Thyrotropin beta chain antibody

Principal name

Thyrotropin beta chain antibody

Alternative names for Thyrotropin beta chain antibody

Thyrotropin subunit beta, Thyroid-stimulating hormone subunit beta, TSH, TSHB, TSH beta

SwissProt ID

O57340 (Chick), P01222 (Human), P01223 (Bovin), P01224 (Pig), P04652 (Rat), P12656 (Mouse), P54828 (Canfa), Q28376 (Horse), Q52R90 (Felca)

Gene ID

7252 (TSHB), 25653 (Tshb), 281552, 403973

Available reactivities

Hu (Human), Rt (Rat), Rb (Rabbit), Ms (Mouse), Bov (Bovine), Can (Canine)

Available hosts

Mouse, Rabbit, Sheep, Goat

Available applications

Enzyme Immunoassay (E), ELISA (capture) (E(capture)), ELISA (detection) (E(detection)), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Radioimmunoassay (R), Paraffin Sections (P), Western blot / Immunoblot (WB), EPair for Elisa (EPair), Immunoprecipitation (IP), Flow Cytometry (F)

Background of Thyrotropin beta chain antibody

Thyroid stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones.
TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity. 
TSH has a alpha subunit that is identical to the one in other glycoprotein hormones such as LH, FSH and HCG.

General readings

This product has been used in:Jirkalova V et al. Immunoradiometric and luminescence immunoenzymometric assay of human thyrotropin from dried blood spots for screening of neonatal hypothyroidism. Eur J Clin Chem Clin Biochem 34:823-7 (1996). PubMed PMID: 8933106

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Thyrotropin beta chain antibody

Immunohistochemistry staining of Paraffin Pituitary tissue by TSH antibody (dilution: 1:100 - 1:500; visualization of staining: Cytoplasmic) Rabbit Purified Hu P
1 ml / €160.00
  OriGene Technologies, Inc.

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG2a TSH-116 Aff - Purified Hu E, R
0.1 mg / €190.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG1 057-11005 Purified Hu E
1 mg / €310.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG1 204-12410 Purified Hu E
1 mg / €310.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG1 204-12252 Purified Hu E
1 mg / €310.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG1 057-11006 Purified Hu E
1 mg / €310.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG1 057-11005 Purified Hu E
1 mg / €310.00
  Acris Antibodies GmbH

Thyrotropin beta chain (beta + intact) antibody

Thyrotropin beta chain Mouse IgG1 057-11001 Purified Hu E
1 mg / €310.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG1 154 Purified Hu E
1 mg / €380.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG1 155 Purified Hu E
1 mg / €380.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG2a BC1A3A5 (3A5) Purified Hu E
1 mg / €520.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG1 183 Purified Hu
1 mg / €430.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG1 TSH-2 HRP Hu E, E(detection)
0.2 ml / €420.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG1 TSH-2 Aff - Purified Hu E
0.5 mg / €380.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG1 TSH220 Purified Hu C, ICC/IF, P
1 ml / €360.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG1 TSH220 Purified Hu C, ICC/IF, P
0.5 ml / €270.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Mouse IgG1 n.a Aff - Purified Hu E
1 mg / €300.00
  Acris Antibodies GmbH

Thyrotropin beta chain (intact) antibody

Thyrotropin beta chain Mouse IgG1 B31 Purified Hu E, EPair, Labeling
1 mg / €340.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Rabbit Purified Rt C, WB
50 µl / €420.00
  Acris Antibodies GmbH

Thyrotropin beta chain antibody

Thyrotropin beta chain Rabbit Purified Hu C, WB
50 µl / €490.00
  Acris Antibodies GmbH

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