THRA / ERBA1 antibody

Principal name

THRA / ERBA1 antibody

Alternative names for THRA / ERBA1 antibody

Thyroid hormone receptor alpha, THRA1, THRA2, C-erbA-alpha, c-erbA-1, EAR-7, EAR7, NR1A1, Nuclear receptor subfamily 1 group A member 1

SwissProt ID

P10827 (Human)

Gene ID

7067 (THRA)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), Mky (Monkey), Eq (Equine), Hst (Hamster), Sh (Sheep)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of THRA / ERBA1 antibody

Thyroid hormone nuclear receptors (TRs) are ligand-dependent transcription factors which regulate growth, differentiation and development and represent members of the steroid/retinoic acid superfamily. The two genes encoding TRs identified to date, TRα and TRβ, have been mapped to human chromosomes 17 and 3, respectively. TRs bind to thyroid hormone response elements (TREs) with half-site binding motifs in the orientation of palindromes, direct repeats or inverted palindromes. The affinities of binding are both variable and influenced differentially by 3,5,3'-triiodo-L-thyronine (T3). Transcriptional regulation by TRs is also modulated by heterodimerization with TR nuclear accessory proteins, the most extensively characterized of which are the retinoid X receptors (RXRα, RXRβ and RXRγ). To a certain extent, this activity is regulated by differential phosphorylation of TRs. Thus, not only are the biological activities of TRs regulated by heterodimerization with RXRs, but in addition, the gene regulatory activities of TRs are linked to other hormonal pathways. TRα1 can display both a nuclear and undefined cytoplasmic location, and is the only TR that is imported into the mitochondrial matrix.

General readings

Nishiyama K, Baba S, Yamada T, Matsushita A, Natsume H, Nakano K, Sasaki S, Nakamura H.
Embryonic lethal effect of expressing a dominant negative mutant human thyroid hormone receptor alpha1 in mice.
Endocr J. 2003 Oct;50(5):561-70.
PMID: 14614212

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

THRA / ERBA1 antibody

  Goat Polyclonal Antibody against THRA  
TA303267 (0.5µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

THRA / ERBA1 antibody

  Rabbit polyclonal antibody to TR Alpha (thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian))  
Sample (30 ug of whole cell lysate). A: JurKat. 10% SDS PAGE. TA308957 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, IP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

THRA / ERBA1 (a1/a2) antibody

  Mouse Anti-Thyroid Hormone Receptor, a1/a2-Isotype Antibody  
Western blot of hippocampal lysate showing specific immunolabeling of the ~50k TR-α1 and the ~58k TR-α2 protein. Mouse IgG1 2103 Aff - Purified Can, Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

THRA / ERBA1 (a1/a2) antibody

  Mouse Anti-Thyroid Hormone Receptor, a1/a2-Isotype Antibody  
Western blot of hippocampal lysate showing specific immunolabeling of the ~50k TR-α1 and the ~58k TR-α2 protein. Mouse IgG2a 1718 Aff - Purified Can, Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

THRA / ERBA1 (Alpha-2) antibody

  Mouse Anti-Thyroid Hormone Receptor, a2-Isotype Antibody  
Western blot of hippocampal lysate showing specific immunolabeling of the ~58k TR-α2 protein. Mouse IgG1 1330 Aff - Purified Bov, Can, Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

THRA / ERBA1 antibody

  Rabbit polyclonal Thyroid Hormone Receptor a antibody  
Western blot analysis of extracts from SKOV3 cells, using Thyroid Hormone Receptor a antibody (#TA313020).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

THRA / ERBA1 antibody

  Rabbit polyclonal anti-THRA antibody  
WB using Anti-THRA antibody shows detection of purified recombinant THRA (lane 1) and THRA present in a 293 cell lysate after transient transfection with THRA (lane 3). No staining is evident in lysates from mock-transfected 293 cells (lane 2). Endogenous THRA is not detected in mouse brain whole cell lysate (lane 4). Nuclear extracts may be required to detect endogenous THRA as the protein localizes within the nucleus. The band at ~55 kDa, indicated by the arrowhead, corresponds to THRA. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €356.00
  OriGene Technologies, Inc.

THRA / ERBA1 (Ligand bdg. Dom.) antibody

  Rabbit Polyclonal Anti-THRA Antibody (Ligand-binding Domain)  
Anti-THRA antibody IHC of human surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bov, Can, Eq, Hst, Hu, Mky, Ms, Por, Rb, Rt, Sh P
50 µg / €400.00
  OriGene Technologies, Inc.

THRA / ERBA1 (Ligand bdg. Dom.) antibody

  Rabbit Polyclonal Anti-THRA Antibody (Ligand-binding Domain)  
Anti-THRA antibody IHC of human surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Eq, Hst, Hu, Mky, Rt P
50 µg / €400.00
  OriGene Technologies, Inc.

THRA / ERBA1 antibody

  Rabbit Polyclonal Anti-THRA Antibody  
Gel: 8%SDS-PAGE,Lysate: 40 ug,,Primary antibody: (THRA Antibody) at dilution 1/400 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

THRA / ERBA1 antibody

  Rabbit Polyclonal anti-Thyroid Hormone Receptor alpha1/alpha2 Antibody  
Human Thyroid stained with anti-Thyroid Hormone Receptor alpha1_alpha2 antibody. Rabbit Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

THRA / ERBA1 antibody

  THRA mouse monoclonal antibody, clone OTI6B7 (formerly 6B7)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY THRA (RC203210, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-THRA. Mouse IgG1 OTI6B7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

THRA / ERBA1 antibody

  THRA mouse monoclonal antibody, clone OTI5A8 (formerly 5A8)  
HEK293T cells were transfected with the pCMV6-AC-GFP control (Left lane) or pCMV6-AC-GFP  THRA (RC203210, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-THRA. Mouse IgG2a OTI5A8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

THRA / ERBA1 antibody

  THRA mouse monoclonal antibody, clone OTI7G2 (formerly 7G2)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY THRA (RC203210, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-THRA. Mouse IgG1 OTI7G2 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

THRA / ERBA1 antibody

  THRA mouse monoclonal antibody, clone OTI2A2 (formerly 2A2)  
Immunohistochemical staining of paraffin-embedded Human Ovary tissue within the normal limits using anti-THRA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805187) Mouse IgG1 OTI2A2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

THRA / ERBA1 antibody

  THRA mouse monoclonal antibody, clone OTI3E10 (formerly 3E10)  
Immunohistochemical staining of paraffin-embedded Human Ovary tissue within the normal limits using anti-THRA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805188) Mouse IgG1 OTI3E10 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

THRA / ERBA1 antibody

  THRA mouse monoclonal antibody, clone OTI5E12 (formerly 5E12)  
HEK293T cells were transfected with the pCMV6-AC-GFP control (Left lane) or pCMV6-AC-GFP  THRA (RC203210, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-THRA. Mouse IgG1 OTI5E12 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

THRA / ERBA1 antibody

  THRA mouse monoclonal antibody, clone OTI5C12 (formerly 5C12)  
HEK293T cells were transfected with the pCMV6-AC-GFP control (Left lane) or pCMV6-AC-GFP THRA (RC203210, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-THRA. Mouse IgG1 OTI5C12 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

THRA / ERBA1 (alpha-2) antibody

THRA / ERBA1 Mouse IgG1 1330 Purified Bov, Can, Hu, Ms, Rt WB
0.1 ml / €490.00
  Acris Antibodies GmbH

THRA / ERBA1 antibody

Immunohistochemistry analysis of THRA / ERBA1 Antibody (Cat.-No AP06353PU-N) in paraffin-embedded human colon carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

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