TOP2B antibody

Principal name

TOP2B antibody

Alternative names for TOP2B antibody

DNA topoisomerase 2-beta, DNA topoisomerase II beta isozyme

SwissProt ID

O42131 (Chick), Q02880 (Human), Q64511 (Mouse)

Gene ID

7155 (TOP2B), 4342925 (Os07g0280200)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Mky (Monkey), Por (Porcine), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TOP2B antibody

TOP2B is a D topoisomerase, an enzyme that controls and alters the topologic states of D during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsiol stress that occurs during D transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex D which allows the strands to pass through one another, thus altering the topology of D. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. This gene encodes a D topoisomerase, an enzyme that controls and alters the topologic states of D during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsiol stress that occurs during D transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex D which allows the strands to pass through one another, thus altering the topology of D. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, beta, is localized to chromosome 3 and the alpha form is localized to chromosome 17. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. Altertive splicing of this gene results in two transcript variants; however, the second variant has not yet been fully described. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

20 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TOP2B antibody

Western blot analysis of HeLa cell lysates with anti-TOP2B antibody (1:200). This antibody, under reducing conditions, identified a band of ~180kDa in HeLa cell lysates. Rabbit Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TOP2B antibody

Western blot analysis of extracts from Jurkat cells, using Topoisomerase II Ã?antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TOP2B antibody

WB Suggested Anti-TOP2B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Stomach Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

TOP2B antibody

WB Suggested Anti-TOP2B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Jurkat cell lysateTOP2B is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Can, Eq, GP, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

TOP2B antibody

Western blot analysis on Jurkat cell lysate using TOP2B Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TOP2B antibody

Western blot (WB) analysis of Topoisomerase II β antibody (Cat.-No.: AP06466PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

TOP2B antibody

TOP2B Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

TOP2B antibody

TOP2B Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

TOP2B antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TOP2B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
50 µg / €205.00
  Assay Biotech

TOP2B antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TOP2B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €310.00
  Assay Biotech

TOP2B antibody

Human Jurkat; WB Suggested Anti-TOP2B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Jurkat cell lysate. TOP2B is supported by BioGPS gene expression data to be expressed in Jurkat.; TOP2B antibody - middle region (ARP38011_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

TOP2B antibody

Immunohistochemical analysis of Topoisomerase 2 beta staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Can, Hu, Mky, Por ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

TOP2B antibody

Immunohistochemical analysis of Topoisomerase 2 beta staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Can, Hu, Mky, Por ICC/IF, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

TOP2B antibody

Immunohistochemical analysis of Topoisomerase 2 beta staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Can, Hu, Mky, Por ICC/IF, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

TOP2B antibody

Immunohistochemistry-Paraffin: Topo II beta Antibody [NB100-40842] - See Notes, IHC Caption B Rabbit Aff - Purified Hu IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

TOP2B antibody

Immunohistochemistry-Paraffin: Topo II beta Antibody [NB100-92111] - Paraffin-embedded human lung carcinoma tissue. Rabbit IgG Purified Hu, Ms P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

TOP2B antibody

TOP2B Rabbit IgG Aff - Purified Hu P
0.5 ml / €400.00
  Novus Biologicals Inc.

TOP2B antibody

Immunohistochemistry-Paraffin: TOP2B Antibody [NBP1-89527] - Immunohistochemical staining of human oral mucosa shows strong nuclear positivity in squamous epithelial cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TOP2B

TOP2B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TOP2B

TOP2B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

20 Item(s)

per page
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