TMED2 / RNP24 antibody

Principal name

TMED2 / RNP24 antibody

Alternative names for TMED2 / RNP24 antibody

Transmembrane emp24 domain-containing protein 2

SwissProt ID

Q15363 (Human), Q63524 (Rat), Q9R0Q3 (Mouse)

Gene ID

10959 (TMED2), 56334 (Tmed2), 65165

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of TMED2 / RNP24 antibody

Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1. In COPI vesicle-mediated retrograde transport inhibits the GTPase-activating activity of ARFGAP1 towards ARF1 thus preventing immature uncoating and allowing cargo selection to take place. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2RL1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Facilitates CASR maturation and stabilization in the early secretory pathway and increases CASR plasma membrane targeting. Proposed to be involved in organization of intracellular membranes such as the maintenance of the Golgi apparatus. May also play a role in the biosynthesis of secreted cargo such as eventual processing.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMED2 / RNP24 antibody

  Rabbit Polyclonal antibody to TMED2 (transmembrane emp24 domain trafficking protein 2)  
Sample (30 ug of whole cell lysate). A: Raji. 12% SDS PAGE. TA308994 diluted at 1:1000. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TMED2 / RNP24 antibody

  Rabbit Polyclonal Anti-TMED2 Antibody  
WB Suggested Anti-TMED2 Antibody; Titration: 1.0 ug/ml; Positive Control: Placenta Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMED2 / RNP24 antibody

  Rabbit Polyclonal Anti-TMED2 Antibody  
Gel: 12%SDS-PAGE,Lysate: 40 ug,Lane 1-3: PC3 cells, A549 cells, Raji cells,Primary antibody: (TMED2 Antibody) at dilution 1/400 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 3 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

TMED2 - human gene knockout kit via CRISPR

TMED2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TMED2 - human gene knockout kit via CRISPR

TMED2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TMED2 - human gene knockout kit via CRISPR

TMED2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TMED2 - human gene knockout kit via CRISPR

TMED2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tmed2 - mouse gene knockout kit via CRISPR

Tmed2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Tmed2 - mouse gene knockout kit via CRISPR

Tmed2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tmed2 - mouse gene knockout kit via CRISPR

Tmed2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tmed2 - mouse gene knockout kit via CRISPR

Tmed2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tmed2 (GFP-tagged ORF) - Rat transmembrane emp24 domain trafficking protein 2 (Tmed2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tmed2 (GFP-tagged ORF) - Rat transmembrane emp24 domain trafficking protein 2 (Tmed2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tmed2 (Myc-DDK-tagged ORF) - Rat transmembrane emp24 domain trafficking protein 2 (Tmed2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tmed2 (Myc-DDK-tagged ORF) - Rat transmembrane emp24 domain trafficking protein 2 (Tmed2), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

13 Item(s)

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