TNFSF18 / AITRL antibody

Principal name

TNFSF18 / AITRL antibody

Alternative names for TNFSF18 / AITRL antibody

GITRL, TL6, AITRL, hGITRL, Tumor necrosis factor ligand superfamily member 18, Activation-inducible TNF-related ligand, Glucocorticoid-induced TNF-related ligand

SwissProt ID

Q7TS55 (Mouse), Q9UNG2 (Human)

Gene ID

8995 (TNFSF18), 240873

Available reactivities

Ms (Mouse), Hu (Human), Can (Canine), Rt (Rat), Eq (Equine)

Available hosts

Rat, Mouse, Rabbit

Available applications

Flow Cytometry (F), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), EPair for Elisa (EPair), Immunoprecipitation (IP), Frozen Sections (C), Paraffin Sections (P), Neutralisation (NEUT)

Background of TNFSF18 / AITRL antibody

The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation, differentiation, and survival through regulating the activation of the transcription factor NF-kappaB and various mitogen-activated protein kinases (reviewed in 1). The glucocorticoid-induced tumor necrosis factor receptor (GITR) is an emerging member of this family that is expressed on CD4+ CD25+ regulatory T cells and appears to have crucial immune regulation functions (2,3). Its ligand GITRL is expressed in endothelial and antigen-presenting cells (4) and can activate NF-kappaB, induce both pro- and anti-apoptotic effects, inhibit the suppressive activity of regulatory T cells, and co-stimulate responder T cells through GITR (5). Dominant negative forms of NIK and TRAF2 expressed in transfected 293 cells substantially inhibited NF-kappaB activation, suggesting that the GITRL-GITR pathway involves both NIK and TRAF2 (4).

General readings

Tuyaerts S., et al. (2007) J. Leukoc. Biol. 82:93-105Chattopadhyay K., et al. (2007) Proc. Natl. Acad. Sci. U.S.A. 104:19452-19457

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TNFSF18 / AITRL antibody

Western blot analysis of (A) 5 ng, (B) 25 ng, and (C) 50 ng of purified recombinant GITRL with ITRL antibody at 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TNFSF18 / AITRL antibody

This antibody stained A-431 cells. The primary antibody was incubated at 3.0 ug/ml overnight at 4C followed by a fluorescent labeled secondary antibody. Optimal concentrations and conditions may vary. Information courtesy of the Cell Profiling group, SciLifeLab Stockholm. Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TNFSF18 / AITRL antibody

WB Suggested Anti-TNFSF18 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Placenta Rabbit IgG Purified Can, Eq, Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

TNFSF18 / AITRL antibody

Direct ELISA using Biotin conjugated TNFSF18 / AITRL Antibody Cat.-No AP01144BT Rabbit Biotin Hu E, WB
50 µg / €340.00
  Acris Antibodies GmbH

TNFSF18 / AITRL antibody

Direct ELISA using Biotin conjugated TNFSF18 / AITRL Antibody Cat.-No AP01144BT Rabbit Biotin Hu E, WB
25 µg / €230.00
  Acris Antibodies GmbH

TNFSF18 / AITRL antibody

TNFSF18 / AITRL Rabbit Aff - Purified Hu E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

TNFSF18 / AITRL antibody

TNFSF18 / AITRL Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Acris Antibodies GmbH

TNFSF18 / AITRL (Center) antibody

Western blot analysis of TNFSF18 (arrow) using rabbit polyclonal TNFSF18 Antibody (Center) (AP54315PU-N). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TNFSF18 gene. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TNFSF18 / AITRL antibody

TNFSF18 / AITRL Rat IgG1 YGL386 Purified Ms F
0.1 mg / €330.00
  Acris Antibodies GmbH

TNFSF18 / AITRL antibody

TNFSF18 / AITRL Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

TNFSF18 / AITRL antibody

Western Blot analysis of TNFSF18 expression in transfected 293T cell line (H00008995-T01) by TNFSF18 MaxPab polyclonal antibody.

Lane 1: TNFSF18 transfected lysate(19.47 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

TNFSF18 / AITRL antibody

TNFSF18 / AITRL Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

TNFSF18 / AITRL antibody

TNFSF18 MaxPab rabbit polyclonal antibody. Western Blot analysis of TNFSF18 expression in HeLa. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

TNFSF18 / AITRL antibody

Western Blot analysis of TNFSF18 expression in transfected 293T cell line (H00008995-T02) by TNFSF18 MaxPab polyclonal antibody.

Lane 1: TNFSF18 transfected lysate(20.30 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

TNFSF18 / AITRL antibody

Detection limit for recombinant GST tagged TNFSF18 is approximately 1ng/ml as a capture antibody. Mouse IgG2a 6F7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TNFSF18 / AITRL antibody

Immunocytochemistry of TNFSF18 in THP-1 cells with TNFSF18 polyclonal antibody ( Cat # PAB12952 ) at 10 µg/ml. Rabbit Hu, Ms ICC/IF, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

TNFSF18 / AITRL antibody

Human Placenta; WB Suggested Anti-TNFSF18 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Placenta; TNFSF18 antibody - middle region (ARP46568_P050) in Human Placenta cells using Western Blot Rabbit Aff - Purified Can, Hu WB
50 µg / €350.00
  AVIVA Systems Biology

TNFSF18 / AITRL antibody

Immunocytochemistry/Immunofluorescence: GITRL Antibody [NBP1-77240] - THP-1 cells with GITRL antibody at 10 ug/ml. Rabbit Aff - Purified Hu, Ms C, E, ICC/IF, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

TNFSF18 / AITRL antibody

Immunohistochemistry-Paraffin: GITRL Antibody [NBP1-90198] - Immunohistochemical staining of human duodenum shows cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TNFSF18 / AITRL

TNFSF18 / AITRL Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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