TIMD1 / HAVCR1 antibody

Principal name

TIMD1 / HAVCR1 antibody

Alternative names for TIMD1 / HAVCR1 antibody

TIMD-1, TIM1, TIM-1, T cell membrane protein 1, HAVCR-1, T cell immunoglobulin and mucin domain-containing protein 1, Hepatitis A virus cellular receptor 1

SwissProt ID

O54947 (Rat), Q5QNS5 (Mouse), Q96D42 (Human)

Gene ID

26762 (HAVCR1), 286934 (Havcr1), 171283

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rat, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Flow Cytometry (F)

Background of TIMD1 / HAVCR1 antibody

KIM1(KIDNEY INJURY MOLECULE 1),also known as HAVCR1, HAVCR or TIM1, is a protein that in humans is encoded by the KIM1 gene. The KIM1 gene is mapped to 5q33.3. Biochemical, mutational, and cell adhesion analyses confirm that Tim1 is capable of homophilic Tim-Tim interactions. The features identified in murine KIM1 is conserved in human KIM1. The KIM1 protein is indeed a receptor for the virus through the infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV. Using a monoclonal antibody to mouse Tim1, Tim1 is expressed after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions. Ectopic expression of KIM1 during mouse T-cell differentiation leads to production of the Th2-type cytokine Il4, but not the Th1-type cytokine Ifng. KIM1-expressing epithelial cells internalized apoptotic bodies, and Kim1 is directly responsible for phagocytosis in cultured primary rat tubule epithelial cells and in porcine and canine epithelial cell lines.

General readings

Meyers JH., et al. (2005) Nat. Immunol. 6(5):455-464.Santiago C., et al. (2007) Immunity 26(3):299-310.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TIMD1 / HAVCR1 (N-term) antibody

  Rabbit Polyclonal TIM-1 Antibody  
Western blot analysis of TIM-1 in human uterus tissue lysate with TIM-1 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TIMD1 / HAVCR1 (Center) antibody

  Rabbit Polyclonal TIM-1 Antibody  
Western blot analysis of TIM-1 in human uterus tissue lysate with TIM-1 antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TIMD1 / HAVCR1 antibody

  Anti-HAVCR1 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm, Cell membrane. Positive control: Human lung cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human lung cancer tissue using HAVCR1 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TIMD1 / HAVCR1 antibody

  Anti-HAVCR1 Rabbit Polyclonal Antibody  
Predicted band size: 39 kDa . Positive control: k562 cell and Hela cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lane1: K562 cell lysate Lane1: Hela cell lysate Lysate: 40 ug per lane Primary antibody: 1/700 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 90 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TIMD1 / HAVCR1 antibody

  Rabbit Polyclonal TIM-1/KIM-1/HAVCR Antibody  
Western Blot: TIM-1 Antibody [TA336354] - Analysis of TIM-1 in human brain lysate in the A) absence and B) presence of immunizing peptide, and C) mouse brain lysate using TIM-1 antibody at 2 ug/ml. Rabbit Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TIMD1 / HAVCR1 antibody

  Rabbit Polyclonal Anti-HAVCR1 Antibody  
WB Suggested Anti-HAVCR1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: Human Muscle Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

TIMD1 / HAVCR1 antibody

  Goat Polyclonal Anti-TIM-1 Antibody  
TA348960 (2 ug/ml) staining of Kidney (A), Testis (B) and Uterus (C) lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TIMD1 / HAVCR1 antibody

  Rat Monoclonal anti-Tim-1 Antibody  
Mouse Tim-1 transfected cells stained with purified anti-mouse CD365 (Tim-1, clone RMT1-4), followed by anti-rat IgG FITC Rat RMT1-4 Purified Ms F
0.5 mg / €379.00
  OriGene Technologies, Inc.

TIMD1 / HAVCR1 antibody

Western blot analysis of human uterine lysate probed with Rabbit anti Human TIM-1 (AP05601PU-N) at 1(A) and 2(B) µg/ml. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €320.00
  Acris Antibodies GmbH

TIMD1 / HAVCR1 antibody

Western blot analysis of human uterine lysate probed with Rabbit anti Human TIM-1 (AP05601PU-N) at 1(A) and 2(B) µg/ml. Rabbit IgG Purified Hu, Ms, Rt WB
50 µg / €280.00
  Acris Antibodies GmbH

TIMD1 / HAVCR1 (200-300) antibody

Testis: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TIMD1 / HAVCR1 antibody

Testis: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TIMD1 / HAVCR1 antibody

Formalin-Fixed, Paraffin-Embedded Human Uterus stained with TIMD1 / HAVCR1 antibody Cat.-No AP08825PU-N at 5 µg/ml followed by biotinylated Goat anti-Rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TIMD1 / HAVCR1 antibody

TIMD1 / HAVCR1 Rat IgG2 3F22 Purified Ms WB
0.1 mg / €440.00
  Acris Antibodies GmbH

TIMD1 / HAVCR1 (Extracell. Dom.) antibody

TIM-1 was detected in paraffin-embedded human kidney tubule sections. Tissue was stained using HRP-DAB (brown) and  counterstained with hematoxylin (blue). Rat IgG2b Purified Hu E, WB
0.5 mg / €410.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

HAVCR1 - human gene knockout kit via CRISPR

HAVCR1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

HAVCR1 - human gene knockout kit via CRISPR

HAVCR1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

HAVCR1 - human gene knockout kit via CRISPR

HAVCR1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

HAVCR1 - human gene knockout kit via CRISPR

HAVCR1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Havcr1 - mouse gene knockout kit via CRISPR

Havcr1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

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