TOMM70A antibody

Principal name

TOMM70A antibody

Alternative names for TOMM70A antibody

TOM70, KIAA0719, Mitochondrial import receptor subunit TOM70, Mitochondrial precursor proteins import receptor, Translocase of outer membrane 70 kDa subunit

SwissProt ID

O94826 (Human), Q75Q39 (Rat), Q9CZW5 (Mouse)

Gene ID

9868 (TOMM70A), 304017 (Tomm70a)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of TOMM70A antibody

Most of mitochondrial proteins are synthesized by cytosolic ribosomes followed by import into mitochondria post-translatiolly with the help of cytosolic chaperones as well as mitochondrial translocators (import components). Translocase of the outer membrane (TOM) complex (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70) is the proteiceous machinery that contains surface receptors for pre-protein recognition and serve as main entry gateway into mitochondria. Mitochondrial targeting requires different cytosolic factors, in particular the molecular chaperones (Hsc70/Hsp70 and Hsp90) whose activity occur in coordited cycles of ATP hydrolysis/substrate binding and are regulated by a number of co-chaperone proteins including TOM70, a member of TPR (tetratricopeptide repeat) co-chaperone family. TOM70 contains a conserved TPR clamp domain for interaction with Hsc70 and Hsp90, and such interaction is essential for import process initiation. TOMM70 is a single-pass membrane protein localized in mitochondrion outer membrane and is ubiquitously expressed in various tissues where it acts as a receptor that accelerates the import of all mitochondrial precursor proteins. In addition to importing inner membrane carrier proteins, Tom70 is involved in targeting Mcl-1 to outer membrane via an interl EELD sequence.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TOMM70A antibody

Immunofluorescence of purified MaxPab antibody to TOMM70A on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

TOMM70A (N-term) antibody

  Rabbit Polyclonal TOM70 Antibody  
Western blot analysis of TOM70 in 293 cell lysate with TOM70 antibody at 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TOMM70A (Center) antibody

  Rabbit Polyclonal TOM70 Antibody  
Western blot analysis of TOM70 in rat brain tissue lysate with TOM70 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TOMM70A antibody

  Rabbit Polyclonal TOM70 Antibody  
Western Blot: TOM70 Antibody [TA336526] - Detection of TOM70 in MCF7 mitochondrial lysate Rabbit Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TOMM70A (C-term) antibody

Western blot analysis of TOMM70A antibody (C-term) (AP17798PU-N) in HL60 cell line lysates (35ug/lane). TOMM70A (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TOMM70A antibody

Western blot analysis of TOMM70A in MCF-7 mitochondrial lysate with TOMM70A polyclonal antibody ( Cat# PAB11995 ). Rabbit Hu, Ms, Rt WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

TOMM70A (N-term) antibody

Human HeLa; WB Suggested Anti-TOMM70A Antibody. . Titration: 1.0 ug/ml. . Positive Control: Hela Whole Cell. TOMM70A is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells.; TOMM70A antibody - N-terminal region (ARP62159_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Hu
50 µg / €350.00
  AVIVA Systems Biology

TOMM70A antibody

TOMM70A Rabbit IgG Aff - Purified Hu, Ms WB
50 µg / €680.00
  Funakoshi Co., Ltd.

CRISPR

Catalog No. Species Donor Vector  

TOMM70A - human gene knockout kit via CRISPR

TOMM70A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TOMM70A - human gene knockout kit via CRISPR

TOMM70A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TOMM70A - human gene knockout kit via CRISPR

TOMM70A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TOMM70A - human gene knockout kit via CRISPR

TOMM70A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TOMM70A

TOMM70A Human
2 µg / €300.00
  Abnova Taiwan Corp.

TOMM70A

TOMM70A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TOMM70A

TOMM70A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TOMM70A 293T Cell Transient Overexpression Lysate(Denatured)

TOMM70A 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TOMM70A (mGFP-tagged)-Human translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) (TOMM70A), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL

Lenti ORF particles, TOMM70A (mGFP-tagged)-Human translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) (TOMM70A), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, TOMM70A (Myc-DDK-tagged)-Human translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) (TOMM70A), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL

Lenti ORF particles, TOMM70A (Myc-DDK-tagged)-Human translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) (TOMM70A), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tomm70a (GFP-tagged ORF) - Rat translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) (Tomm70a), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL

Lenti ORF particles, Tomm70a (GFP-tagged ORF) - Rat translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) (Tomm70a), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL  
200 µl / €1,260.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tomm70a (Myc-DDK-tagged ORF) - Rat translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) (Tomm70a), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL

Lenti ORF particles, Tomm70a (Myc-DDK-tagged ORF) - Rat translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) (Tomm70a), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL  
200 µl / €1,133.00
  OriGene Technologies, Inc.

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