TP53BP2 antibody

Principal name

TP53BP2 antibody

Alternative names for TP53BP2 antibody

p53-binding protein 2, p53BP2, 53BP2, Bcl2-binding protein, BBP, NY-REN-51, ASPP2, Apoptosis-stimulating of p53 protein 2, Tumor suppressor p53-binding protein 2

SwissProt ID

Q13625 (Human), Q8CG79 (Mouse)

Gene ID

7159 (TP53BP2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Macaque, Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of TP53BP2 antibody

This gene encodes a member of the ASPP(apoptosis-stimulating protein of p53 2) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates p53/TP53 by enhancing the DNA binding and transactivation function of p53/TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. [SUBCELLULAR LOCATION] Cytoplasm, perinuclear region. Nucleus.

General readings

Ju,H., et al., (2005) Int. J. Cancer 117 (6), 957-960

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TP53BP2 antibody

Western blot using Protein A purified anti-ASPP2 to detect over-expressed ASPP2 in MCF-7 cells (Lane 2, arrowhead). Lane 1 is a nontransfected control. Lane 3 is MCF-7 cells over-expressing ASPP1. Cell extracts were electrophoresed and transferred to nitrocellulose. The membrane was probed with the primary antibody at a 1:1,000 dilution. The identity of the lower MW band at approximately 40kDa is unknown. Personal Communication, H. Yang, Univ. Oklahoma, Oklahoma City, OK. Rabbit IgG Aff - Purified Can, Hu, Macaque E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TP53BP2 antibody

Predicted cell location: Cytoplasm. Positive control: Human gastric and colon cancer tissue. Recommended dilution: 1/10-50  The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TP53BP2 antibody at dilution 1/7, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TP53BP2 antibody

Predicted cell location: Cytoplasm. Positive control: Human gastric and colon cancer tissue. Recommended dilution: 1/5-20 The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA323358 (TP53BP2 Antibody) at dilution 1/5, on the right is treated with the synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA323358 (TP53BP2 Antibody) at dilution 1/5, on the right is treated with the synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TP53BP2 antibody

WB Suggested Anti-TP53BP2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Thymus Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

TP53BP2 (N-term) antibody

TP53BP2 Antibody (N-term) (AP54338PU-N) western blot analysis in T47D cell line lysates (35 µg/lane). This demonstrates the TP53BP2 antibody detected the TP53BP2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TP53BP2 antibody

TP53BP2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

TP53BP2 antibody

Immunoperoxidase of monoclonal antibody to TP53BP2 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml] Mouse IgG2a 3F8 Purified Hu E, P, WB
50 µg / €370.00
  Abnova Taiwan Corp.

TP53BP2 antibody

TP53BP2 Mouse IgG2a 1A10 Purified Hu E, WB
50 µg / €370.00
  Abnova Taiwan Corp.

TP53BP2 antibody

TP53BP2 Mouse IgG2a 1A10 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

TP53BP2 antibody

Western blot using TP53BP2 polyclonal antibody ( Cat # PAB9975 ) to detect over-expressed TP53BP2 in MCF-7 cells ( Lane 2, arrowhead ).
Lane 1 is a non-transfected control.
Lane 3 is MCF-7 cells over-expressing PPP1R13B.
Cell extracts were electrophoresed and transferred to nitrocellulose.
The membrane was probed with the primary antibody at a 1 : 1,000 dilution.
The identity of the lower MW band at approximately 40kDa is unknown.
Personal Communication, H. Yang, Univ. Oklahoma, Oklahoma City, OK. Hu, Macaque, Ms, Rt
0.1 mg / €560.00
  Abnova Taiwan Corp.

TP53BP2 antibody

Human Thymus; WB Suggested Anti-TP53BP2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Thymus; TP53BP2 antibody - N-terminal region (ARP38619_P050) in Human Thymus cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

TP53BP2 antibody

Western Blot and Immunoprecipitation: ASPP2 Antibody [NB100-2858] -Detection of Human ASPP2 on HeLa whole cell lysates using NB100-2858. ASPP2 was also immunoprecipitated by rabbit anti-ASPP2 antibody NB100-2859. Rabbit Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

TP53BP2 antibody

Immunohistochemistry-Paraffin: 53BP2 Antibody [NB100-2859] - FFPE section of human prostate adenocarcinoma.  Affinity purified rabbit anti-ASPP2 at a dilution of 1:500.  DAB staining using anti-Rabbit IHC antibody at a dilution of 1:100. Rabbit Aff - Purified Hu IP, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TP53BP2

TP53BP2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TP53BP2

TP53BP2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TP53BP2 overexpression lysate

TP53BP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

16 Item(s)

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