TJP2 antibody

Principal name

TJP2 antibody

Alternative names for TJP2 antibody

Tight junction protein 2, Tight junction protein ZO-2, ZO2, X104, Zonula occludens protein 2, Zona occludens protein 2

SwissProt ID

Q95168 (Canfa), Q9UDY2 (Human), Q9Z0U1 (Mouse)

Gene ID

9414 (TJP2), 21873 (Tjp2)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit, Guinea Pig, Mouse

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of TJP2 antibody

Zona occludens 2 (ZO-2) is an ~160 kDa tight junction protein belonging to the membrane-associated guanlyate kinase (MAGUK) family. Members of this family are involved in epithelial and endothelial intercellular junctions. They each contain at least one PSD95/Dlg/ZO-1 (PDZ) domain, a Src homology 3 (SH3) domain, and an enzymatically inactive guanylate kinase domain. PDZ domains are 90-amino acid protein-protein binding domains that recognize at least a 3-residue peptide motif in the COOH termini of their binding partners. PDZ domain-containing proteins, like ZO-2, typically act as scaffolding proteins that organize membrane receptors and cytosolic proteins into multimeric signaling complexes often at the sites of cell-cell contact. The effectiveness and stability of the epithelial barrier depends on a complex of proteins composing different intercellular junctions, which include tight junctions, adherens junctions, and desmosomes.
ZO-2 can interact with zona occludens 1 (ZO-1). Furthermore, the PDZ2 domain of ZO-2 was shown to interact with connexin-43, the predominant connexin in epithelial and most other tissues which is involved in cell growth control and embryonic development.

General readings

Bel (2008) Hum. Genet. 123 (3), 267-272

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TJP2 (411-467) antibody

TJP2 Guinea Pig Ig Purified Hu, Ms C, ICC/IF, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

TJP2 antibody

TJP2 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

TJP2 antibody

TJP2 Mouse IgG2b 4D12 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TJP2 antibody

Human MCF-7; WB Suggested Anti-TJP2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: MCF7 cell lysate. TJP2 is supported by BioGPS gene expression data to be expressed in MCF7.; TJP2 antibody - middle region (ARP42941_P050) in Human MCF-7 cells using Western Blot Rabbit Aff - Purified Can, Hu WB
50 µg / €350.00
  AVIVA Systems Biology

TJP2 antibody

Human Jurkat; WB Suggested Anti-TJP2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Jurkat cell lysate; TJP2 antibody - C-terminal region (ARP42942_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

TJP2 antibody

TJP2 Rabbit IgG Aff - Purified Hu P, WB
0.1 mg / €290.00
  Boster Immunoleader

TJP2 antibody

TJP2 Rabbit IgG Aff - Purified Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

CRISPR

Catalog No. Species Donor Vector  

Tjp2 - mouse gene knockout kit via CRISPR

Tjp2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Tjp2 - mouse gene knockout kit via CRISPR

Tjp2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tjp2 - mouse gene knockout kit via CRISPR

Tjp2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tjp2 - mouse gene knockout kit via CRISPR

Tjp2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TJP2 (transcript variant 1)

TJP2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TJP2

TJP2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TJP2

TJP2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TJP2 293T Cell Transient Overexpression Lysate(Denatured)

TJP2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

TJP2 overexpression lysate

TJP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TJP2 (mGFP-tagged) - Human tight junction protein 2 (zona occludens 2) (TJP2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, TJP2 (mGFP-tagged) - Human tight junction protein 2 (zona occludens 2) (TJP2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, TJP2 (mGFP-tagged)-Human tight junction protein 2 (zona occludens 2) (TJP2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, TJP2 (mGFP-tagged)-Human tight junction protein 2 (zona occludens 2) (TJP2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €2,110.00
  OriGene Technologies, Inc.

Lenti ORF particles, TJP2 (mGFP-tagged)-Human tight junction protein 2 (zona occludens 2) (TJP2), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, TJP2 (mGFP-tagged)-Human tight junction protein 2 (zona occludens 2) (TJP2), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €2,390.00
  OriGene Technologies, Inc.

Lenti ORF particles, TJP2 (mGFP-tagged)-Human tight junction protein 2 (zona occludens 2) (TJP2), transcript variant 6, 200 uL, >10^7 TU/mL

Lenti ORF particles, TJP2 (mGFP-tagged)-Human tight junction protein 2 (zona occludens 2) (TJP2), transcript variant 6, 200 uL, >10^7 TU/mL  
200 µl / €2,030.00
  OriGene Technologies, Inc.

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