TNFRSF21 / Death receptor 6 (DR6) antibody

Principal name

TNFRSF21 / Death receptor 6 (DR6) antibody

Alternative names for TNFRSF21 / Death receptor 6 (DR6) antibody

Tumor necrosis factor receptor superfamily member 21

SwissProt ID

O75509 (Human), Q9EPU5 (Mouse)

Gene ID

27242 (TNFRSF21), 94185 (Tnfrsf21)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Rat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Frozen Sections (C), Paraffin Sections (P)

Background of TNFRSF21 / Death receptor 6 (DR6) antibody

Apoptosis is induced by certain cytokines including TNF and Fas ligand (CD95L) of the TNF family through their death domain containing receptors, TNF-R1 and Fas (CD95). Several novel death receptors including DR3, TRAIL-R1, and TRAIL-R2 were identified.
A new death domain containing receptor in the TNF-R family was cloned and termed DR6 for death receptor-6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-?B and JNK [1]. DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified yet. T cells from DR6-deficient mice showed preference toward Th2 differentiation in vitro, suggesting that DR6, working through JNK functions to attenuate the Th2 response [2]. Other studies of DR6-targeted mutant mice demonstrated that DR6 functions as a regulatory receptor for mediating CD4(+) T cell activation and maintaining proper immune responses [3].

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TNFRSF21 / Death receptor 6 (DR6) antibody

Western blot analysis of DR6 in K562 (1,3) and Raji (2,4) whole cell lysate in the absence (1,2) or presence (3,4) of blocking peptide (Catalog no. 2157P) with DR6 antibody at 1:500 dilution. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TNFRSF21 / Death receptor 6 (DR6) antibody

Western blot analysis of DR6 expression in lysate from Jurkat cells (Lane 1, 2), 3T3 cells (Lane 3) and rat kidney tissue lysate (Lane 4). Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TNFRSF21 / Death receptor 6 (DR6) antibody

Predicted band size: 72 kDa . Positive control: Human fetal brain tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 30 ug Primary antibody: 1/420 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TNFRSF21 / Death receptor 6 (DR6) antibody

WB Suggested Anti-TNFRSF21 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 721_B cell lysate.TNFRSF21 is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

TNFRSF21 / Death receptor 6 (DR6) (42-335) antibody

Flow Cytometry: HEK 293T cells were mock transfected (thin line) or transfected with an expression plasmid coding for the extracellular domain of Human DR6 (thick line). Rat IgG2a Luke-1 Aff - Purified Hu F
0.1 mg / €510.00
  Acris Antibodies GmbH

TNFRSF21 / Death receptor 6 (DR6) Control Peptide

TNFRSF21 / Death receptor 6 (DR6)
50 µg / €160.00
  Acris Antibodies GmbH

TNFRSF21 / Death receptor 6 (DR6) (42-335) antibody

Detection of DR6 transiently transfected into HeLa cells (green) using anti-DR6 antibody (DR-6-04-EC). Cell nuclei visualized by DAPI (blue). Mouse IgG1 DR-6-04-EC FITC Hu F
0.1 mg / €330.00
  Acris Antibodies GmbH

TNFRSF21 / Death receptor 6 (DR6) antibody

Detection of DR6 transiently transfected into HeLa cells (green) using anti-DR6 antibody (DR-6-04-EC). Cell nuclei visualized by DAPI (blue). Mouse IgG1 DR-6-04-EC Purified Hu F, ICC/IF, IP
0.1 mg / €260.00
  Acris Antibodies GmbH

TNFRSF21 / Death receptor 6 (DR6) antibody

TNFRSF21 / Death receptor 6 (DR6) Mouse IgG1 DR-06-04-EC Purified Hu F, IP
0.2 mg / €340.00
  Acris Antibodies GmbH

TNFRSF21 / Death receptor 6 (DR6) antibody

Detection of DR6 transiently transfected into HeLa cells (green) using anti-DR6 antibody (Klon DR-6-04-EC). Cell nuclei visualized by DAPI (blue). Mouse IgG1 DR-6-04-EC PE F
0.1 mg / €390.00
  Acris Antibodies GmbH

TNFRSF21 / Death receptor 6 (DR6) (42-56) antibody

Western blot analysis of DR6 in K562 (1,3) and Raji (2,4) whole cell lysate in the
absence (1,2) or presence (3,4) of blocking peptide with SP1298. Rabbit Aff - Purified Hu WB
0.1 mg / €320.00
  Acris Antibodies GmbH

TNFRSF21 / Death receptor 6 (DR6) antibody

TNFRSF21 MaxPab polyclonal antibody. Western Blot analysis of TNFRSF21 expression in human colon. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

TNFRSF21 / Death receptor 6 (DR6) antibody

TNFRSF21 MaxPab polyclonal antibody. Western Blot analysis of TNFRSF21 expression in human colon. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

TNFRSF21 / Death receptor 6 (DR6) antibody

Western Blot analysis of TNFRSF21 expression in transfected 293T cell line (H00027242-T03) by TNFRSF21 MaxPab polyclonal antibody.

Lane 1: TNFRSF21 transfected lysate(71.80 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

TNFRSF21 / Death receptor 6 (DR6) antibody

Detection limit for recombinant GST tagged TNFRSF21 is approximately 3ng/ml as a capture antibody. Mouse IgG2a 1B2 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

TNFRSF21 / Death receptor 6 (DR6) antibody

TNFRSF21 / Death receptor 6 (DR6) Mouse IgG1 1B1 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

TNFRSF21 / Death receptor 6 (DR6) antibody

HEK 293T cells were mock transfected ( thin line ) or transfected with an expression plasmid coding for the extracellular domain of human TNFRSF21 ( thick line ). Cells ( 5 X 105 ) were incubated on ice for 30 min in 50 µL FACS buffer ( PBS, 5% FCS, 0.02% sodium azide ) containing 1 µg/mL of TNFRSF21 monoclonal antibody, clone Luke-1 ( Cat # MAB3436 ). Rat IgG2a Luke-1 Hu F
0.1 mg / €640.00
  Abnova Taiwan Corp.

TNFRSF21 / Death receptor 6 (DR6) antibody

Detection of TNFRSF21 transiently transfected into HeLa cells ( green ) using TNFRSF21 monoclonal antibody, clone DR-6-04-EC ( Cat # MAB3877 ). Cell nuclei visualized by DAPI ( blue ). Mouse IgG1 DR-6-04-EC Hu F, ICC/IF, IP
0.1 mg / €390.00
  Abnova Taiwan Corp.

TNFRSF21 / Death receptor 6 (DR6) antibody

TNFRSF21 / Death receptor 6 (DR6) Mouse IgG1 DR-6-04-EC Hu F, IP
0.1 mg / €470.00
  Abnova Taiwan Corp.

TNFRSF21 / Death receptor 6 (DR6) antibody

Western blot analysis of 30 µg of total cell lysate from Jurkat ( lane 1 ) , HeLa ( lane 2 ) , and Daudi ( lane 3 ) cells with TNFRSF21 polyclonal antibody ( Cat # PAB0156 ) at 2 µg/ml. Rabbit Hu WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

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