TNIK antibody

Principal name

TNIK antibody

Alternative names for TNIK antibody

KIAA0551, TRAF2 and NCK-interacting protein kinase

SwissProt ID

P83510 (Mouse), Q9UKE5 (Human)

Gene ID

23043 (TNIK), 665113 (Tnik)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Dot blot (Dot), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of TNIK antibody

TNIK is a MSN protein kinase that interacts with both TNF receptor-associated factor 2 (TRAF2) and the adapter protein NCK. The protein has been shown to activate the c-Jun N-terminal kinase pathway when overexpressed in Phoenix-A cells, and this activation is mediated solely by the C-terminal germinal center kinase homology region. TNIK has been shown to phosphorylate gelsolin, the principal intracellular and extracellular actin-severing protein, in vitro. This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton. At least eight splice isoforms have been reported.
Northern analysis indicates TNIK expression in human heart, skeletal muscle, and brain, with lower levels of expression in kidney, liver, lung, and pancreas. ESTs have been isolated from human tissue libraries, including normal amnion, gallbladder, skin, and testis and cancerous bone, germ cell, nerve, and placenta.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TNIK antibody

  TNIK Rabbit Polyclonal (Internal) Antibody  
Anti-TNIK antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

TNIK antibody

  TNIK Rabbit Polyclonal (Internal) Antibody  
Anti-TNIK antibody IHC of human skeletal muscle, myocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

TNIK antibody

  TNIK Rabbit Polyclonal (Internal) Antibody  
Anti-TNIK antibody IHC of human skeletal muscle, myocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Ms P
50 µg / €400.00
  OriGene Technologies, Inc.

TNIK antibody

  TNIK Rabbit Polyclonal (Internal) Antibody  
Anti-TNIK antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Ms P
50 µg / €400.00
  OriGene Technologies, Inc.

TNIK pSer764 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P
0.4 ml / €370.00
  Acris Antibodies GmbH

TNIK (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TNIK antibody

Dot blot analysis of Phospho-TNIK-pS764 Pab and TNIK-pS764 Pab (AP14873PU-N)on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antobodies working concentration was 0.5ug per ml. P-Pab: phosphorylated antibody; NP-Pab: non-phophorylated antibody; P-Pep: phospho-peptide; NP-Pep: non-phospho-peptide. Rabbit Ig Aff - Purified Hu
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

TNIK - human gene knockout kit via CRISPR

TNIK - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TNIK - human gene knockout kit via CRISPR

TNIK - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tnik - mouse gene knockout kit via CRISPR

Tnik - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Tnik - mouse gene knockout kit via CRISPR

Tnik - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tnik - mouse gene knockout kit via CRISPR

Tnik - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tnik - mouse gene knockout kit via CRISPR

Tnik - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

TNIK overexpression lysate

TNIK overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TNIK (mGFP-tagged) - Human TRAF2 and NCK interacting kinase (TNIK), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, TNIK (mGFP-tagged) - Human TRAF2 and NCK interacting kinase (TNIK), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, TNIK (mGFP-tagged)-Human TRAF2 and NCK interacting kinase (TNIK), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, TNIK (mGFP-tagged)-Human TRAF2 and NCK interacting kinase (TNIK), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €2,530.00
  OriGene Technologies, Inc.

Lenti ORF particles, TNIK (mGFP-tagged)-Human TRAF2 and NCK interacting kinase (TNIK), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, TNIK (mGFP-tagged)-Human TRAF2 and NCK interacting kinase (TNIK), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €2,530.00
  OriGene Technologies, Inc.

Lenti ORF particles, TNIK (mGFP-tagged)-Human TRAF2 and NCK interacting kinase (TNIK), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, TNIK (mGFP-tagged)-Human TRAF2 and NCK interacting kinase (TNIK), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €2,530.00
  OriGene Technologies, Inc.

Lenti ORF particles, TNIK (mGFP-tagged)-Human TRAF2 and NCK interacting kinase (TNIK), transcript variant 5, 200 uL, >10^7 TU/mL

Lenti ORF particles, TNIK (mGFP-tagged)-Human TRAF2 and NCK interacting kinase (TNIK), transcript variant 5, 200 uL, >10^7 TU/mL  
200 µl / €2,530.00
  OriGene Technologies, Inc.

Lenti ORF particles, TNIK (Myc-DDK tagged) - Human TRAF2 and NCK interacting kinase (TNIK), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, TNIK (Myc-DDK tagged) - Human TRAF2 and NCK interacting kinase (TNIK), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

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