TMEM59L antibody

Principal name

TMEM59L antibody

Alternative names for TMEM59L antibody

Transmembrane protein 59-like, BSMAP, C19orf4, Brain-specific membrane-anchored protein

SwissProt ID

Q0VCT2 (Bovin), Q5HZE8 (Rat), Q7TNI2 (Mouse), Q9UK28 (Human)

Gene ID

25789 (TMEM59L), 67937 (Tmem59l)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of TMEM59L antibody

Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59L is a type I membrane glycoprotein that is expressed in the brain. A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.

General readings

Elson GC, de Coignac AB, Aubry JP, et al. BSMAP, a novel protein expressed specifically in the brain whose gene is localized on chromosome 19p12. Biochem. Biophys. Res. Commun. 1999; 264:55-62.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMEM59L (C-term) antibody

  Rabbit Polyclonal TMEM59L Antibody  
Western blot analysis of TMEM59L in rat heart tissue lysate with TMEM59L antibody at 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TMEM59L antibody

  Rabbit Polyclonal Anti-TMEM59L Antibody  
WB Suggested Anti-TMEM59L Antibody Titration: 1.25 ug/ml; Positive Control: Transfected 293T Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TMEM59L (mGFP-tagged) - Human transmembrane protein 59-like (TMEM59L), 200 uL, >10^7 TU/mL

Lenti ORF particles, TMEM59L (mGFP-tagged) - Human transmembrane protein 59-like (TMEM59L), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, TMEM59L (Myc-DDK tagged) - Human transmembrane protein 59-like (TMEM59L) , 200 uL, >10^7 TU/mL

Lenti ORF particles, TMEM59L (Myc-DDK tagged) - Human transmembrane protein 59-like (TMEM59L) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tmem59l (GFP-tagged) - Mouse transmembrane protein 59-like (Tmem59l), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tmem59l (GFP-tagged) - Mouse transmembrane protein 59-like (Tmem59l), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tmem59l (Myc-DDK-tagged) - Mouse transmembrane protein 59-like (Tmem59l), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tmem59l (Myc-DDK-tagged) - Mouse transmembrane protein 59-like (Tmem59l), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

6 Item(s)

per page
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