TMEM123 / Porimin antibody

Principal name

TMEM123 / Porimin antibody

Alternative names for TMEM123 / Porimin antibody

Transmembrane protein 123, KCT3, KCT-3, PSEC0111, Pro-oncosis receptor inducing membrane injury, Keratinocytes-associated transmembrane protein 3

SwissProt ID

Q5HZB0 (Rat), Q8N131 (Human), Q91Z22 (Mouse)

Gene ID

114908 (TMEM123), 71929 (Tmem123), 363013

Available reactivities

Hu (Human), Chk (Chicken), Eq (Equine), Hst (Hamster), Mky (Monkey), Ms (Mouse), Prim (Primate), Rb (Rabbit), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of TMEM123 / Porimin antibody

TMEM123 is a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. TMEM123 is proposed to function as a cell surface receptor that mediates cell death.This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.

General readings

Zhang,Z. (2004) Protein Sci. 13 (10), 2819-2824

16 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMEM123 / Porimin antibody

  Rabbit Polyclonal Anti-TMEM123 Antibody  
WB Suggested Anti-TMEM123 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Placenta Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMEM123 / Porimin antibody

  Rabbit Polyclonal Anti-TMEM123 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (TMEM123 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TMEM123 / Porimin (173-188) antibody

Kidney: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Purified Elephant, Hu, Mky, Rb P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

TMEM123 - human gene knockout kit via CRISPR

TMEM123 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TMEM123 - human gene knockout kit via CRISPR

TMEM123 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TMEM123 - human gene knockout kit via CRISPR

TMEM123 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TMEM123 - human gene knockout kit via CRISPR

TMEM123 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tmem123 - mouse gene knockout kit via CRISPR

Tmem123 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Tmem123 - mouse gene knockout kit via CRISPR

Tmem123 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tmem123 - mouse gene knockout kit via CRISPR

Tmem123 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tmem123 - mouse gene knockout kit via CRISPR

Tmem123 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TMEM123 (mGFP-tagged) - Human transmembrane protein 123 (TMEM123), 200 uL, >10^7 TU/mL

Lenti ORF particles, TMEM123 (mGFP-tagged) - Human transmembrane protein 123 (TMEM123), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, TMEM123 (Myc-DDK tagged) - Human transmembrane protein 123 (TMEM123) , 200 uL, >10^7 TU/mL

Lenti ORF particles, TMEM123 (Myc-DDK tagged) - Human transmembrane protein 123 (TMEM123) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tmem123 (Myc-DDK-tagged) - Mouse transmembrane protein 123 (Tmem123), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tmem123 (Myc-DDK-tagged) - Mouse transmembrane protein 123 (Tmem123), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tmem123 (GFP-tagged ORF) - Rat transmembrane protein 123 (Tmem123), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tmem123 (GFP-tagged ORF) - Rat transmembrane protein 123 (Tmem123), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tmem123 (Myc-DDK-tagged ORF) - Rat transmembrane protein 123 (Tmem123), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tmem123 (Myc-DDK-tagged ORF) - Rat transmembrane protein 123 (Tmem123), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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