TMED10 / TMP21 antibody

Principal name

TMED10 / TMP21 antibody

Alternative names for TMED10 / TMP21 antibody

S31I125, Transmembrane emp24 domain-containing protein 10, 21 kDa transmembrane-trafficking protein, Transmembrane protein Tmp21

SwissProt ID

P49755 (Human), Q28735 (Rabit), Q5E971 (Bovin), Q63584 (Rat), Q9D1D4 (Mouse)

Gene ID

10972 (TMED10), 68581 (Tmed10), 84599

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Rb (Rabbit), Xen (Xenopus), Can (Canine), Ze (Zebrafish), African clawed frog, Prim (Primate), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C)

Background of TMED10 / TMP21 antibody

TMP21 (transmembrane protein Tmp21) is a type I transmembrane protein with large lumil domain belonging to p24 endoplasmic reticulum/Golgi cargo family and play key roles in protein transport, membrane structure organization and secretory pathway. TMP21 is ubiquitously expressed with highest protein levels observed in pancreas and intestines. In addition to its well established role in vesicle formation and cargo transport in ER/Golgi, TMP21 has been implicated in recruitment of small GTPase ADP-ribosylation factor 1 to Golgi apparatus and ADP-ribosylation factor 1-dependent assembly of actin in the Golgi. TMP21 forms a component of presenilin complex at the plasma membranes and modulates gamma -secretase cleavage. The cytoplasmic tails of p24 family interacts with coatomer (major component of coat protein complex I or COP-I), to facilitate transport between ER and Golgi. TMP21 cycles through the early secretory pathway between intermediate and cis-Golgi compartments, and is essential for proper organization of the Golgi apparatus. TMP21 also plays an essential and non-redundant role in earliest stages of mammalian development.

General readings

Chen F, Hasegawa H, et al. (2006). Nature. 440(7088):1208-12.Wang H, et al. (2002). J Biol Chem. 277(6):4541-50.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMED10 / TMP21 (C-term) antibody

  Rabbit Polyclonal TMP21 Antibody  
Western blot analysis of TMP21 in Raji cell lysate with TMP21 antibody at (A) 0.5 and (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TMED10 / TMP21 (Center) antibody

  Rabbit Polyclonal TMP21 Antibody  
Western blot analysis of TMP21 in mouse brain tissue lysate with TMP21 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TMED10 / TMP21 antibody

  Rabbit Polyclonal Tmp21/p23 Antibody  
Western Blot: TMP21 Antibody [TA336524] - Chicken embryo extract - Data supplied by Dr Yonghua Zhang of McGill University. Rabbit Purified Bov, Chk, Hu, Ms, Prim, Rt C, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TMED10 / TMP21 antibody

  Rabbit Polyclonal Tmp21/p23 Antibody  
Western Blot: TMP21 Antibody [TA336525] - Detection of TMP21 in human liver lysate using TA336525. Rabbit Purified Bov, Hu, Ms, Prim, Rb, Rt C, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TMED10 / TMP21 antibody

  Rabbit Polyclonal Anti-TMED10 Antibody - middle region  
WB Suggested Anti-TMED10 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Small Intestine Rabbit IgG Purified Can, GP, Hu, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMED10 / TMP21 antibody

Prostate: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TMED10 / TMP21 (C-term) antibody

Figure 2. Staining TMP21 in Breast tissue by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Rabbit Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

TMED10 - human gene knockout kit via CRISPR

TMED10 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TMED10 - human gene knockout kit via CRISPR

TMED10 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TMED10 - human gene knockout kit via CRISPR

TMED10 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TMED10 - human gene knockout kit via CRISPR

TMED10 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tmed10 - mouse gene knockout kit via CRISPR

Tmed10 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Tmed10 - mouse gene knockout kit via CRISPR

Tmed10 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tmed10 - mouse gene knockout kit via CRISPR

Tmed10 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tmed10 - mouse gene knockout kit via CRISPR

Tmed10 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TMED10 / TMP21 (32-185, His-tag)

TMED10 / TMP21 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH

TMED10 / TMP21 (32-185, His-tag)

TMED10 / TMP21 Human Purified > 85 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TMED10 (mGFP-tagged) - Human transmembrane emp24-like trafficking protein 10 (yeast) (TMED10), 200 uL, >10^7 TU/mL

Lenti ORF particles, TMED10 (mGFP-tagged) - Human transmembrane emp24-like trafficking protein 10 (yeast) (TMED10), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, TMED10 (Myc-DDK tagged) - Human transmembrane emp24-like trafficking protein 10 (yeast) (TMED10) , 200 uL, >10^7 TU/mL

Lenti ORF particles, TMED10 (Myc-DDK tagged) - Human transmembrane emp24-like trafficking protein 10 (yeast) (TMED10) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tmed10 (GFP-tagged ORF) - Rat transmembrane emp24-like trafficking protein 10 (yeast) (Tmed10), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tmed10 (GFP-tagged ORF) - Rat transmembrane emp24-like trafficking protein 10 (yeast) (Tmed10), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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