TMED10 / TMP21 antibody

Principal name

TMED10 / TMP21 antibody

Alternative names for TMED10 / TMP21 antibody

S31I125, Transmembrane emp24 domain-containing protein 10, 21 kDa transmembrane-trafficking protein, Transmembrane protein Tmp21

SwissProt ID

P49755 (Human), Q28735 (Rabit), Q5E971 (Bovin), Q63584 (Rat), Q9D1D4 (Mouse)

Gene ID

10972 (TMED10)

Available reactivities

Bov (Bovine), Chk (Chicken), Hu (Human), Mky (Monkey), Ms (Mouse), Rb (Rabbit), Rt (Rat), Xen (Xenopus), Can (Canine), Ze (Zebrafish), African clawed frog, Prim (Primate), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TMED10 / TMP21 antibody

TMP21 (transmembrane protein Tmp21) is a type I transmembrane protein with large lumil domain belonging to p24 endoplasmic reticulum/Golgi cargo family and play key roles in protein transport, membrane structure organization and secretory pathway. TMP21 is ubiquitously expressed with highest protein levels observed in pancreas and intestines. In addition to its well established role in vesicle formation and cargo transport in ER/Golgi, TMP21 has been implicated in recruitment of small GTPase ADP-ribosylation factor 1 to Golgi apparatus and ADP-ribosylation factor 1-dependent assembly of actin in the Golgi. TMP21 forms a component of presenilin complex at the plasma membranes and modulates gamma -secretase cleavage. The cytoplasmic tails of p24 family interacts with coatomer (major component of coat protein complex I or COP-I), to facilitate transport between ER and Golgi. TMP21 cycles through the early secretory pathway between intermediate and cis-Golgi compartments, and is essential for proper organization of the Golgi apparatus. TMP21 also plays an essential and non-redundant role in earliest stages of mammalian development.

General readings

Chen F, Hasegawa H, et al. (2006). Nature. 440(7088):1208-12.Wang H, et al. (2002). J Biol Chem. 277(6):4541-50.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMED10 / TMP21 (C-term) antibody

Western blot analysis of TMP21 in Raji cell lysate with TMP21 antibody at (A) 0.5 and (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TMED10 / TMP21 (Center) antibody

Western blot analysis of TMP21 in mouse brain tissue lysate with TMP21 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TMED10 / TMP21 antibody

Western Blot: TMP21 Antibody [TA336524] - Chicken embryo extract - Data supplied by Dr Yonghua Zhang of McGill University. Rabbit Purified Bov, Chk, Hu, Ms, Prim, Rt C, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TMED10 / TMP21 antibody

Western Blot: TMP21 Antibody [TA336525] - Detection of TMP21 in human liver lysate using TA336525. Rabbit Purified Bov, Hu, Ms, Prim, Rb, Rt C, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TMED10 / TMP21 antibody

WB Suggested Anti-TMED10 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Small Intestine Rabbit IgG Purified Can, GP, Hu, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMED10 / TMP21 antibody

Prostate: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TMED10 / TMP21 (C-term) antibody

Figure 2. Staining TMP21 in Breast tissue by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Rabbit Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TMED10 / TMP21 Control Peptide

TMED10 / TMP21
50 µg / €160.00
  Acris Antibodies GmbH

TMED10 / TMP21 Control Peptide

TMED10 / TMP21
50 µg / €160.00
  Acris Antibodies GmbH

TMED10 / TMP21 antibody

TMED10 / TMP21 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

TMED10 / TMP21 antibody

TMED10 / TMP21 Goat Hu, Ms, Rt E
0.1 mg / €390.00
  Abnova Taiwan Corp.

TMED10 / TMP21 antibody

Western blot analysis of TMED10 in human liver lysate with TMED10 polyclonal antibody ( Cat# PAB11997 ). Rabbit Bov, Chk, Hu, Ms, Rb, Rt WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

TMED10 / TMP21 antibody

Western blot analysis of TMED10 in human liver lysate with TMED10 polyclonal antibody ( Cat# PAB11998 ). Rabbit Bov, Hu, Ms, Rb, Rt, Xen C, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

TMED10 / TMP21 antibody

Immunohistochemistry of TMED10 in human brain tissue with TMED10 polyclonal antibody ( Cat # PAB13235 ) at 2.5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

TMED10 / TMP21 antibody

Immunohistochemistry of TMED10 in human brain tissue with TMED10 polyclonal antibody ( Cat # PAB13236 ) at 5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

TMED10 / TMP21 antibody

Human Small Intestine; WB Suggested Anti-TMED10 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Small Intestine; TMED10 antibody - middle region (ARP58728_P050) in Human Small Intestine cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rb, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

TMED10 / TMP21 antibody

TMED10 / TMP21 Rabbit Biotin Bov, Hu, Mky, Ms, Rb, Rt P, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

TMED10 / TMP21 antibody

TMED10 / TMP21 Rabbit DyLight488 Bov, Hu, Mky, Ms, Rb, Rt P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

TMED10 / TMP21 antibody

TMED10 / TMP21 Rabbit HRP Bov, Hu, Mky, Ms, Rb, Rt P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

TMED10 / TMP21 Control Peptide

TMED10 / TMP21
50 µg / €140.00
  Novus Biologicals Inc.

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