THRB / ERBA2 antibody

Principal name

THRB / ERBA2 antibody

Alternative names for THRB / ERBA2 antibody

Thyroid hormone receptor beta, THR1, NR1A2, Nuclear receptor subfamily 1 group A member 2

SwissProt ID

P10828 (Human), P18113 (Rat), P37242 (Mouse), P68306 (Chick), Q28571 (Sheep), Q9PVE4 (Danre)

Gene ID

7068 (THRB), 30607 (thrb), 21834 (Thrb)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine), Rb (Rabbit), Can (Canine), Sh (Sheep), Ze (Zebrafish), Bov (Bovine), Chk (Chicken), Eq (Equine), GP (Guinea Pig)

Available hosts

Mouse, Rabbit, Goat

Available applications

Electrophoretic Mobility Shift Assay (EMSA), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of THRB / ERBA2 antibody

THRB is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Defects in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several transcript variants have been observed for this gene, but the full-length ture of only one has been determined so far. The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several altertively spliced transcript variants encoding the same protein have been observed for this gene.

General readings

Kim JH, Park TS, Baek HS, Kim GH, Yoo HW, Park JH.
A newly identified insertion mutation in the thyroid hormone receptor-beta gene in a Korean family with generalized thyroid hormone resistance.
J Korean Med Sci. 2007 Jun;22(3):560-3.
PMID: 17596672

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

THRB / ERBA2 antibody

AP15819PU THR beta antibody staining of Human Thyroid. Rabbit Purified Can, Hu P
1 ml / €440.00
  Acris Antibodies GmbH

THRB / ERBA2 antibody

AP15819PU THR beta antibody staining of Human Thyroid. Rabbit Purified Can, Hu P

Regular Price: 0.2 ml / €200.00

Special Price: 0.2 ml / €140.00

  Acris Antibodies GmbH

THRB / ERBA2 antibody

AP15819PU THR beta antibody staining of Human Thyroid. Rabbit Purified Can, Hu P

Regular Price: 50 µl / €80.00

Special Price: 50 µl / €56.00

  Acris Antibodies GmbH

THRB / ERBA2 antibody

Staining of Zebrafish adult Heart lysate using THRB Antibody Cat.-No AP33293PU-N at 2.5 µg/ml  (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Ze E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

THRB / ERBA2 antibody

TA303268 (0.3µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

THRB / ERBA2 (N-term) antibody

Western blot of hippocampal lysate showing specific immunolabeling of the ~58k TR-β protein. Mouse IgG1 2386 Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

THRB / ERBA2 (Isoform beta-1) antibody

Western blot using affinity purified anti-THRB1 antibody shows detection of in vitro translated THRB1 (lane 2) and human thyroid stable cell line expressing THTRb1 (lane 3). No staining is evident in non transfected human thyroid cells (lane 1), over expressed THRA (lane 4) or HeLa stable cell line expressing THRA1 (lane 5). The band at ~62 kDa, indicated by the arrowheads, corresponds to THRB. Personal communication, H. Ying, NCI, Bethesda, MD Rabbit IgG Aff - Purified Hu, Ms, Rt E, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

THRB / ERBA2 antibody

Western blot analysis of extracts of various cell lines , using THRB antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

THRB / ERBA2 antibody

WB Suggested Anti-THRB Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human brain Rabbit IgG Purified Can, Eq, Hu, Ms, Rb, Rt, Sh ChIP, WB
50 µg / €325.00
  OriGene Technologies, Inc.

THRB / ERBA2 antibody

WB Suggested Anti-THRB Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: MCF7 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Por, Rb, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

THRB / ERBA2 antibody

WB Suggested Anti-THRB Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Human muscle Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

THRB / ERBA2 antibody

WB Suggested Anti-THRB Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human muscle Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

THRB / ERBA2 antibody

WB Suggested Anti-Thrb Antibody Titration: 1.25 ug/ml; Positive Control: SP2/0 cell lysate Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Por, Rt ChIP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

THRB / ERBA2 antibody

WB Suggested Anti-Thrb Antibody Titration: 0.2-1 ug/ml; Positive Control: Mouse Muscle Rabbit IgG Purified Ms, Rt ChIP, WB
50 µg / €325.00
  OriGene Technologies, Inc.

THRB / ERBA2 antibody

Western blot analysis on 293 cell lysate using THR1 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

THRB / ERBA2 (Isoform beta-1) antibody

Adult rat brain low-speed pellet immunoblot Mouse IgG2b N402/13 Supernatant Hu, Ms, Rt ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

THRB / ERBA2 antibody

Immunohistochemistry  analysis of THRB / ERBA2 Antibody (Cat.-No.: AP06354PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

THRB / ERBA2 (Isoform beta-1) antibody

Western blot using affinity purified anti-THRB1 antibody shows detection of in vitro translated THRB1 (lane 2) and human thyroid stable cell line expressing THTRb1 (lane 3). No staining is evident in non transfected human thyroid cells (lane 1), over expressed THRA (lane 4) or HeLa stable cell line expressing THRA1 (lane 5). The band at ~62 kDa, indicated by the arrowheads, corresponds to THRB. Personal communication, H. Ying, NCI, Bethesda, MD Rabbit IgG Aff - Purified Hu, Ms, Rt E, IP, WB
25 µl / €190.00
  Acris Antibodies GmbH

THRB / ERBA2 antibody

THRB / ERBA2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

THRB / ERBA2 antibody

THRB / ERBA2 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

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