Transferrin antibody

Principal name

Transferrin antibody

Alternative names for Transferrin antibody

Serotransferrin, Siderophilin, Beta-1 metal-binding globulin

SwissProt ID

P02787 (Human), P09571 (Pig), P12346 (Rat), P19134 (Rabit), P27425 (Horse), Q29443 (Bovin), Q921I1 (Mouse)

Gene ID

7018 (TF), 22041 (Trf), 100009267 (TRF), 24825 (Tf), 280705, 100034176

Available reactivities

Hu (Human), Por (Porcine), Rb (Rabbit), Rt (Rat), Fe (Feline), GP (Guinea Pig), Ms (Mouse), Bov (Bovine), Eq (Equine)

Available hosts

Rabbit, Mouse, Sheep, Goat, Chicken, Rat

Available applications

Frozen Sections (C), Paraffin Sections (P), Enzyme Immunoassay (E), Functional assay (FN), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Radioimmunoassay (R), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), ELISA (capture) (E(capture)), Immunodiffusion (ID), Immunoelectron Microscopy (EM), Neutralisation (NEUT), Dot blot (Dot), Flow Cytometry (F)

Background of Transferrin antibody

Transferrin is a monomeric glycoprotein of approximately 77 kDa, which serves as an iron-transporter. In normal plasma, transferrin has a concentration of 25-50 µmol / liter, and is usually about one-third saturated with iron, thus providing a large buffering capacity in case of an acute increase in plasma iron levels. Cells take up transferrin-iron complexes (holotransferrin) using transferrin receptor dimers. Upon binding of holotransferrin, the receptor is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with its receptor (CD71) and recycles to the cell surface, where apotransferrin is released upon exposure to normal pH. Internalization of labeled transferrin thus represents an usefull approach to study endocytosis. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. Iron/transferrin complex is essential in haemoglobin synthesis and for certain types of cell division.

General readings

This product has been used in:Bartek J et al. Phylogenetically more conservative epitopes among monoclonal antibody-defined antigenic sites of human transferrin are involved in receptor binding. Br J Haematol 59:435-41 (1985). PubMed PMID: 2578807
Bartek J et al. Monoclonal antibodies against transferrin. Precipitating mixtures and lack of inter-species cross-reactivity. Immunol Lett 4:231-5 (1982). PubMed PMID: 7095835

  1. Quick-Filters:
  2. Cited (1)
  3. Highly Validated (1)

Items 1 to 20 of 88 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Transferrin (N-term) antibody

Immunohistochemistry:  AM08317PU-N Transferrin antibody staining of Formalin-Fixed Paraffin-Embedded Human Placenta tissue at 10 µg/ml. Mouse IgG1 HTF-14 Purified Hu, Por, Rb E, FN, ICC/IF, IP, R, WB
0.1 mg / €210.00
  Acris Antibodies GmbH

Transferrin antibody

Anti-TF mouse monoclonal antibody (TA500848) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TF(RC209184). Mouse IgG1 OTI5G2 Purified Hu F, ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Transferrin antibody

Gel: 6%SDS-PAGE, Lysate: 40 µg, Lane 1-2: Human kidney tissue, Human prostate tissue, Primary antibody:TF Antibody at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Transferrin antibody

Gel: 6%SDS-PAGE,Lysate: 40 µg,,Primary antibody:TF Antibody at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 40 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Transferrin antibody

Transferrin Goat IgG Purified Hu E
1 mg / €380.00
  Acris Antibodies GmbH

Transferrin antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Brain, cortex. Rabbit Aff - Purified Hu E, ICC/IF, P
50 µg / €470.00
  Acris Antibodies GmbH

Transferrin antibody

Transferrin Rabbit IgG Purified Hu E, IP
1 ml / €320.00
  Acris Antibodies GmbH

Transferrin antibody

Transferrin Rabbit IgG Purified Hu E, IP
0.5 ml / €250.00
  Acris Antibodies GmbH

Transferrin antibody

AP08815PU-N at 5 µg/ml, staining Serotransferrin  in Formalin-Fixed, Paraffin-Embedded Human Liver tissue by Immunohistochemistry. Rabbit IgG Purified Hu E, IP, P, WB
500 µg / €470.00
  Acris Antibodies GmbH

Transferrin antibody

Transferrin Rabbit IgG HRP Hu C, Dot, E, WB
0.5 mg / €440.00
  Acris Antibodies GmbH

Transferrin antibody

Transferrin Rabbit IgG Aff - Purified Hu C, E, WB
1 mg / €1,150.00
  Acris Antibodies GmbH

Transferrin antibody

Transferrin Rabbit IgG Aff - Purified Ms C, E, WB
1 mg / €1,150.00
  Acris Antibodies GmbH

Transferrin antibody

Transferrin Goat Serum Hu ID, IP
1 ml / €250.00
  Acris Antibodies GmbH

Transferrin antibody

Western blot analysis of human serum transferrin (1.5 μg) using anti-human transferrin polyclonal antibody. Rabbit Azide Free Hu E, WB
0.5 mg / €360.00
  Acris Antibodies GmbH

Transferrin antibody

Transferrin Goat Serum Por ID, IP
1 ml / €250.00
  Acris Antibodies GmbH

Transferrin antibody

Transferrin Rabbit Serum Rt ID, IP
1 ml / €250.00
  Acris Antibodies GmbH

Transferrin antibody

Transferrin Rabbit Azide Free Por C, Dot, E, ICC/IF, ID, IP, WB
10 mg / €380.00
  Acris Antibodies GmbH

Transferrin antibody

Transferrin Rabbit Biotin Por C, Dot, E, ICC/IF, ID, IP, WB
1 ml / €430.00
  Acris Antibodies GmbH

Transferrin antibody

Transferrin Rabbit FITC Por C, E, ICC/IF, ID, WB
1 ml / €340.00
  Acris Antibodies GmbH

Transferrin antibody

Transferrin Rabbit HRP Por C, Dot, E, ICC/IF, ID, IP, WB
1 ml / €430.00
  Acris Antibodies GmbH

Items 1 to 20 of 88 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  • LinkedIn