TNIP3 antibody

Principal name

TNIP3 antibody

Alternative names for TNIP3 antibody

ABIN3, ABIN-3, LIND, TNFAIP3-interacting protein 3, Listeria-induced gene protein, A20-binding inhibitor of NF-kappa-B activation 3

SwissProt ID

Q96KP6 (Human)

Gene ID

79931 (TNIP3)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C)

Background of TNIP3 antibody

The nuclear factor NF-kappaB plays key roles in development and immunity. ABIN3 (A20-binding inhibitor of NF-kappaB activation 3), also known as TNFAIP3-interacting protein 3 (TNIP3), is a novel negative feedback regulator of LPS-induced NF-kappaB activation. ABIN3 is a 39 kDa protein that negatively regulates NF-kappaB activation in response to TNF and LPS. ABIN3 is highly expressed in brain, thymus, lymph node, lung and fetal liver, with low expression in kidney, bone marrow. Through its interaction with A20, ABIN3 interferes with TRAF2-mediated transactivation signals and NF-kappaB inhibition is mediated by the ABIN-homology domain 2. ABIN3 has been found to be induced by Listeria infection and can be slightly downregulated by dexamethasone. Enhanced expression of ABIN3 in monocytes is associated with sepsis. Thus, ABIN3 is an IL-10-induced gene product capable of attenuating NF-kappaB in human macrophages yet is inoperative in mice and represents a basis for species-specific differences in IL-10 actions. At least four isoforms of ABIN3 are known to exist.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TNIP3 antibody

Western blot analysis of ABIN3 in human spleen tissue lysate with ABIN3 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TNIP3 antibody

WB Suggested Anti-TNIP3 Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Lung Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

TNIP3 (C-term) antibody

Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TNIP3 Control Peptide

TNIP3
50 µg / €160.00
  Acris Antibodies GmbH

TNIP3 antibody

TNIP3 Rabbit Aff - Purified Hu, Ms E, P, WB
50 µg / €480.00
  Novus Biologicals Inc.

TNIP3 antibody

Immunohistochemistry-Paraffin: TNIP3 Antibody [NBP1-77365] - Mouse spleen tissue with ABIN3 antibody at 5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

TNIP3 antibody

Immunohistochemistry-Paraffin: TNIP3 Antibody [NBP1-89305] Immunohistochemical staining of human colon shows strong cytoplasmic and membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TNIP3 (transcript variant 2)

TNIP3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

TNIP3 overexpression lysate

TNIP3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

TNIP3 overexpression lysate

TNIP3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

10 Item(s)

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