TMEM30A / CDC50A antibody

Principal name

TMEM30A / CDC50A antibody

Alternative names for TMEM30A / CDC50A antibody

Transmembrane protein 30A, Cell cycle control protein 50A, C6orf67

SwissProt ID

Q5F362 (Chick), Q6AY41 (Rat), Q8VEK0 (Mouse), Q9NV96 (Human)

Gene ID

55754 (TMEM30A)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C)

Background of TMEM30A / CDC50A antibody

Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth, and, reconstituted to liposomes, predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). The ATP8A1:TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Required for the formation of the ATP8A2, ATP8B1 and ATP8B2 P-type ATPAse intermediate phosphoenzymes. Involved in uptake of platelet-activating factor (PAF), synthetic drug alkylphospholipid edelfosine, and, probably in association with ATP8B1, of perifosine. Also mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2, ATP8B4, ATP10A, ATP10B, ATP10D, ATP11A, ATP11B and ATP11C from the ER to other membrane localizations.

General readings

Katoh,Y. (2004) Oncol. Rep. 12 (4), 939-943

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMEM30A / CDC50A antibody

WB Suggested Anti-TMEM30A Antibody Titration: 1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt, Ze P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMEM30A / CDC50A antibody

Human Kidney; Rabbit Anti-TMEM30A Antibody. Catalog Number: ARP47410. Paraffin Embedded Tissue: Human Kidney. Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; TMEM30A Antibody - middle region (ARP47410_P050) in Human Kidney cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze P, WB
50 µg / €350.00
  AVIVA Systems Biology

TMEM30A / CDC50A antibody

Western Blot: TMEM30A Antibody [NBP1-59474] - This Anti-TMEM30A antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 0.25ug/ml. Rabbit Aff - Purified Can, Hu, Ms, Rt, Ze P, WB
50 µg / €440.00
  Novus Biologicals Inc.

TMEM30A / CDC50A antibody

Immunohistochemistry-Paraffin: TMEM30A Antibody [NBP1-86739] Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TMEM30A / CDC50A (transcript variant 1)

TMEM30A / CDC50A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TMEM30A / CDC50A

TMEM30A / CDC50A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

TMEM30A / CDC50A

TMEM30A / CDC50A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TMEM30A overexpression lysate

TMEM30A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

8 Item(s)

per page
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