TNFRSF6B / DCR3 antibody

Principal name

TNFRSF6B / DCR3 antibody

Alternative names for TNFRSF6B / DCR3 antibody

Decoy receptor 3, Decoy receptor for Fas ligand

SwissProt ID

O95407 (Human)

Gene ID

8771 (TNFRSF6B), 6298771 (accA)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Neutralisation (NEUT)

Background of TNFRSF6B / DCR3 antibody

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand (FasL) of the TNF family through their death domain containing receptors, TNFR1 and Fas (also known as CD95 or Apo-1). Recently, Pitti et al., 1998 have identified a molecule that can bind to FasL and block its binding to Fas (1). This molecule called, decoy receptor 3 (DcR3), is generally amplified in a number of lung and colon carcinomas suggesting that certain tumors may escape FasL-dependent cell death by expressing a decoy receptor that blocks FasL (1,2). An identical molecule was isolated by Yu et al, 1999 that also binds to FasL and another cellular ligand, LIGHT (herpes virus entry mediator (HVEM)-L) (3,4). It has been shown that LIGHT induces apoptosis of various tumor cells that express both lymphotoxinb receptor and HVEM/TR2 receptors. DcR3/TR6 is constitutively expressed in lung tissue, tumor cells and in endothelial cells (1,3). Like other members of TNFR superfamily, DcR1, DcR2 and OPG, DcR3/TR6 may act as an inhibitor of sigling through TNF family members, FasL and LIGHT. However, unlike DcR1 and DcR2, which are membrane-associated proteins, DcR3 is directly secreted into the extracellular space.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TNFRSF6B / DCR3 antibody

Western blot analysis of DcR3 in human heart (H), brain (B), and kidney (K) tissue lysates with DcR3 antibody at 1:500 dilution. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TNFRSF6B / DCR3 antibody

Western blot analysis of extracts from HepG2 cells, using TNFRSF6B antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TNFRSF6B / DCR3 antibody

Western blot analysis on HepG2 cell lysate using TNFRSF6B Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TNFRSF6B / DCR3 antibody

Immunohistochemistry (IHC) analysis of DcR3 antibody (Cat.-No.: AP20562PU-N) in paraffin-embedded human colon carcinoma tissue. Rabbit Aff - Purified Hu ICC/IF, P
0.1 mg / €350.00
  Acris Antibodies GmbH

TNFRSF6B / DCR3 Control Peptide

TNFRSF6B / DCR3
50 µg / €160.00
  Acris Antibodies GmbH

TNFRSF6B / DCR3 (N-term) antibody

TNFRSF6B antibody (N-term) (AP54313PU-N) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TNFRSF6B antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TNFRSF6B / DCR3 antibody

TNFRSF6B / DCR3 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

TNFRSF6B / DCR3 antibody

Detection limit for recombinant GST tagged TNFRSF6B is approximately 3ng/ml as a capture antibody. Mouse IgG2b 1F1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TNFRSF6B / DCR3 antibody

Immunoperoxidase of monoclonal antibody to TNFRSF6B on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml] Mouse IgG2a 7G5 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TNFRSF6B / DCR3 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using TNFRSF6B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P
50 µg / €205.00
  Assay Biotech

TNFRSF6B / DCR3 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using TNFRSF6B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P
0.1 mg / €310.00
  Assay Biotech

TNFRSF6B / DCR3 antibody

Immunohistochemistry: DcR3 Antibody [NBP1-19717] -  DcR3 Antibody [NBP1-19717] - paraffin-embedded human colon carcinoma tissue. Rabbit Aff - Purified Hu ICC/IF, P
0.1 mg / €420.00
  Novus Biologicals Inc.

TNFRSF6B / DCR3 antibody

TNFRSF6B / DCR3 Rabbit Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TNFRSF6B / DCR3

TNFRSF6B / DCR3 Human Human HEK293T cells
2 µg / €590.00
  Abnova Taiwan Corp.

TNFRSF6B / DCR3

TNFRSF6B / DCR3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TNFRSF6B / DCR3

TNFRSF6B / DCR3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

TNFRSF6B (Human) Matched Antibody Pair

TNFRSF6B (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

TNFRSF6B (Human) Matched Antibody Pair

TNFRSF6B (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TNFRSF6B overexpression lysate

TNFRSF6B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

TNFRSF6B overexpression lysate

TNFRSF6B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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