TNNI3K antibody

Principal name

TNNI3K antibody

Alternative names for TNNI3K antibody

CARK, Serine/threonine-protein kinase TNNI3K, TNNI3-interacting kinase, Cardiac ankyrin repeat kinase

SwissProt ID

Q59H18 (Human), Q59H18-1, Q5GIG6 (Mouse), Q7TQP6 (Rat)

Gene ID

51086 (TNNI3K), 100526835 (FPGT-TNNI3K)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Rt (Rat), Can (Canine), Chk (Chicken), Mky (Monkey), Rb (Rabbit), Xen (Xenopus), Ze (Zebrafish)

Available hosts

Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of TNNI3K antibody

TNNI3K, also known as CARK, is a 936 amino acid serine/threonine-protein kinase that is highly expressed in heart. Overexpression of TNNI3K leads to improved cardiac function by enhancing beating frequency and increasing contractile force and epinephrine response. TNNI3K suppresses phosphorylation of cardiac troponin I and p38/JNK-mediated apoptosis, therefore protecting the myocardium from ischemic injury. Administration of TNNI3K to mice with myocardial infarction improves cardiac performance and attentuates ventricular remodeling, suggesting that TNNI3K could be a promising target in the treatment of cardiac diseases. There are four isoforms of TNNI3K that are produced as a result of alternative splicing events.

General readings

Feng,Y., (2007) Biochemistry Mosc. 72 (11), 1199-1204

19 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TNNI3K antibody

Sample (30 ug of whole cell lysate). A: HeLaS3. 7.5% SDS PAGE. TA308400 diluted at 1:5000 Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TNNI3K antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using TNNI3K antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TNNI3K antibody

TNNI3K MaxPab rabbit polyclonal antibody. Western Blot analysis of TNNI3K expression in mouse testis. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

TNNI3K antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TNNI3K Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
50 µg / €205.00
  Assay Biotech

TNNI3K antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TNNI3K Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €310.00
  Assay Biotech

TNNI3K (N-term) antibody

Human Jurkat; WB Suggested Anti-TNNI3K Antibody Titration: 0.2-1 ug/ml. Positive Control: Jurkat cell lysate; TNNI3K antibody - N-terminal region (ARP48044_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

TNNI3K antibody

Human HepG2; WB Suggested Anti-TNNI3K Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: HepG2 cell lysate; TNNI3K antibody - middle region (ARP48045_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

TNNI3K antibody

Immunohistochemical analysis of CARK staining in human heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Ms, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

TNNI3K antibody

Immunohistochemical analysis of CARK staining in human heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Ms, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

TNNI3K antibody

Immunohistochemical analysis of CARK staining in human heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Ms, Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

TNNI3K antibody

Immunofluorescence: TNNI3K Antibody [NBP1-32837] - Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TNNI3K antibody at 1:200 dilution. Rabbit IgG Hu ICC/IF, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

TNNI3K antibody

Western Blot: TNNI3K Antibody [NBP1-57841] - This Anti-TNNI3K antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TNNI3K (transcript variant 2)

TNNI3K Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TNNI3K

TNNI3K Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

TNNI3K

TNNI3K Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

TNNI3K

TNNI3K Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TNNI3K

TNNI3K Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

TNNI3K

TNNI3K Human
5 µg / €610.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

TNNI3K overexpression lysate

TNNI3K overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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