Thyroglobulin antibody

Principal name

Thyroglobulin antibody

Alternative names for Thyroglobulin antibody

Thyreoglobulin, TGN

SwissProt ID

O08710 (Mouse), P01266 (Human), P01267 (Bovin), P06882 (Rat)

Gene ID

7038 (TG), 21819 (Tg), 280706

Available reactivities

Hu (Human), Bov (Bovine), Rb (Rabbit), Can (Canine), Fe (Feline), Ms (Mouse), Por (Porcine), Rt (Rat), GP (Guinea Pig), Gt (Goat), Sh (Sheep), Chk (Chicken)

Available hosts

Mouse, Rabbit, Chicken

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), ELISA (capture) (E(capture)), Radioimmunoassay (R), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Immunoprecipitation (IP)

Background of Thyroglobulin antibody

Thyroglobulin is a 660 kDa dimeric preprotein with mutiple glycosylation sites is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformation maturation in the endoplasmic reticulation. Thyroglobulin dimerization as well as transport of thyroglobulin to the Golgi complex is calcium dependent. Thyroglobulin defects resulting from defective dimer formation and export to the Golgi is thought to cause some types of goiter. Antibody against thryoglobulin may be produced by individuals with other diseases arising from the gland such as Hashimoto's or Graves disease. Hence the presence of thyroglobulin autoantibodies can help to identify disease. Antibody to thyroglobulin has been shown to be useful for the identification of papillarly and follicular thyroid carcinoma; thyroglobulin antibody positive lesions are of thyroidal origin. Carcinomas of nonthyroidal origin do not express thyroglobulin and hence are thyroglobulin antibody negative. It is important to note though that not every type of thyroidal lesion is thyroglobulin antibody positive, a number of forms are negative. Hence a negative result does not necessarily rule out that a given lesion or metastasis originated from the thyroid gland.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Thyroglobulin antibody

Formalin-Fixed, Paraffin-Embedded Human thyroid stained with Thyroglobulin antibody Cat.-No. AM10143PU (Clone 2H11+6E1). Mouse IgG1 2H11 + 6E1 Purified Hu, Ms, Rt F, P, WB
0.2 mg / €410.00
  Acris Antibodies GmbH

Thyroglobulin antibody

Formalin-Fixed, Paraffin-Embedded Human thyroid stained with Thyroglobulin antibody Cat.-No. AM10143PU (Clone 2H11+6E1). Mouse IgG1 2H11 + 6E1 Purified Hu, Ms, Rt F, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Thyroglobulin antibody

Formalin-Fixed, Paraffin-Embedded Human thyroid stained with Thyroglobulin antibody Cat.-No. AM10143PU (Clone 2H11+6E1). Mouse IgG1 2H11 + 6E1 Purified Hu, Ms, Rt F, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Thyroglobulin antibody

Formalin-Fixed, Paraffin-Embedded Human thyroid stained with Thyroglobulin Antibody Cat.-No AM32841PU (Clone 6E1) at 1/200 dilution using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining. Mouse IgG1 6E1 Purified Hu, Ms, Rt F, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Thyroglobulin antibody

Formalin-Fixed, Paraffin-Embedded Human thyroid stained with Thyroglobulin Antibody Cat.-No AM32841PU (Clone 6E1) at 1/200 dilution using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining. Mouse IgG1 6E1 Purified Hu, Ms, Rt F, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Thyroglobulin antibody

Formalin-Fixed, Paraffin-Embedded Human thyroid stained with Thyroglobulin Antibody Cat.-No AM32841PU (Clone 6E1) at 1/200 dilution using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining. Mouse IgG1 6E1 Purified Hu, Ms, Rt F, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Thyroglobulin antibody

Formalin-Fixed, Paraffin Human thyroid stained with Thyroglobulin Antibody Cat.-No AM33242PU (Clone 2H11). Mouse IgG1 2H11 Purified Hu, Ms, Rt C, F, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Thyroglobulin antibody

Formalin-Fixed, Paraffin Human thyroid stained with Thyroglobulin Antibody Cat.-No AM33242PU (Clone 2H11). Mouse IgG1 2H11 Purified Hu, Ms, Rt C, F, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Thyroglobulin antibody

Formalin-Fixed, Paraffin Human thyroid stained with Thyroglobulin Antibody Cat.-No AM33242PU (Clone 2H11). Mouse IgG1 2H11 Purified Hu, Ms, Rt C, F, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Thyroglobulin antibody

Formalin-Fixed, Paraffin Human thyroid stained with Thyroglobulin Antibody Cat.-No AM33262PU (Clone SPM517). Mouse IgG1 SPM517 Purified Hu, Ms, Rt F, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Thyroglobulin antibody

Formalin-Fixed, Paraffin Human thyroid stained with Thyroglobulin Antibody Cat.-No AM33262PU (Clone SPM517). Mouse IgG1 SPM517 Purified Hu, Ms, Rt F, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Thyroglobulin antibody

Formalin-Fixed, Paraffin Human thyroid stained with Thyroglobulin Antibody Cat.-No AM33262PU (Clone SPM517). Mouse IgG1 SPM517 Purified Hu, Ms, Rt F, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Thyroglobulin antibody

WB using anti-Thyroglobulin antibody. Separation was achieved under reducing conditions using a pre-cast 5% Tris-HCl gel from Bio-Rad Laboratories. This antibody recognizes a single 330 kDa band corresponding to human thyroglobulin as confirmed by the position of molecular weight markers (not shown). A 1:400 dilution of Mab anti-Thyroglobulin was used for 2h followed by detection using a 1:5,000 dilution of IRDyeTM800 conjugated Goat-a-Mouse IgG [H&L]. Mouse 2H11 Purified Can, Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Thyroglobulin antibody

Immunohistochemistry staining of Paraffin Thyroid tissue by Thyroglobulin antibody (dilution: 1:100 - 1:500; visualization of staining: Cytoplasmic) Mouse IgG1 2H11+6E1 Purified Hu P
1 ml / €380.00
  OriGene Technologies, Inc.

Thyroglobulin antibody

Immunohistochemistry staining of Paraffin Thyroid tissue by Thyroglobulin antibody (dilution: 1:100 - 1:500; visualization of staining: Cytoplasmic) Mouse IgG1 MRQ-41 Purified Hu P
1 ml / €260.00
  OriGene Technologies, Inc.

Thyroglobulin antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-TG mouse monoclonal antibody. (TA801456; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) Mouse IgG2b OTI3E12 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Thyroglobulin antibody

Immunohistochemical staining of paraffin-embedded Human thyroid tissue within the normal limits using anti-TG mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA803991) Mouse IgG1 OTI1D6 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Thyroglobulin antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TG (RC216216, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TG. Mouse IgG1 OTI11F8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Thyroglobulin antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-TG mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA803993) Mouse IgG1 OTI1B2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Thyroglobulin antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-TG mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804165) Mouse IgG1 OTI8E8 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

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