Thymidine kinase 1 (TK1) antibody

Principal name

Thymidine kinase 1 (TK1) antibody

Alternative names for Thymidine kinase 1 (TK1) antibody

Thymidine kinase cytosolic, TK-1

SwissProt ID

A5D7R8 (Bovin), P04047 (Chick), P04183 (Human), P04184 (Mouse), P27158 (Rat)

Gene ID

7083 (TK1), 21877 (Tk1), 24834

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Thymidine kinase 1 (TK1) antibody

Thymidine kinase (TK) belongs to a group of enzymes such as dihydrofolate reductase, thymidylate synthase, and DNA polymerase that are involved in DNA synthesis and precursor production. Two forms have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells due to multiple regulatory mechanisms that ensure expression of these enzymes exclusively in replicating cells. TK is responsible for catalyzing the phosphorylation of thymidine, which functions as a part of the pyrimidine salvage pathway involved in DNA synthesis. The activities of enzymes such as TK are essential for the activation of several chemotherapeutically important nucleoside analogues that are administered as prodrugs.

General readings

Chang Z.F., et al. (1998) J. Biol. Chem. 273:12095-12100Kreidberg J.A., et al. (1986) Mol. Cell. Biol. 6:2903-2909

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Thymidine kinase 1 (TK1) antibody

  Rabbit polyclonal Thymidine Kinase 1 antibody  
Western blot analysis of extracts from LOVO cells, A549 cells, HepG2 cells and K562 cells, using KITH_HHV11 Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Thymidine kinase 1 (TK1) antibody

  Rabbit polyclonal KITH_HHV1C antibody  
Western blot analysis of extracts from HuvEc cells, HepG2 cells and RAW264.7 cells, using KITH_HHV1C Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Thymidine kinase 1 (TK1) antibody

  Rabbit polyclonal TK (Ab-13) antibody  
Western blot analysis of extracts from COLO205 cells, using TK (Ab-13) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Thymidine kinase 1 (TK1) antibody

  Rabbit polyclonal TK (Ser13) antibody(Phospho-specific)  
Western blot analysis of extracts from HeLa cells, treated with paclitaxel (1uM, 24hours), using TK (Phospho-Ser13) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Thymidine kinase 1 (TK1) antibody

  Rabbit polyclonal anti-OR52A4 antibody  
Western blot analysis of extracts from MCF-7 cells, using OR52A4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Thymidine kinase 1 (TK1) antibody

  Rabbit Polyclonal TK Antibody  
Western blot analysis of TK expression in COLO205 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Thymidine kinase 1 (TK1) antibody

  Rabbit anti-TK1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using TK1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Thymidine kinase 1 (TK1) (N-term) antibody

Prostate: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Thymidine kinase 1 (TK1) pSer13 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using TK (Phospho-Ser13) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

Thymidine kinase 1 (TK1) pSer13 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using TK (Phospho-Ser13) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

Thymidine kinase 1 (TK1) antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TK (Ab-13) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

Thymidine kinase 1 (TK1) antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TK (Ab-13) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

Thymidine kinase 1 (TK1) antibody

Western blot analysis of extracts from HeLa/COS7 cells, using KITH Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Assay Biotech

Thymidine kinase 1 (TK1) antibody

Western blot analysis of extracts from HeLa/COS7 cells, using KITH Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €330.00
  Assay Biotech

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Thymidine kinase 1 (TK1)

  Recombinant protein of human thymidine kinase 1, soluble (TK1), expressed in human cells  
Thymidine kinase 1 (TK1) Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Thymidine kinase 1 (TK1) (1-234, His-tag)

Thymidine kinase 1 (TK1) Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

Thymidine kinase 1 (TK1) (1-234, His-tag)

Thymidine kinase 1 (TK1) Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

TK1 overexpression lysate

TK1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tk1 (GFP-tagged) - Mouse thymidine kinase 1 (Tk1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tk1 (GFP-tagged) - Mouse thymidine kinase 1 (Tk1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tk1 (Myc-DDK-tagged) - Mouse thymidine kinase 1 (Tk1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tk1 (Myc-DDK-tagged) - Mouse thymidine kinase 1 (Tk1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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