TNIP1 antibody

Principal name

TNIP1 antibody

Alternative names for TNIP1 antibody

TNFAIP3-interacting protein 1, KIAA0113, NAF1, Nip40-1, VAN, Nef-associated factor 1, HIV-1 Nef-interacting protein, Virion-associated nuclear shuttling protein

SwissProt ID

Q15025 (Human), Q9WUU8 (Mouse)

Gene ID

10318 (TNIP1)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P)

Background of TNIP1 antibody

This 5C4 monoclonal antibody reacts with human Nef-associated factor-1 (Naf-1). This protein is also designated as A20-binding inhibitor of NFkB activation (ABIN-1) and TNFAIP3-interacting protein 1 (TNIP1). Naf-1 is predicted to consist of four leucine zippers and four coiled-coil domains. This protein exists as two isoforms, Naf1alpha and Naf1beta, which are 72-kDa and 68-kDa, respectively, and is expressed in a variety of tissues, with greatest expression in peripheral blood lymphocytes, spleen, and skeletal muscle. Naf1 has also been detected in the Jurkat, Molt-4, and HL60 cell lines. Naf-1 has been shown to play several biological roles. Naf-1 was originally identified associated with the Nef protein of HIV, and was found to enhance CD4 cell surface expression. Naf-1 has also been demonstrated to inhibit TNF-alpha- and IL-1-mediated NFkB-dependent gene expression by competing with IKK-gamma. Finally, this adaptor protein has been found to associate constitutively with P-selectin glycoprotein ligand 1 (PSGL-1) in human leukocytes. Upon P-selectin binding to PSGL-1, Naf1 is phosphorylated at Tyr552 by Src family kinases, leading to PI3K recruitment and integrin activation. This antibody recognizes both the unphosphorylated and phosphorylated forms of Naf1alpha and Naf1beta.

General readings

He CF., et al. (2010) Lupus 19(10):1181-6.
Gateva V., et al. (2009) Nat Genet.41(11):1228-33.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TNIP1 (C-term) antibody

TNIP1 antibody (C-term) (AP54318PU-N) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TNIP1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TNIP1 antibody

Immunofluorescence of purified MaxPab antibody to TNIP1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

TNIP1 (C-term) antibody

Human HeLa; WB Suggested Anti-TNIP1 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Hela Whole Cell. TNIP1 is supported by BioGPS gene expression data to be expressed in HeLa.; TNIP1 antibody - C-terminal region (ARP61714_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

TNIP1 (N-term) antibody

Human U937; WB Suggested Anti-TNIP1 Antibody. . Titration: 1.0 ug/ml. . Positive Control: U937 Whole Cell; TNIP1 antibody - N-terminal region (ARP61715_P050) in Human U937 cells using Western Blot Rabbit Aff - Purified Hu
50 µg / €350.00
  AVIVA Systems Biology

TNIP1 antibody

TNIP1 Mouse IgG1 5C4 Aff - Purified Hu IP, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

TNIP1 antibody

TNIP1 Mouse IgG1 5C4 Aff - Purified Hu IP, P, WB
25 µg / €320.00
  Novus Biologicals Inc.

TNIP1 antibody

TNIP1 Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

TNIP1 antibody

TNIP1 Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

TNIP1 antibody

Immunohistochemistry-Paraffin: TNIP1 Antibody [NBP1-89306] - Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TNIP1

TNIP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TNIP1 (94-530, His-tag)

TNIP1 Human Purified > 75 % E. coli
50 µg / €750.00
  Acris Antibodies GmbH

TNIP1 (94-530, His-tag)

TNIP1 Human Purified > 75 % E. coli
10 µg / €300.00
  Acris Antibodies GmbH

TNIP1

TNIP1 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

TNIP1

TNIP1 Human
10 µg / €380.00
  Abnova Taiwan Corp.

TNIP1

TNIP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TNIP1

TNIP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

TNIP1

TNIP1 Human Purified
10 µg / €380.00
  Novus Biologicals Inc.

TNIP1

TNIP1 Human Purified
50 µg / €870.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

TNIP1 293T Cell Transient Overexpression Lysate(Denatured)

TNIP1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

TNIP1 overexpression lysate

TNIP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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