Transglutaminase-2 (TGM2) antibody

Principal name

Transglutaminase-2 (TGM2) antibody

Alternative names for Transglutaminase-2 (TGM2) antibody

TGase C, TGase-H, Tissue transglutaminase, Protein-glutamine gamma-glutamyltransferase 2

SwissProt ID

P21980 (Human), P21980-2, P21981 (Mouse), P51176 (Bovin), Q01841 (Chick)

Gene ID

7052 (TGM2), 9333 (TGM5), 116179 (TGM7), 21817 (Tgm2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), GP (Guinea Pig), Rb (Rabbit), Bov (Bovine), Por (Porcine), Chk (Chicken), Ze (Zebrafish), Mky (Monkey)

Available hosts

Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Frozen Sections (C), Functional assay (FN), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of Transglutaminase-2 (TGM2) antibody

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, TGM2 is the autoantigen implicated in celiac disease.Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

General readings

Verma A, Wang H, Manavathi B, Fok JY, Mann AP, Kumar R, Mehta K. Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis. Cancer Res. 2006 Nov 1;66(21):10525-33. PMID: 17079475

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Transglutaminase-2 (TGM2) antibody

TA303243 (0.03µg/ml) staining of Human Lung lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
20 µg / €200.00
  Acris Antibodies GmbH

Transglutaminase-2 (TGM2) antibody

TA303243 (0.03µg/ml) staining of Human Lung lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Transglutaminase-2 (TGM2) (578-591) antibody

TA309513 (1µg/ml) staining of Mouse Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Transglutaminase-2 (TGM2) antibody

Western blot analysis of extracts from HuvEc cells, using Transglutaminase 2 antibody (#TA312164).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Transglutaminase-2 (TGM2) antibody

Predicted band size: 77 kDa . Positive control: Lovo and hela cell, human liver cancer and fetal liver tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: Lovo cell lysate Lane2: Hela cell lysate Lane3: Human liver cancer tissue lysate Lane4:Human fetal liver tissue lysate Lysate: 50 ug per lane Primary antibody: 1/150 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Transglutaminase-2 (TGM2) antibody

Predicted band size: 77 kDa . Positive control: Lovo and hela cell, human liver cancer tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: Lovo lysate Lane2: Hela cell lysate Lane3: Human liver cancer tissue lysate Lysates: 50 ug per lane Primary antibody: 1/150 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Transglutaminase-2 (TGM2) (Center) antibody

TGM2 Antibody (Center K444) (Cat. #TA324993) western blot analysis in HUVEC,K562 cell line lysates (35ug/lane).This demonstrates the TGM2 antibody detected the TGM2 protein (arrow). Rabbit Ig Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Transglutaminase-2 (TGM2) (C-term) antibody

TA326310 (0.05µg/ml) staining of Human Pancreas cancer lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Transglutaminase-2 (TGM2) antibody

Western blot analysis of extracts of Hela cell and HepG2 cell lysate using TGM2 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Transglutaminase-2 (TGM2) antibody

Western blot analysis on HuvEc cell lysate using TGM2 Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Transglutaminase-2 (TGM2) antibody

Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) using TGM2 antibody Mouse IgG 2A1 Purified Hu E, IP, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Transglutaminase-2 (TGM2) antibody

Transglutaminase-2 (TGM2) Rabbit Serum Hu E
0.1 ml / €620.00
  Acris Antibodies GmbH

Transglutaminase-2 (TGM2) antibody

Transglutaminase-2 (TGM2) Rabbit Serum Hu E
20 µl / €200.00
  Acris Antibodies GmbH

Transglutaminase-2 (TGM2) antibody

Immunohistochemistry (IHC) analyzes of Transglutaminase 2  antibody (Cat.-No.: AP06356PU-N)  in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Transglutaminase-2 (TGM2) antibody

Placenta: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt IP, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Transglutaminase-2 (TGM2) antibody

Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) using Transglutaminase-2 antibody. Rabbit IgG Purified Hu, Ms, Rt E, IP, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Transglutaminase-2 (TGM2) antibody

Transglutaminase-2 (TGM2) Rabbit Biotin Hu E, WB
0.2 ml / €420.00
  Acris Antibodies GmbH

Transglutaminase-2 (TGM2) antibody

Western Blot (10% gel) with TGM2 antibody Cat.-No AP10441PU-N Rabbit Purified Hu C, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Transglutaminase-2 (TGM2) (Center) antibody

Western blot analysis of TGM2 (arrow) using rabbit polyclonal TGM2 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (c) or transiently transfected with the TGM2 gene (Lane 2) Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Transglutaminase-2 (TGM2) (full length) antibody

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Ms, Rt IP, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

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