXN2, mitochondrial Thioredoxin

SwissProt ID

P97493 (Mouse), P97615 (Rat), Q95108 (Bovin), Q99757 (Human)

Gene ID

25828 (TXN2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Dros (Drosophila), Ze (Zebrafish), African clawed frog, Xen (Xenopus), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Functional assay (FN), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Thioredoxin-2 / TRX2 antibody

Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1. Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

General readings

Wang Z., et al. (2007). Rapid Commun Mass Spectrom. 21(22):3658-66.
Zhang H., et al. (2007). Arch Biochem biophys. 1;465(1):119-26.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Thioredoxin-2 / TRX2 antibody

WB Suggested Anti-TXN2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Transfected 293T Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Thioredoxin-2 / TRX2 antibody

WB Suggested Anti-TXN2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Transfected 293T Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Thioredoxin-2 / TRX2 (C-term) antibody

Western blot analysis of anti-Trx2-I151 Pab (Cat. #AP11339PU-N) in 293 cell line lysate (35ug/lane). Trx2-I151 (arrow) was detected using the purified Pab (1:36 dilution). Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Thioredoxin-2 / TRX2 antibody

Immunoprecipitation analysis of 293T cell lysates. Lane 1 : Input and lane 2 : Precipitates. Immunoblotting with TXN2 monoclonal antibody, clone 4C5 ( Cat # MAB0723 ). Mouse IgG2b 4C5 Hu IP
0.1 ml / €390.00
  Abnova Taiwan Corp.

Thioredoxin-2 / TRX2 antibody

Immunoprecipitation analysis of 293T cell lysates. Lane 1 : Input and lane 2 : Precipitates. Immunoblotting with TXN2 monoclonal antibody, clone 71G4 ( Cat # MAB0724 ). Mouse IgG1 71G4 Hu IP
0.1 ml / €390.00
  Abnova Taiwan Corp.

Thioredoxin-2 / TRX2 antibody

Western blot analysis of TXN2 polyclonal antibody ( Cat # PAB2468 ) in 293 cell line lysate ( 35 µg/lane ) . TXN2 ( arrow ) was detected using the purified polyclonal antibody ( 1 : 36 dilution ) . Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

Thioredoxin-2 / TRX2 antibody

Transfected 293T; WB Suggested Anti-TXN2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Transfected 293T; TXN2 antibody - middle region (ARP54909_P050) in Transfected 293T cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Dros, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

Thioredoxin-2 / TRX2 antibody

Transfected 293T; WB Suggested Anti-TXN2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Transfected 293T; TXN2 antibody - middle region (ARP54910_P050) in Transfected 293T cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

Thioredoxin-2 / TRX2 antibody

Western blot analysis of Thioredoxin 2 expression in HeLa (A); mouse liver (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Thioredoxin-2 / TRX2 antibody

Western blot analysis of Thioredoxin 2 expression in HeLa (A); mouse liver (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Thioredoxin-2 / TRX2 antibody

Western blot analysis of Thioredoxin 2 expression in HeLa (A); mouse liver (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Thioredoxin-2 / TRX2 antibody

Western Blot: thioredoxin 2 Antibody [NBP1-54672] - This Anti-TXN2 antibody was used in Western Blot of Transfected 293T tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Bov, Can, Chk, Dros, Hu, Ms, Rt, Xen, Ze WB
50 µg / €440.00
  Novus Biologicals Inc.

Thioredoxin-2 / TRX2 antibody

Western Blot: thioredoxin 2 Antibody [NBP1-54673] - This Anti-TXN2 antibody was used in Western Blot of Transfected 293T tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Thioredoxin-2 / TRX2 antibody

Immunohistochemistry-Paraffin: Thioredoxin 2 Antibody [NBP1-92499] - Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Thioredoxin-2 / TRX2

Thioredoxin-2 / TRX2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Thioredoxin-2 / TRX2

Thioredoxin-2 / TRX2 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €299.00
  OriGene Technologies, Inc.

Thioredoxin-2 / TRX2 (60-166)

Thioredoxin-2 / TRX2 Human Purified ≥ 95 by SDS PAGE E. coli
0.5 mg / €1,000.00
  Acris Antibodies GmbH

Thioredoxin-2 / TRX2 (60-166)

Thioredoxin-2 / TRX2 Human Purified ≥ 95 by SDS PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

Thioredoxin-2 / TRX2

Thioredoxin-2 / TRX2 Human
0.1 mg / €450.00
  Abnova Taiwan Corp.

Thioredoxin-2 / TRX2

Thioredoxin-2 / TRX2 Human
0.5 mg / €330.00
  Abnova Taiwan Corp.

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