TMPRSS3 antibody

Principal name

TMPRSS3 antibody

Alternative names for TMPRSS3 antibody

Transmembrane protease serine 3, ECHOS1, TADG12, TADG-12, Tumor-associated differentially-expressed gene 12 protein

SwissProt ID

P57727 (Human), Q8K1T0 (Mouse)

Gene ID

64699 (TMPRSS3), 140765

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C)

Background of TMPRSS3 antibody

Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. The TMPRSS3 (also known as ECHOS1) gene, which encodes a transmembrane serine protease, has been found to be responsible for two non-syndromic recessive deafness loci located on human chromosome 21q22.3, DFNB8 and DFNB10.TMPRSS3, a 437 amno acid membrane bound serine protease and a member of the S1 peptidase family. TMPRSS3 contains an amino-terminal signalanchor sequence and a glycosylated extracellular region containing the serine protease domain. Two novel missense mutations of TMPRSS3, W251C and P404L, alter the highly conserved amino acids of the serine protease domain. TMPRSS3 is expressed in many tissues, including fetal cochlea, a subset of pancreatic cancer and various other cancer tissues. TMPRSS3 is also overexpressed in cancer, suggesting that it may be important for processes in metastasis formation and tumor invasion.

General readings

Lee YJ, Park D, Kim SY, Park WJ.
Pathogenic mutations but not polymorphisms in congenital and childhood onset autosomal recessive deafness disrupt the proteolytic activity of TMPRSS3.
J Med Genet. 2003 Aug;40(8):629-31. No abstract available.
PMID: 12920079

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMPRSS3 antibody

TA303305 (0.1µg/ml) staining of A431 cell lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TMPRSS3 antibody

Western blot analysis of extracts from HUVEC cells, using TMPRSS3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TMPRSS3 (Center) antibody

Western blot analysis of TMPRSS3 Antibody (Center) (Cat. #TA324881) in Hela, 293 cell line lysates (35ug/lane). TMPRSS3 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

TMPRSS3 antibody

Host: Rabbit; Target Name: Tmprss3; Sample Tissue: Mouse Kidney lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMPRSS3 antibody

WB Suggested Anti-TMPRSS3 Antibody Titration: 5% Milk; Positive Control: Mouse Brain lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMPRSS3 antibody

WB Suggested Anti-TMPRSS3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: A549 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMPRSS3 antibody

Immunohistochemistry analyzes of TMPRSS3 antibody (Cat.-No AP20427PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

TMPRSS3 antibody

Immunofluorescence of COS cells 293T transfected with pHATMPRSS3. Rabbit Aff - Purified Hu C, E, WB
25 µg / €430.00
  Acris Antibodies GmbH

TMPRSS3 antibody

Immunofluorescence of COS cells transfectecd with pHATMPRSS3 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

TMPRSS3 antibody

TMPRSS3 Mouse IgG2a 2E1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TMPRSS3 antibody

TMPRSS3 polyclonal antibody ( Cat # PAB7409 ) ( 0.1 µg/ml ) staining of A-431 cell lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

TMPRSS3 antibody

Immunofluorescence analysis of HeLa cells, using TMPRSS3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

TMPRSS3 antibody

Immunofluorescence analysis of HeLa cells, using TMPRSS3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

TMPRSS3 antibody

TMPRSS3 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

TMPRSS3 antibody

Immunohistochemical analysis of ECHOS1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

TMPRSS3 antibody

Immunohistochemical analysis of ECHOS1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

TMPRSS3 antibody

Immunohistochemical analysis of ECHOS1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

TMPRSS3 antibody

NB100-77342 (0.1µg/ml) staining of A431 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

TMPRSS3 antibody

Immunohistochemistry: TMPRSS3 Antibody [NBP1-19582] -  TMPRSS3 Antibody [NBP1-19582] - paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

TMPRSS3 antibody

TMPRSS3 Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

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