TMPRSS6 antibody

Principal name

TMPRSS6 antibody

Alternative names for TMPRSS6 antibody

Transmembrane protease serine 6, Matriptase-2

SwissProt ID

Q8IU80 (Human), Q9DBI0 (Mouse)

Gene ID

164656 (TMPRSS6)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of TMPRSS6 antibody

Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Required to sense iron deficiency. Overexpression suppresses activation of the HAMP promoter.Involvement in disease:Defects in TMPRSS6 are the cause of iron-refractory iron deficiency anemia (IRIDA); also known as hypochromic microcytic anemia with defect in iron metabolism or hereditary iron-handling disorder or pseudo-iron-deficiency anemia. Key features include congenital hypochromic microcytic anemia, very low mean corpuscular erythrocyte volume, low transferrin saturation, abnormal iron absorption characterized by no hematologic improvement following treatment with oral iron, and abnormal iron utilization characterized by a sluggish, incomplete response to parenteral iron.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMPRSS6 antibody

WB Suggested Anti-TMPRSS6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

TMPRSS6 antibody

Western Blot analysis of TMPRSS6 expression in transfected 293T cell line (H00164656-T01) by TMPRSS6 MaxPab polyclonal antibody.

Lane 1: TMPRSS6 transfected lysate(50.71 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

TMPRSS6 antibody

Human Liver; Liver; TMPRSS6 antibody - N-terminal region (ARP53188_P050) in Human Liver cells using Immunohistochemistry Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

TMPRSS6 antibody

Western Blot: Matriptase 2 Antibody [NBP1-57098] - This Anti-TMPRSS6 antibody was used in Western Blot of Jurkat     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TMPRSS6 (C-term DDK tag)

TMPRSS6 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

TMPRSS6

TMPRSS6 Human
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TMPRSS6 293T Cell Transient Overexpression Lysate(Denatured)

TMPRSS6 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

TMPRSS6 overexpression lysate

TMPRSS6 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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