THOC4 / ALY antibody

Principal name

THOC4 / ALY antibody

Alternative names for THOC4 / ALY antibody

THO4, BEF, THO complex subunit 4, Ally of AML-1 and LEF-1, Transcriptional coactivator Aly/REF, bZIP-enhancing factor BEF

SwissProt ID

O08583 (Mouse), Q86V81 (Human)

Gene ID

10189 (ALYREF)

Available reactivities

Hu (Human), Xen (Xenopus), Bov (Bovine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoelectron Microscopy (EM), Flow Cytometry (F)

Background of THOC4 / ALY antibody

Pre-mRNA splicing plays an important role in regulation of gene expression. During the splicing process, specific proteins are recruited to the mRNA and assembled into a complex of mRNA-protein near the exon-exon junction. This complex is termed the mRNA-protein complex (mRNP) or the exon-exon junction complex. The proteins that are found in this complex include: Y14, magoh, Aly/REF, RNPS1, Upf3, and DEK.1-5 Aly (also known as mREF1-I) is the mammalian homologue of the yeast mRNA export factor Yra1p.6-7 It is a 233 amino acid RNAbinding protein that contains a RNA-binding domain and is recruited to the mRNP complexes during the splicing. Excess of recombinant expression of Aly in the cells increases both the rate and efficiency of spliced and unspliced mRNA export (in vivo) from the nucleus to the cytoplasm. In contrast to the Y14 protein, Aly is dissociated from the mRNAs after the export to the cytoplasm.1, 5-6

General readings

Strasser,K., (2002) Nature 417 (6886), 304-308

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

THOC4 / ALY antibody

Sample (30 ug of whole cell lysate). A: Molt-4 . 12% SDS PAGE. TA307902 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

THOC4 / ALY antibody

Western blot analysis of extracts from LOVO cells and K562 cells, using THOC4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

THOC4 / ALY antibody

Predicted cell location: Nucleus,Cytoplasm. Positive control: Human lymphoma and liver cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human lymphoma tissue using ALYREF antibody at dilution 1/15, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

THOC4 / ALY (Center) antibody

THOC4 Antibody (Center) (AP54241PU-N) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the THOC4 antibody detected the THOC4 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

THOC4 / ALY antibody

THOC4 / ALY Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

THOC4 / ALY antibody

THOC4 / ALY Mouse IgG2a 2G8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

THOC4 / ALY antibody

THOC4 / ALY Mouse IgG1 11G5 Hu E, ICC/IF, IP, WB
0.1 ml / €560.00
  Abnova Taiwan Corp.

THOC4 / ALY antibody

Human Lung; THOC4 antibody - N-terminal region (ARP43055_T100) in Human Lung cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Chk, Hu, Ms, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

THOC4 / ALY antibody

ALY Antibody [11G5] - ChIP grade Mouse IgG1 11G5 Purified Hu, Ms, Xen E, EM, F, ICC/IF, IP, P, WB
0.1 ml / €400.00
  Immuquest

THOC4 / ALY antibody

ALY Antibody [11G5] - ChIP grade Mouse IgG1 11G5 Purified Hu, Xen E, EM, F, ICC/IF, IP, P, WB
50 µl / €360.00
  Immuquest

THOC4 / ALY antibody

HeLa cell extract was separated by SDS-PAGE and probed with Monoclonal Anti-ALY  (0.4 ìg/mL, lane 1) followed by Goat Anti-Mouse, Peroxidase conjugate (Cat. No. A2304, lane 1,2) and a chemiluminescent substrate. Mouse IgG1 11G5 Purified Hu, Xen E, ICC/IF, IP, WB
50 µl / €360.00
  Novus Biologicals Inc.

THOC4 / ALY antibody

Immunohistochemistry: ALY Antibody [NBP1-33598] - Immunohistochemical analysis of ALY on paraffin-embedded SAS xenograft, using NBP1-33598. Rabbit IgG Hu ICC/IF, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

THOC4 / ALY antibody

Immunohistochemistry-Paraffin: Aly Antibody [NBP1-90179] - Immunohistochemical staining of human testis shows strong nuclear positivity in cells in seminiferus tubules. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

THOC4 / ALY

THOC4 / ALY Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

THOC4 / ALY

THOC4 / ALY Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

15 Item(s)

per page
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