THOC7 antibody

Principal name

THOC7 antibody

Alternative names for THOC7 antibody

THO complex subunit 7 homolog, fSAP24, hTREX30, NIF3L1BP1, Functional spliceosome-associated protein 24, Ngg1-interacting factor 3-like protein 1-binding protein 1, NIF3L1-binding protein 1

SwissProt ID

Q6I9Y2 (Human)

Gene ID

80145 (THOC7)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of THOC7 antibody

THOC7 is a component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mR and not with unspliced pre-mR. It is recruited to spliced mRs by a transcription-independent mechanism. Binds to mR upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mR where it functions in mR export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRs and infectious virus production. The recruitment of the TREX complex to the intronless viral mR occurs via an interaction between KSHV ORF57 protein and ALYREF/THOC4.

General readings

El Bounkari O., et al. (2009) FEBS Lett. 583 (1), 13-18

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

THOC7 antibody

Host: Rabbit; Target Name: THOC7; Sample Tissue: HepG2 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

THOC7 antibody

Immunohistochemistry-Paraffin: THOC7 Antibody [NBP1-82076] - Immunohistochemical staining of human cerebral cortex shows moderate nuclear positivity in neuronal cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

THOC7

THOC7 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

THOC7 (1-204, His-tag)

THOC7 Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

THOC7 (1-204, His-tag)

THOC7 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

THOC7

THOC7 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

THOC7

THOC7 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

7 Item(s)

per page
  • LinkedIn