TNFSF18 / AITRL antibody

Principal name

TNFSF18 / AITRL antibody

Alternative names for TNFSF18 / AITRL antibody

GITRL, TL6, AITRL, hGITRL, Tumor necrosis factor ligand superfamily member 18, Activation-inducible TNF-related ligand, Glucocorticoid-induced TNF-related ligand

SwissProt ID

Q7TS55 (Mouse), Q9UNG2 (Human)

Gene ID

8995 (TNFSF18), 240873 (Tnfsf18)

Available reactivities

Ms (Mouse), Hu (Human), Can (Canine), Eq (Equine)

Available hosts

Rat, Mouse, Rabbit

Available applications

Flow Cytometry (F), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), EPair for Elisa (EPair), Immunoprecipitation (IP), Paraffin Sections (P)

Background of TNFSF18 / AITRL antibody

The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation, differentiation, and survival through regulating the activation of the transcription factor NF-kappaB and various mitogen-activated protein kinases (reviewed in 1). The glucocorticoid-induced tumor necrosis factor receptor (GITR) is an emerging member of this family that is expressed on CD4+ CD25+ regulatory T cells and appears to have crucial immune regulation functions (2,3). Its ligand GITRL is expressed in endothelial and antigen-presenting cells (4) and can activate NF-kappaB, induce both pro- and anti-apoptotic effects, inhibit the suppressive activity of regulatory T cells, and co-stimulate responder T cells through GITR (5). Dominant negative forms of NIK and TRAF2 expressed in transfected 293 cells substantially inhibited NF-kappaB activation, suggesting that the GITRL-GITR pathway involves both NIK and TRAF2 (4).

General readings

Tuyaerts S., et al. (2007) J. Leukoc. Biol. 82:93-105Chattopadhyay K., et al. (2007) Proc. Natl. Acad. Sci. U.S.A. 104:19452-19457

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TNFSF18 / AITRL antibody

  Rabbit Polyclonal GITRL Antibody  
Western blot analysis of (A) 5 ng, (B) 25 ng, and (C) 50 ng of purified recombinant GITRL with ITRL antibody at 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TNFSF18 / AITRL antibody

  Anti-Human AITRL Rabbit Polyclonal Antibody  
This antibody stained A-431 cells. The primary antibody was incubated at 3.0 ug/ml overnight at 4C followed by a fluorescent labeled secondary antibody. Optimal concentrations and conditions may vary. Information courtesy of the Cell Profiling group, SciLifeLab Stockholm. Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TNFSF18 / AITRL antibody

  Rabbit Polyclonal Anti-TNFSF18 Antibody  
WB Suggested Anti-TNFSF18 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Placenta Rabbit IgG Purified Can, Eq, Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

TNFSF18 / AITRL antibody

Direct ELISA using Biotin conjugated TNFSF18 / AITRL Antibody Cat.-No AP01144BT Rabbit Biotin Hu E, WB
50 µg / €340.00
  Acris Antibodies GmbH

TNFSF18 / AITRL antibody

Direct ELISA using Biotin conjugated TNFSF18 / AITRL Antibody Cat.-No AP01144BT Rabbit Biotin Hu E, WB
25 µg / €230.00
  Acris Antibodies GmbH

TNFSF18 / AITRL antibody

TNFSF18 / AITRL Rabbit Aff - Purified Hu E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

TNFSF18 / AITRL antibody

TNFSF18 / AITRL Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Acris Antibodies GmbH

TNFSF18 / AITRL (Center) antibody

Western blot analysis of TNFSF18 (arrow) using rabbit polyclonal TNFSF18 Antibody (Center) (AP54315PU-N). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TNFSF18 gene. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TNFSF18 / AITRL antibody

TNFSF18 / AITRL Rat IgG1 YGL386 Purified Ms F
0.1 mg / €330.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

TNFSF18 - human gene knockout kit via CRISPR

TNFSF18 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TNFSF18 - human gene knockout kit via CRISPR

TNFSF18 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TNFSF18 - human gene knockout kit via CRISPR

TNFSF18 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TNFSF18 - human gene knockout kit via CRISPR

TNFSF18 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TNFSF18 / AITRL

  Recombinant protein of human tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18)  
TNFSF18 / AITRL Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TNFSF18 / AITRL

  Purified recombinant protein of Human tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18)  
TNFSF18 / AITRL Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

TNFSF18 / AITRL

  Purified recombinant protein of Human tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18).  
TNFSF18 / AITRL Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 20 µg / €199.00

Special Price: 20 µg / €139.00

  OriGene Technologies, Inc.

TNFSF18 / AITRL (72-199)

TNFSF18 / AITRL Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

TNFSF18 / AITRL (72-199)

TNFSF18 / AITRL Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

TNFSF18 / AITRL (81-199, T7 tag)

TNFSF18 / AITRL Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €730.00
  Acris Antibodies GmbH

TNFSF18 / AITRL (81-199, T7 tag)

TNFSF18 / AITRL Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €300.00
  Acris Antibodies GmbH

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