TMEM59L antibody

Principal name

TMEM59L antibody

Alternative names for TMEM59L antibody

Transmembrane protein 59-like, BSMAP, C19orf4, Brain-specific membrane-anchored protein

SwissProt ID

Q0VCT2 (Bovin), Q5HZE8 (Rat), Q7TNI2 (Mouse), Q9UK28 (Human)

Gene ID

25789 (TMEM59L)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of TMEM59L antibody

TMEM59L Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59L is a type I membrane glycoprotein that is expressed in the brain. A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.

General readings

Elson GC, de Coignac AB, Aubry JP, et al. BSMAP, a novel protein expressed specifically in the brain whose gene is localized on chromosome 19p12. Biochem. Biophys. Res. Commun. 1999; 264:55-62.

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMEM59L (C-term) antibody

Western blot analysis of TMEM59L in rat heart tissue lysate with TMEM59L antibody at 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TMEM59L antibody

WB Suggested Anti-TMEM59L Antibody Titration: 1.25 ug/ml; Positive Control: Transfected 293T Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TMEM59L (C-term) Control Peptide

50 µg / €160.00
  Acris Antibodies GmbH

TMEM59L antibody

TMEM59L Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

TMEM59L antibody

Transfected 293T; WB Suggested Anti-TMEM59L Antibody Titration: 1.25ug/ml. Positive Control: Transfected 293T; TMEM59L antibody - N-terminal region (ARP46855_T100) in Transfected 293T cells using Western Blot Rabbit Aff - Purified Hu WB
0.1 mg / €310.00
  AVIVA Systems Biology

5 Item(s)

per page
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