Thrombospondin-2 (THBS2) antibody

Principal name

Thrombospondin-2 (THBS2) antibody

Alternative names for Thrombospondin-2 (THBS2) antibody

TSP2

SwissProt ID

P35440 (Chick), P35442 (Human), Q03350 (Mouse)

Gene ID

7058 (THBS2)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Can (Canine), Chk (Chicken)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of Thrombospondin-2 (THBS2) antibody

Thrombospondins (TSPs) are a family of homotrimeric multi-domain glycoproteins involved in modulation of cell adhesion, proliferation, and migration and have been implicated clinically in the development of atherosclerosis, angiogenesis, and oncogenesis. TSP2, a member of the thrombospondin family is a secreted protein, but is present only transiently in extracellular matrix and is rapidly internalized for degradation by fibroblasts after binding to the cell surface. It also interacts with matrix metalloproteinases (MMPs) and matrix serine proteases, such as plasminogen activator. TSP2 is reportedly controls the apoptosis-proliferation balance in endothelial cells. Although TSP2 is a potent inhibitor of angiogenesis, its N-terminal region exhibits pro-angiogenic activities mediated by beta 1 integrins. Loss of TSP2 expression is associated with local invasive behavior, tumor neovascularization, and metastasis. Decreased TSP2 expression has been correlated with malignant progression and angiogenesis in some cancers. TSP2 levels are also highly expressed in developing and healing tissues.

General readings

Expression and localization of thrombospondin-1 and -2 and their cell-surface receptor, CD36, during rat follicular development and formation of the corpus luteum.Petrik JJ et al,Biol Reprod. 2002 Nov;67(5):1522-31.
Bovine thrombospondin-2: complete comp

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Thrombospondin-2 (THBS2) antibody

Immunohistochemistry: Thrombospondin 2 Antibody - Most of the normal tissues displayed moderate cytoplasmic positivity. Lymphoid tissues were weakly stained. Malignant tissues exhibited weak to moderate cytoplasmic immunoreactivity. Single cases of colo-rectal and hepatocellular carcinoma showed strong staining. A few cases of lymphomas, endometrial and cervical cancers were negative.  Image and statement courtesy of the Human Protein Atlas (HPA). Rabbit IgG Purified Hu, Mky E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Thrombospondin-2 (THBS2) antibody

Thrombospondin-2 (THBS2) Rabbit IgG Aff - Purified Hu P, WB
0.1 mg / €290.00
  Boster Immunoleader

Thrombospondin-2 (THBS2) antibody

Western blot analysis of Thrombospondin 2 expression in A549 (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Thrombospondin-2 (THBS2) antibody

Western blot analysis of Thrombospondin 2 expression in A549 (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Thrombospondin-2 (THBS2) antibody

Western blot analysis of Thrombospondin 2 expression in A549 (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Thrombospondin-2 (THBS2) antibody

Thrombospondin-2 (THBS2) Rabbit Purified Bov, Hu E, P, WB
0.2 ml / €400.00
  Novus Biologicals Inc.

ELISA Kits

Catalog No.    

Human Thrombospondin 2 ELISA Kit

Representative Standard Curve  
96 Tests / €450.00
  Cohesion Biosciences Ltd.

Human TSP2 ELISA Kit

Human TSP2 ELISA Kit  
96 Tests / €410.00
  Boster Immunoleader

OmniKine™ Human Thrombospondin-2 ELISA Kit

OmniKine™ Human Thrombospondin-2 ELISA Kit  
96 Tests / €410.00
  Assay Biotech

THBS2 (Human) ELISA kit

THBS2 (Human) ELISA kit  
1 kit / €590.00
  Abnova Taiwan Corp.

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