TMPO / LAP2 alpha antibody

Principal name

TMPO / LAP2 alpha antibody

Alternative names for TMPO / LAP2 alpha antibody

Thymopoietin isoform alpha, Thymopoietin-related peptide isoform alpha, Lamina-associated polypeptide 2 isoform alpha

SwissProt ID

P42166 (Human), Q61033 (Mouse)

Gene ID

7112 (TMPO)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), African clawed frog, Rb (Rabbit), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Enzyme Immunoassay (E), ChIP assay (ChIP), Immunoprecipitation (IP)

Background of TMPO / LAP2 alpha antibody

Lamins are type V intermediate filament proteins and are grouped into constitutively expressed B-type lamins and developmentally regulated A-type lamins. Lamin-binding proteins in the nuclear lamina and the nuclear interior include several protein families and/or types of proteins in higher eukaryotes such as the inner nuclear membrane proteins, lamin B receptor, emerin, and MANI, three isoforms of lamina-associated polypeptide 1 (LAP 1), and several isoforms of LAP 2. Up to six LAP 2 isoforms derive from a single gene by alternative splicing in mammals and various isoforms have been described in Xenopus. The best characterized LAP2 isoforms are the inner nuclear membrane protein LAP 2 beta and the nucleoplasmic protein LAP 2 alpha, which are identical in their N-terminal 187-amino acid constant region but differ in their C termini. While LAP 2 beta binds to B-type lamins at the nuclear periphery and was suggested to regulate nuclear lamina growth , LAP 2 alpha specifically interacts with A-type lamins within the nuclear interior as part of a detergent/salt-resistant nucleoskeletal structure.

General readings

Harris CA, Andryuk PJ, Cline SW, et al. Structure and mapping of the human thymopoietin (TMPO) gene and relationship of human TMPO beta to rat lamin-associated polypeptide 2. Genomics 1995; 28:198-205.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMPO / LAP2 alpha antibody

Western blot analysis of extracts of various cell lines, using TMPO antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

TMPO / LAP2 alpha (N-term) antibody

Western blot analysis of Thymopoietin in HeLa cell lysate with Thymopoietin antibody at 0.25 ug/mLl in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TMPO / LAP2 alpha antibody

WB Suggested Anti-TMPO Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: SH-SYSY cell lysate;TMPO is strongly supported by BioGPS gene expression data to be expressed in Human SHSY5Y cells Rabbit IgG Purified Bov, Can, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMPO / LAP2 alpha antibody

WB Suggested Anti-TMPO Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMPO / LAP2 alpha antibody

WB Suggested Anti-TMPO Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human Thymus Rabbit IgG Purified Bov, Can, Eq, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMPO / LAP2 alpha (N-term) antibody

TMPO Antibody (N-term) (AP54295PU-N) western blot analysis in MDA-MB453 cell line lysates (35 µg/lane). This demonstrates the TMPO antibody detected the TMPO protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TMPO / LAP2 alpha (N-term) Control Peptide

Western blot analysis  in HeLa cell lysate with TMPO / LAP2 alpha antibody Cat.-No. AP55579PU-N at 0.25 µug/ml in (A) the absence and (B) the presence of blocking peptide.
50 µg / €160.00
  Acris Antibodies GmbH

TMPO / LAP2 alpha antibody

Immunofluorescence showing HeLa cells stained with TMPO polyclonal antibody ( Cat # PAB12358 ). Rabbit Hu, Ms, Rt ICC/IF, WB
0.1 ml / €560.00
  Abnova Taiwan Corp.

TMPO / LAP2 alpha antibody

Human Heart; WB Suggested Anti-TMPO Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human heart; TMPO antibody - N-terminal region (ARP44799_P050) in Human Heart cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

TMPO / LAP2 alpha antibody

LAP2 alpha Antibody Rabbit Serum Hu, Ms, Rt ChIP, ICC/IF, IP, WB
0.1 ml / €400.00
  Immuquest

TMPO / LAP2 alpha antibody

LAP2 alpha antibody [3A3] Mouse IgG1 3A3 Purified Hu ICC/IF, IP, WB
0.1 ml / €400.00
  Immuquest

TMPO / LAP2 alpha antibody

Immunofluorescence: LAP2 Antibody [NB100-676] - Immunofluorescence showing HeLa cells stained with anti-LAP2 alpha (serum 245-11) Rabbit Serum Hu, Ms, Rt ICC/IF, WB
50 µl / €380.00
  Novus Biologicals Inc.

TMPO / LAP2 alpha antibody

Western Blot: LAP2 Antibody [NBP1-59489] - This Anti-TMPO antibody was used in Western Blot of Fetal Heart tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

TMPO / LAP2 alpha antibody

Immunohistochemistry-Paraffin: LAP2 Antibody [NBP1-87822] -  staining of human stomach shows strong nuclear membrane positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

TMPO 293T Cell Transient Overexpression Lysate(Denatured)

TMPO 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

TMPO overexpression lysate

TMPO overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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