Thymidylate synthase (TS) antibody

Principal name

Thymidylate synthase (TS) antibody

Alternative names for Thymidylate synthase (TS) antibody

TYMS, TSase, OK/SW-cl.29

SwissProt ID

P04818 (Human), P45352 (Rat)

Gene ID

7298 (TYMS), 29261 (Tyms)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Bac (Bacteria), Mky (Monkey)

Available hosts

Mouse, Rabbit, Sheep

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), EPair for Elisa (EPair), ELISA (detection) (E(detection)), Flow Cytometry (F), Frozen Sections (C)

Background of Thymidylate synthase (TS) antibody

TYMS catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-47 CR601528.1 1-47 48-1099 X02308.1 14-1065 1100-1603 BC083512.1 1067-1570

General readings

Shahrokni A, et al., (2009) Clin Colorectal Cancer 8(4):231-4.
Henríquez-Hernández LA, et al., (2009) Oncol Rep 22(6):1425-33.
Colavito D, et al., (2009) Cancer Chemother Pharmacol 64(6):1195-200.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Thymidylate synthase (TS) antibody

  Rabbit Monoclonal anti-Thymidylate Synthase (TS) Antibody  
Human Colon Carcinoma stained with anti-Thymidylate Synthase (TS) antibody. Rabbit SP112 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Thymidylate synthase (TS) antibody

  TYMS mouse monoclonal antibody, clone OTI10F12 (formerly 10F12)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-TYMS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801551) Mouse IgG2a OTI10F12 Purified Hu P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Thymidylate synthase (TS) antibody

  TYMS mouse monoclonal antibody, clone OTI5H8 (formerly 5H8)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TYMS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801565) Mouse IgG2b OTI5H8 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Thymidylate synthase (TS) antibody

  TYMS mouse monoclonal antibody, clone OTI1B1 (formerly 1B1)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TYMS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801664) Mouse IgG1 OTI1B1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Thymidylate synthase (TS) antibody

  TYMS mouse monoclonal antibody, clone OTI3F1 (formerly 3F1)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TYMS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801677) Mouse IgG2a OTI3F1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Thymidylate synthase (TS) antibody

  TYMS mouse monoclonal antibody, clone OTI1A6 (formerly 1A6)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TYMS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801678) Mouse IgG2b OTI1A6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Thymidylate synthase (TS) antibody

  TYMS mouse monoclonal antibody, clone OTI1D6 (formerly 1D6)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TYMS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801760) Mouse IgG2a OTI1D6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Thymidylate synthase (TS) antibody

  TYMS mouse monoclonal antibody, clone OTI1A3 (formerly 1A3)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TYMS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801761) Mouse IgG1 OTI1A3 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Thymidylate synthase (TS) antibody

HeLa cells were stained with monoclonal anti-TYMS antibody (Green). Nucleus and Actin were stained by Phalloidin-TRITC (Red) or Hoechst 33342 (Blue). Mouse IgG2b AT1S5 Purified Hu E, ICC/IF, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

Thymidylate synthase (TS) antibody

HeLa cells were stained with monoclonal anti-TYMS antibody (Green). Nucleus and Actin were stained by Phalloidin-TRITC (Red) or Hoechst 33342 (Blue). Mouse IgG2b AT1S5 Purified Hu E, ICC/IF, WB
50 µl / €230.00
  Acris Antibodies GmbH

Thymidylate synthase (TS) antibody

Thymidylate synthase (TS) Mouse IgG1 TS106 Purified Hu C, F, ICC/IF, IP, P, WB
0.2 mg / €410.00
  Acris Antibodies GmbH

Thymidylate synthase (TS) antibody

Thymidylate synthase (TS) Mouse IgG1 TS106 Purified Hu C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Thymidylate synthase (TS) antibody

Thymidylate synthase (TS) Mouse IgG1 TS106 Purified Hu C, F, ICC/IF, IP, P, WB
20 µg / €180.00
  Acris Antibodies GmbH

Thymidylate synthase (TS) antibody

Thymidylate synthase (TS) Mouse IgG1 SPM453 Purified Hu C, F, ICC/IF, IP, P, WB
0.2 mg / €410.00
  Acris Antibodies GmbH

Thymidylate synthase (TS) antibody

Thymidylate synthase (TS) Mouse IgG1 SPM453 Purified Hu C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Thymidylate synthase (TS) antibody

Thymidylate synthase (TS) Mouse IgG1 SPM453 Purified Hu C, F, ICC/IF, IP, P, WB
20 µg / €180.00
  Acris Antibodies GmbH

Thymidylate synthase (TS) antibody

  Rabbit polyclonal antibody to Thymidylate synthetase (thymidylate synthetase)  
Sample (30 ug of whole cell lysate). A: H1299. 10% SDS PAGE. TA308802 diluted at 1:1000. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Thymidylate synthase (TS) antibody

  Sheep polyclonal Thymidylate Synthase antibody  
Anti-TS is shown to detect thymidylate synthase present in a HeLa cell extract. Each lane is estimated to contain 4 ug of protein. Lanes 1, 2 and 3 represent 1:2,000, 1:5,000 and 1:10,000 fold dilutions of the antibody. Detection was made using HRP Rabbit-a-Sheep IgG (613-4302) diluted 1:1,000 and color development using TMB (TMBM-100) substrate for approximately 4'. Sheep Purified Hu E, WB
0.1 mg / €356.00
  OriGene Technologies, Inc.

Thymidylate synthase (TS) antibody

  Sheep polyclonal Thymidylate Synthase antibody  
Anti-TS is shown to detect thymidylate synthase present in a HeLa cell extract. Each lane is estimated to contain 4 ug of protein. Lanes 1, 2 and 3 represent 1:2,000, 1:5,000 and 1:10,000 fold dilutions of the antibody. Detection was made using HRP Rabbit-a-Sheep IgG (613-4302) diluted 1:1,000 and color development using TMB (TMBM-100) substrate for approximately 4'. Sheep Serum Hu, Ms, Rt C, E, IP, WB
2 ml / €1,070.00
  OriGene Technologies, Inc.

Thymidylate synthase (TS) antibody

  Rabbit polyclonal Thymidylate Synthase antibody  
Anti-TS is shown to detect thymidylate synthase present in a HeLa cell extract. Each lane is estimated to contain 4 ug of protein. Lanes 1, 2 and 3 represent 1:500, 1:1,000 and 1:2,000 fold dilutions of the antibody. Detection was made using HRP Goat-a-Rabbit IgG (611-1302) diluted 1:1,000 and color development using TMB (TMBM-100) substrate for approximately 4'. Rabbit Serum Hu, Mky, Ms, Rt C, E, ICC/IF, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

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