TPT1 / TCTP antibody

Principal name

TPT1 / TCTP antibody

Alternative names for TPT1 / TCTP antibody

Histamine-releasing factor, HRF, Fortilin, Translationally-controlled tumor protein

SwissProt ID

P13693 (Human), P28014 (Medsa), P43347 (Chick), P43348 (Rabit), P61288 (Pig), P63028 (Mouse), P63029 (Rat), Q5E984 (Bovin)

Gene ID

7178 (TPT1), 22070 (Tpt1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Flow Cytometry (F), Frozen Sections (C)

Background of TPT1 / TCTP antibody

Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. Histamine release is mediated by the stimulation of mast cells and basophils. Histamine-releasing factor (HRF) is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. HRF belongs to the translationally controlled tumor protein (TCTP) family and is detected as a protein of 21 kDa in mice and 23 kDa in human. It is expressed in several healthy and tumoral cells, including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas and lymphomas, and it is localized in the cytoplasm. HRF plays a pivotal role in allergic diseases, and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer’s disease and Down Syndrome.

General readings

Gross B., Nucleic Acids Res. 17:8367-8367(1989).
Dunham A., Nature 428:522-528(2004).
Hochstrasser D.F., Electrophoresis 13:992-1001(1992).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TPT1 / TCTP antibody

TPT1 monoclonal antibody (M03), clone 2C4. Western Blot analysis of TPT1 expression in NIH/3T3(Cat # L018V1 ). Mouse IgG2a 2C4 Purified Hu, Ms, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TPT1 / TCTP antibody

Western blot analysis of extracts from HepG2 cells, COLO205 cells and HeLa cells, using TCTP antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TPT1 / TCTP antibody

Western blot analysis of TPT1 in human brain tissue lysate with TPT1 antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TPT1 / TCTP antibody

Western blot analysis of TPT1 Antibody (N-term) (arrow) using rabbit polyclonal TPT1 Antibody (N-term) (Cat.  #TA324631).  293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TPT1 gene.  A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Rabbit IgG Purified Hu, Por WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

TPT1 / TCTP (Center) antibody

TPT1 Antibody (Center) (Cat. #TA325038) western blot analysis in LNCaP cell line lysates (35ug/lane).This demonstrates the TPT1 antibody detected the TPT1 protein (arrow). Rabbit Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

TPT1 / TCTP antibody

HeLa (Lane 1) and A20 (Lane2) cell extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with polyclonal anti-HRF/N19 antibody. Proteins were visualized using a donkey anti-rabbit secondary conjugated to HRP and chemiluminescence detection. Rabbit IgG Poly6165 Purified Hu, Ms WB
0.2 ml / €325.00
  OriGene Technologies, Inc.

TPT1 / TCTP antibody

Western blot analysis of extracts of various cell lines, using TPT1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

TPT1 / TCTP antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-TPT1 Rabbit Polyclonal antibody. (TA590155) Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

TPT1 / TCTP (1-172) antibody

Immunohistochemical detection of HRF/TCTP on paraffin embedded section of Human pancreas AM26634AF-N. Mouse IgG1 6E9 Azide Free Hu, Ms, Rt IP, P, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

TPT1 / TCTP antibody

Immunohistochemistry (IHC) analyzes of HRF antibody (Cat.-No.: AP06666PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

TPT1 / TCTP antibody

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TPT1 / TCTP antibody

TPT1 / TCTP Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

TPT1 / TCTP antibody

TPT1 / TCTP Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

TPT1 / TCTP antibody

Immunofluorescence of monoclonal antibody to TPT1 on HeLa cell. [antibody concentration 30 ug/ml] Mouse IgG1 3C7 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TPT1 / TCTP antibody

TPT1 / TCTP Mouse IgG2b 2A3 Purified Hu, Ms, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TPT1 / TCTP antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TCTP Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

TPT1 / TCTP antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TCTP Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €310.00
  Assay Biotech

TPT1 / TCTP antibody

Immunohistochemical analysis of TCTP staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Por, Rb ICC/IF, IP, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

TPT1 / TCTP antibody

Immunohistochemical analysis of TCTP staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Por, Rb ICC/IF, IP, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

TPT1 / TCTP antibody

Immunohistochemical analysis of TCTP staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Por, Rb ICC/IF, IP, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

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