TMEM23 / SGMS1 antibody

Principal name

TMEM23 / SGMS1 antibody

Alternative names for TMEM23 / SGMS1 antibody

Transmembrane protein 23, SMS1, Sphingomyelin synthase 1, MOB, Medulla oblongata-derived protein, Phosphatidylcholine:ceramide cholinephosphotransferase 1

SwissProt ID

A0AAS4 (Pig), Q7T3T4 (Chick), Q7TSX5 (Rat), Q86VZ5 (Human), Q8VCQ6 (Mouse)

Gene ID

259230 (SGMS1), 208449 (Sgms1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Immunoprecipitation (IP), Paraffin Sections (P)

Background of TMEM23 / SGMS1 antibody

Bidirectiol lipid cholinephosphotransferase is capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Sgms1 directly and specifically recognizes the choline head group on the substrate. It also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Sgms1 does not function strictly as a SM synthase and suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. Sgms1 may protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

General readings

Ding,T., (2008) J. Lipid Res. 49 (2), 376-385

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMEM23 / SGMS1 antibody

WB Suggested Anti-SGMS1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Hela cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMEM23 / SGMS1 antibody

WB Suggested Anti-Sgms1 Antibody; Titration: 1.0 ug/ml; Positive Control: Mouse Muscle Rabbit IgG Purified Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMEM23 / SGMS1 antibody

TMEM23 / SGMS1 Rabbit Purified Hu, Ms E, WB
0.1 mg / €480.00
  Acris Antibodies GmbH

TMEM23 / SGMS1 antibody

TMEM23 / SGMS1 Rabbit Purified Hu E, WB
0.1 mg / €480.00
  Acris Antibodies GmbH

TMEM23 / SGMS1 control peptide

TMEM23 / SGMS1 Purified
50 µg / €210.00
  Acris Antibodies GmbH

TMEM23 / SGMS1 antibody

Human kidney section stained
with anti-SMS-1 antibody (AP05279PU-N) at 2 µg/ml. Anti-rabbit Ig H+L HRP conjugate (5 µg/ml) without antigen retrieval. Rabbit Aff - Purified Hu, Ms C, E, WB
10 Blots / €480.00
  Acris Antibodies GmbH

TMEM23 / SGMS1 antibody

TMEM23 / SGMS1 Rabbit Hu, Ms E, WB
0.1 mg / €560.00
  Abnova Taiwan Corp.

TMEM23 / SGMS1 antibody

TMEM23 / SGMS1 Rabbit Hu E, WB
0.1 mg / €560.00
  Abnova Taiwan Corp.

TMEM23 / SGMS1 antibody

Human HeLa; WB Suggested Anti-SGMS1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Hela cell lysate. SGMS1 is supported by BioGPS gene expression data to be expressed in HeLa.; SGMS1 antibody - middle region (ARP55475_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

TMEM23 / SGMS1 antibody

Western Blot: sphingomyelin synthase 1 Antibody [NBP1-60081] - This Anti-SGMS1 antibody was used in Western Blot of Hela tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Por, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

TMEM23 / SGMS1 antibody

Immunohistochemistry-Paraffin: Sphingomyelin synthase 1 Antibody [NBP1-92435] - Immunohistochemical staining of human oral mucosa shows strong cytoplasmic and membranous positivity in squamous epithelial cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TMEM23 / SGMS1

TMEM23 / SGMS1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TMEM23 / SGMS1

TMEM23 / SGMS1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

13 Item(s)

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