TP53AIP1 antibody

Principal name

TP53AIP1 antibody

Alternative names for TP53AIP1 antibody

p53AIP1, p53-regulated apoptosis-inducing protein 1

SwissProt ID

Q9HCN2 (Human)

Gene ID

63970 (TP53AIP1)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TP53AIP1 antibody

The novel protein p53 AIP1, p53-regulated apoptosis inducing protein 1, has been identified from the direct cloning of p53 binding sequences from human genomic DNA. The expression of p53 AIP1 in mitochondria is induced by wild-type p53, which leads to apoptotic cell death through dissipation of mitochondrial Dym. Severe DNA damage causes the phosphorylation of p53 at Ser-46,p53 AIP1 expression, and apoptotic cell death. DNA damage-inducible apoptotic cell death was enhanced through transcriptional activation of p53 AIP1. P53R2 is directly regulated by p53 for supplying nucleotides to repair damaged DNA, thus plays a pivotal role in cell survival by repairing damaged DNA in the nucleus and that dysfunction of this pathway might result in activation of p53 dependent apoptosis to eliminate dangerous cells. In the opposite, p53 AIP1 is likely to play an important role in mediating p53-dependent apoptosis, and phosphorylation of Ser 46 regulates the transcriptional activation of this apoptosis inducing gene.

General readings

Oda K., et al. (2000). Cell 102:849-862

18 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TP53AIP1 antibody

Western blot analysis of p53AIP1 in HL60 cell lysate with p53AIP1 antibody at (A) 4 and (B) 8 ug/mL. Rabbit IgG Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TP53AIP1 antibody

Immunohistochemistry analysis of paraffin-embedded human thymus gland tissue using TPIP1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TP53AIP1 (N-term) antibody

AP07718PU-N P53AIP1 antibody staining of Formalin-Fixed Paraffin-Embedded Human Thymus at 5 µg/ml followed by biotinylated Goat anti-Rabbit IgG secondary antibody, Alkaline Phosphatase-Streptavidin and Chromogen. Rabbit Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TP53AIP1 Control Peptide

TP53AIP1
50 µg / €160.00
  Acris Antibodies GmbH

TP53AIP1 antibody

TP53AIP1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

TP53AIP1 antibody

Immunocytochemistry of P53AIP1 in HL-60 cells with P53AIP1 polyclonal antibody ( Cat # PAB12865 ) at 10 µg/ml. Rabbit Hu ICC/IF, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

TP53AIP1 antibody

Immunohistochemistry analysis of paraffin-embedded human thymus gland tissue, using TPIP1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P
50 µg / €205.00
  Assay Biotech

TP53AIP1 antibody

Immunohistochemistry analysis of paraffin-embedded human thymus gland tissue, using TPIP1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P
0.1 mg / €310.00
  Assay Biotech

TP53AIP1 antibody

Immunocytochemistry: p53 AIP1 Antibody [NBP1-47159] - Immunocytochemistry of p53AIP in HL60 cells with anti-p53AIP at 10 µg/ml. Rabbit Purified Hu E, ICC/IF, WB
50 µg / €360.00
  Novus Biologicals Inc.

TP53AIP1 antibody

TP53AIP1 Rabbit IgG Aff - Purified Hu E, ICC/IF, P
0.1 mg / €360.00
  Novus Biologicals Inc.

TP53AIP1 antibody

TP53AIP1 Rabbit IgG Aff - Purified Hu E, ICC/IF, P
50 µg / €290.00
  Novus Biologicals Inc.

TP53AIP1 antibody

Immunohistochemistry-Paraffin: p53 AIP1 Antibody [NBP1-76742] - HL60 cells with p53AIP1 antibody at 10 u/mL._x000d_ Rabbit Aff - Purified Hu E, ICC/IF, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TP53AIP1 (1-124, His-tag)

TP53AIP1 Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

TP53AIP1 (1-124, His-tag)

TP53AIP1 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

TP53AIP1

TP53AIP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TP53AIP1

TP53AIP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TP53AIP1 overexpression lysate

TP53AIP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

TP53AIP1 overexpression lysate

TP53AIP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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