Thymidine kinase 2 (TK2) antibody

Principal name

Thymidine kinase 2 (TK2) antibody

Alternative names for Thymidine kinase 2 (TK2) antibody

Thymidine kinase 2 mitochondrial, TK-2

SwissProt ID

O00142 (Human), Q9R088 (Mouse)

Gene ID

7084 (TK2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of Thymidine kinase 2 (TK2) antibody

Thymidine kinase-2 (TK2) is a deoxyribonucleoside kinase that phosphorylates thymidine, deoxycytidine, and deoxyuridine, and also phosphorylates antiviral and anticancer nucleoside analogs. Both recombinant and native forms of the enzyme have broad substrate specificity and complex kinetics, suggesting that it may play a role in the activation of chemotherapeutic nucleoside analogs. The highest levels of expression are observed in testis and ovary. The main supply of deoxyribonucleotides (dNTPs) for mitochondrial DNA synthesis comes from the salvage pathway initiated by deoxyguanosine kinase (DGK) and TK2. The association of mitochondrial DNA depletion with mutations in the genes encoding these 2 kinases suggests that the salvage pathway enzymes are involved in the maintenance of balanced mitochondrial dNTP pools.

General readings

Saada A., et al. (2001) Nat. Genet. 29:342-344Kit S. (1985). Thymidine kinase. Microbiol. Sci. 2 (12): 369-75.

10 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Thymidine kinase 2 (TK2) (N-term) antibody

The anti-TK2 Pab is used in Western blot to detect TK2 in HepG2 cell lysate (Lane 1) and mouse liver tissue lysate (Lane 2). Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Thymidine kinase 2 (TK2) antibody

The TK2 polyclonal antibody ( Cat # PAB4599 ) is used in Western blot to detect TK2 in mouse liver tissue lysate . Rabbit Hu, Ms E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

Thymidine kinase 2 (TK2) (C-term) antibody

Human Fetal heart; WB Suggested Anti-TK2 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Fetal Heart; TK2 antibody - C-terminal region (ARP61417_P050) in Human Fetal heart cells using Western Blot Rabbit Aff - Purified Hu P, WB
50 µg / €350.00
  AVIVA Systems Biology

Thymidine kinase 2 (TK2) antibody

Thymidine kinase 2 (TK2) Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Thymidine kinase 2 (TK2) antibody

Immunohistochemistry-Paraffin: Thymidine Kinase 2 Antibody [NBP1-92505] - Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in renal tubules. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Thymidine kinase 2 (TK2) (34-265, His-tag)

Thymidine kinase 2 (TK2) Human Purified > 85 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

Thymidine kinase 2 (TK2) (34-265, His-tag)

Thymidine kinase 2 (TK2) Human Purified > 85 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Thymidine kinase 2 (TK2)

Thymidine kinase 2 (TK2) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Thymidine kinase 2 (TK2)

Thymidine kinase 2 (TK2) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Thymidine kinase 2 (TK2)

Thymidine kinase 2 (TK2) Human
50 µg / €450.00
  Abnova Taiwan Corp.

10 Item(s)

per page
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