TNIP3 antibody

Principal name

TNIP3 antibody

Alternative names for TNIP3 antibody

ABIN3, ABIN-3, LIND, TNFAIP3-interacting protein 3, Listeria-induced gene protein, A20-binding inhibitor of NF-kappa-B activation 3

SwissProt ID

Q96KP6 (Human)

Gene ID

79931 (TNIP3)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of TNIP3 antibody

The nuclear factor NF-kB plays key roles in development and immunity. ABIN3 (A20-binding inhibitor of NF-kB activation 3), also known as TNFAIP3-interacting protein 3 (TNIP3), is a novel negative feedback regulator of LPS-induced NF-kB activation. ABIN3 is a 39 kDa protein that negatively regulates NF-kB activation in response to TNF and LPS. ABIN3 is highly expressed in brain, thymus, lymph node, lung and fetal liver, with low expression in kidney, bone marrow. Through its interaction with A20, ABIN3 interferes with TRAF2-mediated transactivation signals and NF-kB inhibition is mediated by the ABIN-homology domain 2. ABIN3 has been found to be induced by Listeria infection and can be slightly downregulated by dexamethasone. Enhanced expression of ABIN3 in monocytes is associated with sepsis. Thus, ABIN3 is an IL-10-induced gene product capable of attenuating NF-kB in human macrophages yet is inoperative in mice and represents a basis for species-specific differences in IL-10 actions. At least four isoforms of ABIN3 are known to exist.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TNIP3 antibody

  Rabbit Polyclonal ABIN3 Antibody  
Western blot analysis of ABIN3 in human spleen tissue lysate with ABIN3 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TNIP3 antibody

  Rabbit Polyclonal Anti-TNIP3 Antibody  
WB Suggested Anti-TNIP3 Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Lung Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

TNIP3 antibody

  Rabbit Polyclonal Anti-TNIP3 Antibody  
TNIP3 Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TNIP3 (C-term) antibody

Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

TNIP3 - human gene knockout kit via CRISPR

TNIP3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TNIP3 - human gene knockout kit via CRISPR

TNIP3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TNIP3 - human gene knockout kit via CRISPR

TNIP3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TNIP3 - human gene knockout kit via CRISPR

TNIP3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TNIP3 (transcript variant 2)

  Purified recombinant protein of Homo sapiens TNFAIP3 interacting protein 3 (TNIP3), transcript variant 2  
TNIP3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

TNIP3 overexpression lysate

TNIP3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

TNIP3 overexpression lysate

TNIP3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TNIP3 (mGFP-tagged) - Human TNFAIP3 interacting protein 3 (TNIP3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, TNIP3 (mGFP-tagged) - Human TNFAIP3 interacting protein 3 (TNIP3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, TNIP3 (mGFP-tagged) - Human TNFAIP3 interacting protein 3 (TNIP3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, TNIP3 (mGFP-tagged) - Human TNFAIP3 interacting protein 3 (TNIP3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, TNIP3 (Myc-DDK tagged) - Human TNFAIP3 interacting protein 3 (TNIP3), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, TNIP3 (Myc-DDK tagged) - Human TNFAIP3 interacting protein 3 (TNIP3), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Lenti ORF particles, TNIP3 (Myc-DDK tagged) - Human TNFAIP3 interacting protein 3 (TNIP3), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, TNIP3 (Myc-DDK tagged) - Human TNFAIP3 interacting protein 3 (TNIP3), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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