TPX2 / DIL2 antibody

Principal name

TPX2 / DIL2 antibody

Alternative names for TPX2 / DIL2 antibody

DIL-2, C20orf1, C20orf2, HCA519, Targeting protein for Xklp2, Restricted expression proliferation-associated protein 100, Differentially expressed in cancerous and non-cancerous lung cells 2, Hepatocellular carcinoma-associated antigen 519

SwissProt ID

Q9ULW0 (Human)

Gene ID

22974 (TPX2)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Gt (Goat), Hst (Hamster), Sh (Sheep), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of TPX2 / DIL2 antibody

The TPX2 protein, also known as targeting protein for Xklp1, restricted expression proliferation associated protein p100, and differentially expressed in cancer and non-cancerous lung cells protein 2 (DIL2), is a 100 kD nuclear protein that contains two coiled-coil domains. The TPX2 protein is strictly associated with spindle pole and mitotic spindle during mitosis. In the G2/S position of the cell cycle, TPX2 is diffusely distributed throughout nucleus. TPX2 has been shown to be highly expressed in lung carcinomas cell lines, but not in normal lung tissues. TPX2 is thought to be required for the Ran-GTP dependent assembly of microtubules around chromosomes required to generate stable bipolar spindle with overlapping anti-parallel microtubule arrays and may also be involved in targeting Aurora-A kinase to the mitotic spindle. TPX2 has been shown to interact with a large number of proteins including serine/threonine protein kinase 6, ribosomal protein 6, Bop-1, α-tubulin, and nucleolin among others. TPX2 can be modified by phosphorylation on serine 738.

General readings

Szczepanowski,M., (2007) Biochem. Biophys. Res. Commun. 362 (2), 485-490

19 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TPX2 / DIL2 antibody

  Rabbit Polyclonal Antibody against TPX2  
Western Blot: TPX2 Antibody TA301667 - Analysis of TPX2 expression in 1) HeLa, 2) Ntera2, 3) K-562 and 4) Raji whole cell lysates using NB500-179. Rabbit IgG Purified Bov, Gt, Hst, Hu, Ms, Sh WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TPX2 / DIL2 antibody

  Rabbit polyclonal anti-DIL-2 (TPX2) antibody  
Western blot analysis of extracts from Jurkat cells, using DIL-2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TPX2 / DIL2 (1-220) antibody

  Mouse Monoclonal anti-TPX2 Antibody  
MOLT-4 nuclear extracts were resolved by electrophoresis, transferred to nitrocellulose and probed with monoclonal anti-TPX2 (clone 18D5) antibody. Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system. Mouse IgG1 18D5 Aff - Purified Hu ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TPX2 / DIL2 antibody

  Rabbit Polyclonal Anti-TPX2 Antibody  
WB Suggested Anti-TPX2 Antibody Titration: 0.2-1 ug/ml; Positive Control: 721_B cell lysate.TPX2 is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

TPX2 / DIL2 antibody

  Rabbit Polyclonal Anti-TPX2 Antibody  
Gel: 6%SDS-PAGE,Lysate: 40 ug,Lane 1-4: A431 cells, 293T cells, Hela cells, K562 cells,Primary antibody: (TPX2 Antibody) at dilution 1/800 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 10 seconds Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TPX2 / DIL2 antibody

Figure 1. Western analysis of extracts from Jurkat cells using P100 antibody (Cat. #AM11020PU-N). Mouse IgG1 19AT738.292 Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TPX2 / DIL2 antibody

Figure 1. Western analysis of extracts from Jurkat cells using P100 antibody (Cat. #AM11022PU-N). Mouse IgG1 19AT953.286.93 Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TPX2 / DIL2 antibody

Immunohistochemistry (IHC) analyzes of TPX2 antibody (Cat.-No.: AP01372PU-N) in paraffin-embedded human brain tissue Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

TPX2 / DIL2 antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TPX2 / DIL2 antibody

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Ms E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TPX2 / DIL2 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DIL-2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
50 µg / €230.00
  Assay Biotech

TPX2 / DIL2 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DIL-2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

TPX2 - human gene knockout kit via CRISPR

TPX2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TPX2 - human gene knockout kit via CRISPR

TPX2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TPX2 - human gene knockout kit via CRISPR

TPX2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TPX2 - human gene knockout kit via CRISPR

TPX2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TPX2 / DIL2

  Recombinant protein of human TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2)  
TPX2 / DIL2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TPX2 (mGFP-tagged) - Human TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2), 200 uL, >10^7 TU/mL

Lenti ORF particles, TPX2 (mGFP-tagged) - Human TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, TPX2 (Myc-DDK tagged) - Human TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, TPX2 (Myc-DDK tagged) - Human TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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