TNFRSF19 / TRADE antibody

Principal name

TNFRSF19 / TRADE antibody

Alternative names for TNFRSF19 / TRADE antibody

TAJ, TROY, Toxicity and JNK inducer, Tumor necrosis factor receptor superfamily member 19

SwissProt ID

Q9JLL3 (Mouse), Q9NS68 (Human)

Gene ID

55504 (TNFRSF19), 29820 (Tnfrsf19)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Frozen Sections (C)

Background of TNFRSF19 / TRADE antibody

Analysis of EST clones and use of a signal sequence trap screening of the murine brain have lead to identification of a new member of the tumor necrosis factor receptor superfamily designated as TAJ and TROY, respectively. TAJ/TROY is a membrane protein of 423 amino acids with characteristic cysteine-rich motifs in the extracellular domain and a tumor necrosis factor receptor-associated factor (TRAF) 2 binding sequence in the cytoplasmic domain. Human TROY has 78% identity at the amino acid level with mouse TROY. The extracellular domain of TROY has significant homology with that of EDAR (another newly identified receptor belonging to TNF receptor family) that specifies hair follicle fate. The cytoplasmic domain of TAJ is different than other TNF receptor family members. Although its cytoplasmic domain does not contain death domain, TAJ/TROY induced cell death is probably mediated through a caspase-independent pathway. TAJ-induced JNK activation was not blocked by dominant-negative inhibitors of TRAF2, TRAF5, or ASK1, which have been previously implicated in JNK activation via TNFR1 and CD40. However, coimmunoprecipitation assays revealed that TAJ is capable of binding a number of different TRAF family members, and it is possible that TAJ-induced JNKactivation is mediated by an as yet untested TRAF homolog, such as TRAF6. TROY mRNA is highly expressed in brain, prostate and embryo and moderately expressed in the heart, lung, liver.

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TNFRSF19 / TRADE antibody

  Rabbit Polyclonal TROY/TNFRSF19 Antibody  
Western Blot: TROY Antibody [TA336577] - Analysis of TROY using TA336577 in T98G, a human glioblastoma cell line lysate. A protein band of approximately 46 kD is detected. Rabbit Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TNFRSF19 / TRADE (29-44, 204-219, 409-421) antibody

Prostate: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TNFRSF19 / TRADE (Extracell. Dom.) antibody

TNFRSF19 / TRADE Goat IgG Aff - Purified Ms C, E, WB
0.1 mg / €450.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

Tnfrsf19 - mouse gene knockout kit via CRISPR

Tnfrsf19 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Tnfrsf19 - mouse gene knockout kit via CRISPR

Tnfrsf19 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tnfrsf19 - mouse gene knockout kit via CRISPR

Tnfrsf19 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tnfrsf19 - mouse gene knockout kit via CRISPR

Tnfrsf19 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

TNFRSF19 overexpression lysate

TNFRSF19 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

TNFRSF19 overexpression lysate

TNFRSF19 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TNFRSF19 (mGFP-tagged) - Human tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, TNFRSF19 (mGFP-tagged) - Human tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,020.00
  OriGene Technologies, Inc.

Lenti ORF particles, TNFRSF19 (mGFP-tagged) - Human tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, TNFRSF19 (mGFP-tagged) - Human tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, TNFRSF19 (Myc-DDK tagged) - Human tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, TNFRSF19 (Myc-DDK tagged) - Human tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €910.00
  OriGene Technologies, Inc.

Lenti ORF particles, TNFRSF19 (Myc-DDK tagged) - Human tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, TNFRSF19 (Myc-DDK tagged) - Human tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tnfrsf19 (GFP-tagged) - Mouse tumor necrosis factor receptor superfamily, member 19 (cDNA clone MGC:40996 IMAGE:5256883), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tnfrsf19 (GFP-tagged) - Mouse tumor necrosis factor receptor superfamily, member 19 (cDNA clone MGC:40996 IMAGE:5256883), 200 uL, >10^7 TU/mL  
200 µl / €790.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tnfrsf19 (GFP-tagged) - Mouse tumor necrosis factor receptor superfamily, member 19 (Tnfrsf19), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Tnfrsf19 (GFP-tagged) - Mouse tumor necrosis factor receptor superfamily, member 19 (Tnfrsf19), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €990.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tnfrsf19 (Myc-DDK-tagged) - Mouse tumor necrosis factor receptor superfamily, member 19 (cDNA clone MGC:40996 IMAGE:5256883), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tnfrsf19 (Myc-DDK-tagged) - Mouse tumor necrosis factor receptor superfamily, member 19 (cDNA clone MGC:40996 IMAGE:5256883), 200 uL, >10^7 TU/mL  
200 µl / €700.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tnfrsf19 (Myc-DDK-tagged) - Mouse tumor necrosis factor receptor superfamily, member 19 (Tnfrsf19), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Tnfrsf19 (Myc-DDK-tagged) - Mouse tumor necrosis factor receptor superfamily, member 19 (Tnfrsf19), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

17 Item(s)

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