Titin antibody

Principal name

Titin antibody

Alternative names for Titin antibody

TTN, Connectin, Rhabdomyosarcoma antigen MU-RMS-40.14

SwissProt ID

A2ASS6 (Mouse), Q8WZ42 (Human)

Gene ID

7273

Ncbi ID

9606, NP_003310

Available reactivities

Hu (Human), Rt (Rat), Av (Birds), Chk (Chicken), Fi (Fish), Mam (Mammalia), Ms (Mouse), Re (Reptiles)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoelectron Microscopy (EM)

Background of Titin antibody

Titin, also known as connectin, is a large protein involved in the temporal and spatial control of the assembly of the highly ordered sarcomeres (contractile units) of striated muscle. In addition to sarcomere assembly Titin also functions to maintain the structural integrity of the contracting myofibrils within the muscle and to organize the machinery for condensation of chromosomes in dividing cells. Titin is a giant protein composed of 27,000 amino acids and contains an autoregulated serine kinase catalytic domain as well as a calcium/calmodulin binding region that are involved in its activation. Activated Titin phosphorylates the muscle protein telethonin, a sarcomeric protein abundant in heart and skeletal muscle, implicating Titin activity in the reorganization of the cytoskeleton during myofibrillogenesis.

General readings

General / background references:Furst DO et al. The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: a map of ten nonrepetitive epitopes starting at the Z line extends close to the M line. J Cell Biol 106:1563-72 (1988). PubMed PMID: 2453516

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Titin antibody

Titin Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Titin antibody

Detection limit for recombinant GST tagged TTN is approximately 0.3ng/ml as a capture antibody. Mouse IgG 8G9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Titin antibody

Immunoperoxidase of monoclonal antibody to TTN on formalin-fixed paraffin-embedded human skeletal muscle. [antibody concentration 1 ug/ml] Mouse IgG1 2B3 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Titin antibody

Titin Mouse IgG 4D8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Titin antibody

Immunoperoxidase of monoclonal antibody to TTN on formalin-fixed paraffin-embedded human heart. [antibody concentration 3 ug/ml] Mouse IgG2a 7D3 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Titin antibody

Detection limit for recombinant GST tagged TTN is approximately 0.03ng/ml as a capture antibody. Mouse IgG 2F12 Purified Hu E, WB
50 µg / €370.00
  Abnova Taiwan Corp.

Titin antibody

Immunoperoxidase of monoclonal antibody to TTN on formalin-fixed paraffin-embedded human heart. [antibody concentration 3 ug/ml] Mouse IgG2a 6H5 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Titin antibody

Titin Mouse IgG2b T11 Purified Av, Chk, Fi, Hu, Mam, Ms, Re, Rt C, EM, ICC/IF, P, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Titin

Titin Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Titin

Titin Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Titin

Titin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Titin

Titin Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Titin

Titin Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

Titin

Titin Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Titin

Titin Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

15 Item(s)

per page
  • LinkedIn