TIMP3 antibody

Principal name

TIMP3 antibody

Alternative names for TIMP3 antibody

Protein MIG-5, TIMP-3, Metalloproteinase inhibitor 3, Tissue inhibitor of metalloproteinases 3

SwissProt ID

O73746 (Xenla), O97590 (Rabit), P26652 (Chick), P35625 (Human), P39876 (Mouse), P48032 (Rat), P79121 (Bovin), Q9TUL9 (Horse)

Gene ID

7078 (TIMP3), 373596 (timp3), 21859 (Timp3)

Available reactivities

Frog, Hu (Human), Rb (Rabbit), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TIMP3 antibody

The tissue inhibitors of metalloproteinases (TIMPs) are naturally occurring proteins that specifically inhibit matrix metalloproteinases and regulate extracellular matrix turnover and tissue remodeling by forming tightly bound inhibitory complexes with the MMPs. Thus, TIMPs maintain the balance between matrix destruction and formation. An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP proteins share several structural features including six loops held in place by six disulfide bonds arranged in three knotlike structures. The N terminal region is necessary for inhibitory activity. The N terminus of each TIMP contains a consensus sequence (VIRAK) and each TIMP is translated with a 29 amino acid leader sequence that is cleaved to produce the mature protein. The C terminal regions are divergent and enhance the inhibition selectivity and binding efficiency. Although the TIMP proteins share high homology, following secretion they are localized extracellularly either in soluble form (TIMP1, TIMP2, and TIMP4) or bound to extracellular matrix components (TIMP3).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TIMP3 (175-211) antibody

Formalin-Fixed, Paraffin-Embedded Human placenta stained with TIMP3 Antibody Cat.-No AP32837PU. Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rt F, ICC/IF, IP, P, WB
0.2 mg / €410.00
  Acris Antibodies GmbH

TIMP3 (175-211) antibody

Formalin-Fixed, Paraffin-Embedded Human placenta stained with TIMP3 Antibody Cat.-No AP32837PU. Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rt F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

TIMP3 (175-211) antibody

Formalin-Fixed, Paraffin-Embedded Human placenta stained with TIMP3 Antibody Cat.-No AP32837PU. Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rt F, ICC/IF, IP, P, WB
20 µg / €180.00
  Acris Antibodies GmbH

TIMP3 antibody

  Rabbit polyclonal anti-TIMP3 antibody  
Western blot analysis of extracts from HUVEC cells, using TIMP3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TIMP3 antibody

  Anti-TIMP3 Rabbit Polyclonal Antibody  
Predicted band size: 24 kDa . Positive control: Huvec cell lysate. Recommended dilution: 1/200-1000. (Gel: 12%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/250 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TIMP3 antibody

  Rabbit Polyclonal Anti-TIMP3 Antibody  
Western blot analysis on HuvEc cell lysate using TIMP3 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TIMP3 antibody

Western blot (WB) analysis of TIMP-3 antibody (Cat.-No. AP20507PU-N) in extracts from HUVEC cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

TIMP3 (C-term) antibody

Western blot analysis of rat kidney tissue lysis using TIMP3 antibody Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €340.00
  Acris Antibodies GmbH

TIMP3 (Center) antibody

Formalin-fixed and paraffin-embedded human breast carcinoma reacted with TIMP3 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TIMP3 antibody

Western blot analysis of extracts from HuvEc cells, using TIMP3 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

TIMP3 antibody

Western blot analysis of extracts from HuvEc cells, using TIMP3 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Timp3 - mouse gene knockout kit via CRISPR

Timp3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Timp3 - mouse gene knockout kit via CRISPR

Timp3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

ELISA Kits

Catalog No.    

Human TIMP-3 ELISA Kit

Human TIMP-3 ELISA Kit  
1 kit / €400.00
  OriGene Technologies, Inc.

OmniKine™ Human TIMP-3 ELISA Kit

OmniKine™ Human TIMP-3 ELISA Kit  
96 Tests / €440.00
  Assay Biotech

Lysates

Catalog No.    

TIMP3 overexpression lysate

TIMP3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TIMP3 (mGFP-tagged) - Human TIMP metallopeptidase inhibitor 3 (TIMP3), 200 uL, >10^7 TU/mL

Lenti ORF particles, TIMP3 (mGFP-tagged) - Human TIMP metallopeptidase inhibitor 3 (TIMP3), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, TIMP3 (Myc-DDK tagged) - Human TIMP metallopeptidase inhibitor 3 (TIMP3) , 200 uL, >10^7 TU/mL

Lenti ORF particles, TIMP3 (Myc-DDK tagged) - Human TIMP metallopeptidase inhibitor 3 (TIMP3) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Timp3 (GFP-tagged) - Mouse tissue inhibitor of metalloproteinase 3 (Timp3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Timp3 (GFP-tagged) - Mouse tissue inhibitor of metalloproteinase 3 (Timp3), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Timp3 (Myc-DDK-tagged) - Mouse tissue inhibitor of metalloproteinase 3 (Timp3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Timp3 (Myc-DDK-tagged) - Mouse tissue inhibitor of metalloproteinase 3 (Timp3), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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