TMEM38B antibody

Principal name

TMEM38B antibody

Alternative names for TMEM38B antibody

Transmembrane protein 38B, TRICB, TRIC-B, C9orf87, Trimeric intracellular cation channel type B

SwissProt ID

Q0VC58 (Bovin), Q68FV1 (Rat), Q9DAV9 (Mouse), Q9NVV0 (Human)

Gene ID

55151 (TMEM38B), 362521 (Tmem38b)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TMEM38B antibody

Intracellular Ca2+ levels are important in proper cellular functions and have prominent roles in various cell sigling pathways and are crucial for muscle contractions. Indeed, an important step leading to muscle contraction is the massive release of Ca2+ ions from the endoplasmic /sarcoplasmic reticulum (ER/SR) to the cytosol. A battery of results suggest that specific K+ channels are important to counteract the Ca2+ outflow in order to neutralize the negative potential created by the movement of Ca2+ ions. It is believed that TRIC channels are responsible for neutralizing this negative potential. Trimeric intracellular cation-specific (TRIC) channels are critical for proper magement of intracellular stores. TRIC-A and TRIC-B both belong to this family and are both permeable to monovalent ions with a preference for K+ . Both channels are localized to the ER/SR membrane. Each TRIC subunit contains three transmembrane domains, a cytoplasmic C-terminus and a lumil N-terminus. Functiol entities are formed by homotrimerizarion. The activity of TRIC-A is regulated by voltage whereas that of TRIC-B can be regulated by different mechanisms. Knock out studies of these channels have shown that TRIC-A knock mice are viable while those of TRIC-B die at the neotal stage. TRIC-A is mostly expressed in excitable tissues like the brain and muscle while TRIC-B is ubiquitously expressed.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMEM38B antibody

Western blot analysis of TMEM38B in rat thymus tissue lysate with TMEM38B antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TMEM38B antibody

Western blot analysis of rat brain (lanes 1 and 4), mouse brain (lanes 2 and 5) and SH-SY5Y (lanes 3 and 6) lysates: 1-3. Anti-TRIC-B antibody, (1:200).4-6. Anti-TRIC-B antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
50 µl / €325.00
  OriGene Technologies, Inc.

TMEM38B antibody

WB Suggested Anti-TMEM38B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Hela cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMEM38B (C-term) antibody

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TMEM38B Control Peptide

TMEM38B
50 µg / €160.00
  Acris Antibodies GmbH

TMEM38B antibody

Human HeLa; WB Suggested Anti-TMEM38B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Hela cell lysate; TMEM38B antibody - C-terminal region (ARP47395_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

TMEM38B antibody

Western Blot: TMEM38B Antibody [NBP1-59976] - This Anti-TMEM38B antibody was used in Western Blot of Hela tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

TMEM38B antibody

Immunohistochemistry-Paraffin: TMEM38B Antibody [NBP1-77093] - Mouse thymus tissue with TMEM38B antibody at 5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

TMEM38B antibody

Immunohistochemistry-Paraffin: TMEM38B Antibody [NBP1-88803] - Immunohistochemical staining of human adrenal gland shows strong cytoplasmic positivity in cortical cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TMEM38B

TMEM38B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

TMEM38B

TMEM38B Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

TMEM38B

TMEM38B Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TMEM38B overexpression lysate

TMEM38B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

13 Item(s)

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